公开(公告)号：WO2022063650A1

公开(公告)日：2022-03-31

申请号：PCT/EP2021/075328

申请日：2021-09-15

Applicant: ABIOMED EUROPE GMBH

Inventor： GRAUWINKEL, Marius ,  KERKHOFFS, Wolfgang

IPC: A61M60/126 ,  A61M60/216 ,  A61M60/422 ,  A61M60/82 ,  A61M60/824 ,  A61M60/825 ,  A61M60/13 ,  A61M60/139 ,  A61M60/221 ,  A61M60/242

Abstract: This invention concerns an intravascular blood pump (1) for percutaneous insertion into a patient's blood vessel. The blood pump (1) comprises a pump casing (2) having a blood flow inlet (21) and a blood flow outlet (22), an impeller (3) arranged in said pump casing (2) so as to be rotatable about an axis of rotation (10). The impeller (3) has blades (31) sized and shaped for conveying blood from the blood flow inlet (21) to the blood flow outlet (22). The blood pump (1) comprises a drive unit (4) for rotating the impeller (3), the drive unit (4) comprising a magnetic core (400) including a plurality of posts (40) arranged about the axis of rotation (10) and a back plate (50) connecting the posts (40) and extending between the posts (40) in an intermediate area (59). A coil winding (44) is disposed around each of the posts (40). The coil windings (44) are controllable so as to create a rotating magnetic field, wherein the impeller (3) comprises a magnetic structure (32) arranged to interact with the rotating magnetic field so as to cause rotation of the impeller (3). A material of at least a portion of at least one of the posts (40) is integral with a material of the intermediate area (59) of the back plate (50). Further, the invention concerns a method of manufacturing a magnetic core (400) and a method of manufacturing an intravascular blood pump (1).

公开(公告)号：WO2021152019A1

公开(公告)日：2021-08-05

申请号：PCT/EP2021/052002

申请日：2021-01-28

Applicant: ABIOMED EUROPE GMBH

Inventor： SPANIER, Gerd ,  SIESS, Thorsten

IPC: A61M60/13 ,  A61M60/414 ,  A61M60/205 ,  A61M60/808 ,  A61M60/825

Abstract: An intravascular blood pump (1) comprises a pumping device and a catheter (5). The pumping device comprises a drive shaft (12), a rotor (10) located at a distal end of the drive shaft (5), a housing (11), in which the rotor (10) is housed, and a distal bearing (14) for rotatably supporting a distal end of the rotor (10). The distal bearing (14) comprises a static support member (18), which protrudes into or up against the distal end of the rotor (10). The rotor (10) and housing (11) may be expandable, and the pin (19) may have a sufficient length to prevent disengagement of the pin (19) from the distal end of the rotor (10) when the rotor (10) and the housing (11) are in a collapsed state.

公开(公告)号：WO2021043776A1

公开(公告)日：2021-03-11

申请号：PCT/EP2020/074371

申请日：2020-09-01

Applicant: ABIOMED EUROPE GMBH

Inventor： KERKHOFFS, Wolfgang ,  GRAUWINKEL, Marius

IPC: A61M1/12 ,  A61M1/10

Abstract: This invention concerns an intravascular blood pump for percutaneous insertion into a patient's blood vessel. The blood pump comprises a pump casing (2) having a blood flow inlet (21) and a blood flow outlet (22), and an impeller (3) arranged in said pump casing (2) so as to be rotatable about an axis of rotation (10). The impeller (3) has blades (31) sized and shaped for conveying blood from the blood flow inlet (21) to the blood flow outlet (22). The blood pump comprises a drive unit (4) for rotating the impeller (3), the drive unit (4) comprising a plurality of posts (40) arranged about the axis of rotation (10). Each of the posts (40) has an impeller-side end (420) pointing towards the impeller (3) with a front surface (42) facing the impeller (3). A coil winding (44) is disposed around each of the posts (40) so as to create magnetic field lines (500) running through the front surface (42) of each of the posts (40) and controllable so as to create a rotating magnetic field, wherein the impeller (3) comprises a magnetic structure (32) arranged to interact with the rotating magnetic field so as to cause rotation of the impeller (3). The front surface (42) of at least one of the posts (40) comprises a concavity in which the front surface (42) is inclined downwards towards a central area of the front surface (42) so as to concentrate at least a part of the magnetic field lines (500) running through the front surface (42).

公开(公告)号：WO2018234454A1

公开(公告)日：2018-12-27

申请号：PCT/EP2018/066590

申请日：2018-06-21

Applicant: ABIOMED EUROPE GMBH

Inventor： ABOULHOSN, Walid ,  SIESS, Thorsten ,  KIRCHHOFF, Frank

IPC: A61M1/10 ,  A61M1/12

Abstract: A method of manufacturing a cannula (4) for an intravascular blood pump comprises the steps of forming a first axial section (13) and a second axial section (15) of an elongate tubular body of the cannula (4) by dispensing a first liquid material and a second liquid material, respectively, onto a mandrel (7) by means of at least one dispenser (8). The mandrel (7) is rotated and the dispenser (8) moves relative to the mandrel (7) in an axial direction during dispensing of the liquid materials. The first and second axial sections (13,15) are formed so as to have different bending stiffnesses. The first and second liquid materials are dispensed onto the mandrel (7) such that the first and second liquid materials blend into each other to form a smooth transition area (14).

