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公开(公告)号:WO2013007967A1
公开(公告)日:2013-01-17
申请号:PCT/GB2012/000567
申请日:2012-07-03
Applicant: UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS , GIARDINI, Mario Ettore , KRSTAJIC, Nikola
Inventor: GIARDINI, Mario Ettore , KRSTAJIC, Nikola
CPC classification number: G01B9/02019 , A61B5/0066 , A61B5/441 , A61B5/7257 , G01B9/02044 , G01B9/02057 , G01B9/02091 , G01N21/4795
Abstract: A Fourier-domain OCT system for capturing images of a sample, the system comprising an interferometer that has a reference arm and a sample arm, wherein the reflective part of the reference arm comprises the sample surface or an optically diffusive material applied to the sample surface.
Abstract translation: 一种用于捕获样本图像的傅立叶域OCT系统,该系统包括具有参考臂和样本臂的干涉仪,其中参考臂的反射部分包括样品表面或施加到样品表面的光学漫射材料 。
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公开(公告)号:WO2012175918A1
公开(公告)日:2012-12-27
申请号:PCT/GB2012/000537
申请日:2012-06-20
Applicant: UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS , DHOLAKIA, Kishan , MARCHINGTON, Robert , ARITA, Yoshihiko , GUNN-MOORE, Frank
Inventor: DHOLAKIA, Kishan , MARCHINGTON, Robert , ARITA, Yoshihiko , GUNN-MOORE, Frank
CPC classification number: C12M35/02 , B01L3/502715 , B01L3/502761 , C12N13/00 , G01N21/05 , G01N2021/0346
Abstract: A cell permeablising microfluidic system for permeablising one or more cells in a fluid flow. The system has a microfluidic channel for channelling at least one cell in a fluid flow and an optical source for generating a beam of light for permeablising the at least one cell, wherein the channel and the source are arranged so that the light beam and fluid flow are collinear in a permeablisation part of the channel and cells are permeablised within the permeablisation part.
Abstract translation: 用于渗透流体流中的一个或多个细胞的细胞渗透微流体系统。 该系统具有用于引导流体流中的至少一个细胞的微流体通道和用于产生用于使至少一个细胞渗透的光束的光源,其中通道和源被布置成使得光束和流体流动 在通道的渗透部分中共线,并且细胞在渗透部分内渗透。
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公开(公告)号:WO2012028936A1
公开(公告)日:2012-03-08
申请号:PCT/IB2011/002003
申请日:2011-08-30
Applicant: UNIVERSITEIT LEIDEN , ORRIT, Michel , GAIDUK, Alexander
Inventor: ORRIT, Michel , GAIDUK, Alexander
IPC: B82Y30/00
CPC classification number: B82Y30/00
Abstract: The present invention provides a method of increasing fluorescence of metal nanoparticles (NPs), as well as the metal nanoparticles with increased fluorescence themselves. The present invention relates to a system and method for simultaneously performing photothermal microscopy and fluorescence detection of metal, such as gold, nanoparticles (NPs).
Abstract translation: 本发明提供了增加金属纳米颗粒(NP)的荧光的方法以及本身具有增加的荧光的金属纳米颗粒。 本发明涉及同时对金,纳米粒子(NP)等金属进行光热显微镜和荧光检测的系统和方法。
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公开(公告)号:WO2012013925A2
公开(公告)日:2012-02-02
申请号:PCT/GB2011/001118
申请日:2011-07-26
Applicant: UNIVERSITY OF STRATHCLYDE , GOURLAY, Terrence
Inventor: GOURLAY, Terrence
IPC: A61M1/16
CPC classification number: A61M1/32 , A61M1/1006 , A61M1/101 , A61M1/1015 , A61M1/1029 , A61M1/1036 , A61M1/1698 , A61M1/262 , A61M1/267 , A61M1/369 , A61M2205/3673
Abstract: An integrated perfusion apparatus or device for use in e.g. extracorporeal membrane oxygenation, cardiopulmonary bypass, or isolated organ or limb perfusion, comprises a blood pump for circulating blood through the device; a blood oxygenator for oxygenating blood, and at least one heat control unit capable of controlling and/or regulating blood temperature within the device, wherein the at least one heat control unit comprises at least one solid state heating and/or cooling source, such as at least one Peltier device. The invention also relates to a method of performing perfusion on a patient, limb or organ, comprising using the perfusion device.