公开(公告)号：WO2017137604A1

公开(公告)日：2017-08-17

申请号：PCT/EP2017/053074

申请日：2017-02-10

Applicant: ABIOMED EUROPE GMBH

Inventor： SIESS, Thorsten ,  ABOULHOSN, Walid ,  KIRCHHOFF, Frank ,  NIX, Christoph ,  SPANIER, Gerd

IPC: A61M1/10 ,  A61M1/12

CPC classification number: A61M1/125 ,  A61M1/1008 ,  A61M1/122

Abstract: A blood pump (1) comprises a pump section (2) and a flow cannula (3). A proximal end portion (14) of the flow cannula (3) is connected to the pump section (2) such that blood can enter the blood flow inlet (11), and a distal end portion (13) of the flow cannula (3) includes at least one blood flow-through opening (16) for blood to enter the flow cannula (3). The distal end portion (13) comprises an enlarged diameter portion (15), with at least a major portion of the blood flow-through opening (16) being disposed in the enlarged diameter portion (15). The blood pump (1) further comprises a sleeve (4) overlapping the enlarged diameter portion (15). The sleeve (4) has a structure that prevents its distal end (42) from bending radially inwards into the blood flow- through openings (16).

Abstract translation: 血泵（1）包括泵部分（2）和流动套管（3）。 流动套管（3）的近端部分（14）连接到泵部分（2），使得血液可以进入血流入口（11），并且流动套管（3）的远端部分 ）包括用于血液进入流动套管（3）的至少一个血液流通开口（16）。 远端部分（13）包括直径扩大部分（15），其中血液流通开口（16）的至少大部分布置在扩大直径部分（15）中。 血泵（1）还包括与扩大直径部分（15）重叠的套筒（4）。 套筒（4）具有防止其远端（42）径向向内弯曲进入血液流通开口（16）的结构。

公开(公告)号：WO2016207293A1

公开(公告)日：2016-12-29

申请号：PCT/EP2016/064562

申请日：2016-06-23

Applicant: ABIOMED EUROPE GMBH

Inventor： SIESS, Thorsten ,  ABOULHOSN, Walid

IPC: A61M1/10 ,  A61M1/12

CPC classification number: A61M1/101 ,  A61M1/1008 ,  A61M1/1012 ,  A61M1/1018 ,  A61M1/1034 ,  A61M1/122 ,  A61M1/125

Abstract: A blood pump (1) comprises a pump casing (2) having a blood flow inlet (21) and a blood flow outlet (22), and an impeller (3) arranged in said pump casing (2) so as to be rotatable about an axis of rotation, wherein the impeller (3) has blades (31) sized and shaped for conveying blood from the blood flow inlet (21) to the blood flow outlet (22). The blood pump (1) further comprises an outflow cannula (4) having an upstream end portion (41), a downstream end portion (43) and an intermediate portion (42) extending between the upstream end portion (41) and the downstream end portion (43). The upstream end portion (41) of the outflow cannula (4) is connected to the pump casing (2) such that blood is conveyed from the blood flow outlet (22) of the pump casing (2) into and through the intermediate portion (42) of the outflow cannula (4) towards the downstream end portion (43) of the outflow cannula (4), wherein the downstream end portion (43) has a blood flow outlet (44) through which blood can exit the outflow cannula (4). At least a portion of the intermediate portion (42) of the outflow cannula (4) has an outer diameter that is larger than an outer diameter of the pump casing (2).

Abstract translation: 血泵（1）包括具有血液流入口（21）和血液流出口（22）的泵壳体（2）和布置在所述泵壳体（2）中的叶轮（3），以便围绕 旋转轴线，其中所述叶轮（3）具有尺寸和形状用于将血液从所述血流入口（21）输送到所述血流出口（22）的叶片（31）。 血泵（1）还包括具有上游端部分（41），下游端部分（43）和在上游端部分（41）和下游端部（41）之间延伸的中间部分（42）的流出套管（4） 部分（43）。 流出套管（4）的上游端部分（41）连接到泵壳体（2），使得血液从泵壳体（2）的血流出口（22）输送到中间部分 （4）的下游端部（43）的流出套管（4）的流体出口（42），其中下游端部（43）具有血液流出口（44） 4）。 流出套管（4）的中间部分（42）的至少一部分的外径大于泵壳体（2）的外径。

公开(公告)号：WO2016001440A1

公开(公告)日：2016-01-07

申请号：PCT/EP2015/065292

申请日：2015-07-06

Applicant: ABIOMED EUROPE GMBH

Inventor： SIESS, Thorsten ,  NIX, Christoph ,  KIRCHHOFF, Frank ,  HUNZIKER, Patrick