Abstract translation: u> u> u> 使用于例如 体外膜式氧合,体外循环或分离的器官或肢体灌注,包括用于使血液循环通过装置的血泵; 用于使血液充氧的血液充氧器以及能够控制和/或调节装置内的血液温度的至少一个热量控制单元,其中所述至少一个热量控制单元包括至少一个固态加热和/或冷却源,例如 至少一个珀尔帖装置。 本发明还涉及对患者,肢体或器官进行灌注的方法,包括使用灌注装置。 p>
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公开(公告)号:WO2012007727A1
公开(公告)日:2012-01-19
申请号:PCT/GB2011/001073
申请日:2011-07-18
Applicant: UNIVERSITY OF STRATHCLYDE , TAO, Shanwen , LAN, Rong
Inventor: TAO, Shanwen , LAN, Rong
CPC classification number: H01M8/222 , C08J5/225 , C08J5/2281 , C08J2327/00 , H01M4/9016 , H01M4/96 , H01M8/1018
Abstract: The invention provides a method of operating a fuel cell that comprises a solid cation exchange membrane, the method comprising contacting an anode in the fuel cell with urine, an ammonium salt or a urea salt and contacting the cathode with an oxidant whereby to generate electricity.
Abstract translation: 本发明提供一种操作包括固体阳离子交换膜的燃料电池的方法,该方法包括使燃料电池中的阳极与尿液,铵盐或脲盐接触,并使阴极与氧化剂接触,从而产生电力。
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公开(公告)号:WO2011157990A1
公开(公告)日:2011-12-22
申请号:PCT/GB2011/000899
申请日:2011-06-16
Applicant: UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS , DUNN, Malcolm Harry , RAE, Cameron Francis , STOTHARD, David James Mark , WALSH, David Alan
Inventor: DUNN, Malcolm Harry , RAE, Cameron Francis , STOTHARD, David James Mark , WALSH, David Alan
IPC: G02F1/39
CPC classification number: G02F1/39 , G02F2203/13
Abstract: A method of optimising parametric gain in a nonlinear optical crystal that in response to application of a pump beam generates through a parametric generation process signal and idler beams, wherein the signal beam is non-collinear with the pump beam and the signal beam is subject to absorption due to the nonlinear material, the method involving shaping the pump beam to have an elliptical cross section, wherein the method further involves determining the width w of the pump beam depending on the absorption co- efficient of the optical crystal.
Abstract translation: 一种在非线性光学晶体中优化参数增益的方法,其响应于泵浦光束的应用产生通过参数生成过程信号和空载光束,其中信号光束与泵浦光束非共线并且信号光束经受 由于非线性材料的吸收,涉及将泵浦光束成形为具有椭圆形截面的方法,其中该方法还包括根据光学晶体的吸收系数确定泵浦光束的宽度w。
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公开(公告)号:WO2011121290A2
公开(公告)日:2011-10-06
申请号:PCT/GB2011/000481
申请日:2011-03-30
Applicant: UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS , DUNN, Malcolm, Harry , MILLER, Graham, M. , WALKER, Donald
Inventor: DUNN, Malcolm, Harry , MILLER, Graham, M. , WALKER, Donald
CPC classification number: G02B6/3816 , G02B6/0006 , G02B6/0008 , G02B6/3891 , G02B6/3897 , G02B6/403 , G02B6/4248
Abstract: An optical device comprising a sealed / closed housing; a light source and/or a detector within the housing; a window through the housing that is transparent to light transmitted from the light source or to the detector and a fixing for fixing an optical fibre or bundle of such fibres into a coupling position adjacent to the window to allow light to pass between the housing and the fibre or fibre bundle, wherein the fixing is adapted to allow connection and/or disconnection of the fibre or fibre bundle without opening or breaking a seal of the sealed housing.
Abstract translation: 一种光学装置,包括密封/封闭的壳体; 壳体内的光源和/或探测器; 通过壳体的透光的窗口,其对于从光源或检测器传输的光是透明的,以及用于将这种光纤或光纤束固定到与窗口相邻的耦合位置的定影,以允许光在壳体和 纤维或纤维束,其中所述固定适于允许所述纤维或纤维束的连接和/或断开,而不打开或破坏所述密封壳体的密封。
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公开(公告)号:WO2011107755A2
公开(公告)日:2011-09-09
申请号:PCT/GB2011/000314
申请日:2011-03-04
Applicant: UNIVERSITY OF STRATHCLYDE , MULLEN, Alexander , STEVENS, Howard , ECCLESTON, Sarah
Inventor: MULLEN, Alexander , STEVENS, Howard , ECCLESTON, Sarah
IPC: A61K9/24
CPC classification number: A61K9/2054 , A61K9/2018 , A61K9/2068 , A61K9/209 , A61K31/00 , A61K31/196 , A61K38/00
Abstract: In one aspect, the present invention is concerned with a treatment where it is desired that an active agent is designed to be released immediately following administration and again at a time point some time after administration of the active agent. The present invention is particularly suited to administering an agent which may be released before sleep and whilst a subject is sleeping. As well as treating certain conditions by a particular regime, the invention also provides novel formulations for an immediate, followed by a delayed release of drug.
Abstract translation: 在一个方面,本发明涉及治疗,其中期望活性剂被设计为在施用后立即释放,并且再次在施用活性剂后一段时间释放。 本发明特别适用于在睡眠之前和受试者正在睡觉时可以释放的药剂。 除了通过特定方案治疗某些病症之外,本发明还提供用于立即,随后延迟释放药物的新型制剂。
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公开(公告)号:WO2011030110A4
公开(公告)日:2011-03-17
申请号:PCT/GB2010/001715
申请日:2010-09-10
Applicant: UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS , CLARKE, Matthew Lee , KONRAD, Tina Maria
Inventor: CLARKE, Matthew Lee , KONRAD, Tina Maria
Abstract: The invention provides a method for the hydroxycarbonylation, alkoxycarbonylation, aryloxycarbonylation or thiocarbonylation of an unsaturated molecule comprising effecting a hydroxycarbonylation, alkoxycarbonylation, aryloxycarbonylation or thiocarbonylation reaction on the unsaturated molecule in which a complex comprising a ligand comprising a [n,n']cyclophane comprising two non-fused monocyclic aromatic rings bridged by two linear and aliphatic linkages, in which each of the non-fused monocyclic aromatic rings is substituted with a phosphorus atom-containing substituent, is used to catalyse the hydroxycarbonylation, alkoxycarbonylation, aryloxycarbonylation or thiocarbonylation reaction.
Abstract translation: 本发明提供了一种不饱和分子的羟基羰基化,烷氧基羰基化,芳氧基羰基化或硫代羰基化的方法,该方法包括对不饱和分子进行羟基羰基化,烷氧基羰基化,芳氧基羰基化或硫代羰基化反应,其中包含配体 包含两个通过两个线性和脂肪族键桥接的非稠合单环芳环的环[n,n']环烷烃,其中每个非稠合单环芳环被含磷原子取代基取代,用于催化羟基羰基化 ,烷氧基羰基化,芳氧基羰基化或硫代羰基化反应。 p>
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公开(公告)号:WO2010139969A1
公开(公告)日:2010-12-09
申请号:PCT/GB2010/001126
申请日:2010-06-04
Applicant: POLYFORMERS LIMITED , HUTCHON, Bruce
Inventor: HUTCHON, Bruce
Abstract: A cistern (5) comprising a tank (10) connected to an outlet (40, 45) via an outlet valve (50, 55), the outlet valve comprising at least one elongate flap (140, 145). The tank may comprise at least two chambers (15, 20). The at least two chambers may be formed by at least one divider in the tank. Alternatively, the tank may be modular and the chamber may be separate, individually removable parts (250, 255).
Abstract translation: 包括通过出口阀(50,55)连接到出口(40,45)的罐(10)的水箱(5),所述出口阀包括至少一个细长翼片(140,145)。 罐可以包括至少两个室(15,20)。 该至少两个室可以由罐中的至少一个分隔器形成。 或者,罐可以是模块化的,并且室可以是单独的,可单独拆卸的部件(250,255)。
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