IPC: A61M39/02

CPC classification number: A61M39/0247 ,  A61M1/1008 ,  A61M1/101 ,  A61M1/1034 ,  A61M1/122 ,  A61M1/125 ,  A61M39/0606 ,  A61M2039/0258 ,  A61M2039/0267 ,  A61M2039/0273 ,  A61M2039/0279 ,  A61M2039/062 ,  A61M2039/0626 ,  A61M2039/0633 ,  A61M2205/32 ,  A61M2205/3344 ,  A61M2205/6063 ,  A61M2230/30 ,  A61M2230/50

Abstract: A sheath ( 10) for producing a fully sealed access to the interior of a vessel of an animal or human body comprises a base sheath (20) having a tubular body defining a pass-through channel (22). The base sheath (20) is adapted to be inserted into the vessel through a vessel aperture. A wall of the tubular body of the base sheath has a through channel (27). This channel extends in the wall from the distal end (20a) towards the proximal end (20b). The channel (27) can be present separately from the pass-through channel (22) of the base sheath or can form a sideways extension of the pass-through channel (22), at least at the distal end.. Such through channel (27) is adapted to conduct blood from the vessel to the proximal end of the sheath when the sheath has been inserted into a vessel.

Abstract translation: 用于产生对动物或人体的容器内部的完全密封通路的护套（10）包括具有限定穿过通道（22）的管状体的基部护套（20）。 基部护套（20）适于通过血管孔插入血管。 基部护套的管状体的壁具有贯通通道（27）。 该通道从远端（20a）延伸到壁的近端（20b）。 通道（27）可以与基底护套的通过通道（22）分开存在，或者至少在远端处形成通过通道（22）的侧向延伸。这样的通道（ 27）适于在鞘被插入血管时将血液从血管传导到鞘的近端。

公开(公告)号：WO2014057087A1

公开(公告)日：2014-04-17

申请号：PCT/EP2013/071273

申请日：2013-10-11

Applicant: ABIOMED EUROPE GMBH

Inventor： SIEß, Thorsten ,  SPANIER, Gerd

IPC: A61M1/10

CPC classification number: F04D13/027 ,  A61M1/101 ,  A61M1/1012 ,  A61M1/1015 ,  A61M1/1017 ,  A61M1/1029 ,  A61M1/1031 ,  A61M1/122 ,  F04D1/00 ,  F04D7/04 ,  F04D13/06 ,  F04D29/186 ,  F04D29/426 ,  H02K1/2793 ,  H02K3/47

Abstract: A centrifugal blood pump without a mechanical bearing comprises a pump casing (1), an impeller (9) arranged in the pump casing rotatably about the central axis and freely movable axially and radially within a limited clearance. The impeller has permanent magnets or permanently magnetized magnetic regions (N/S) which cooperate with an electromagnetic drive to set the impeller rotating. A circular wall (12) or circularly arranged wall sections are provided within the pump casing, their inner surfaces defining a radial clearance together with the outer circumference of the impeller to form a hydrodynamic radial bearing for the impeller.

Abstract translation: 没有机械轴承的离心式血液泵包括泵壳体（1），叶轮（9），其布置在泵壳体内，围绕中心轴线可旋转并且在有限的间隙内可轴向和径向地自由移动。 叶轮具有与电磁驱动器配合以使叶轮旋转的永磁体或永久磁化磁区（N / S）。 在泵壳体内设置有圆形壁（12）或圆形布置的壁部分，它们的内表面与叶轮的外圆周一起形成径向间隙，以形成用于叶轮的流体动力学径向轴承。

公开(公告)号：WO2022074136A1

公开(公告)日：2022-04-14

申请号：PCT/EP2021/077732

申请日：2021-10-07

Applicant: ABIOMED EUROPE GMBH

Inventor： NIX, Christoph ,  RAJARAM, Mithun ,  ZSCHERLICH, Verena

IPC: A61B5/053 ,  A61B5/0538 ,  A61M60/178 ,  A61M60/165 ,  A61M60/126 ,  A61M25/00 ,  A61B5/00

Abstract: Electrode assembly patches configured for conductance and admittance measurements, and methods of manufacturing same. The present technology provides designs and manufacturing methods that may enable a conductance or admittance electrode assembly patches to be flexible, low-profile, and easily applied to an intravascular blood pump or other device, such that there may be little or no change to the device's overall diameter, profile, and functionality.

公开(公告)号：WO2021191106A1

公开(公告)日：2021-09-30

申请号：PCT/EP2021/057186

申请日：2021-03-22

Applicant: ABIOMED EUROPE GMBH

Inventor： KERKHOFFS, Wolfgang ,  KEYSSELITZ, Ellen

IPC: A61M60/13 ,  A61M60/237 ,  A61M60/422 ,  A61M60/806 ,  A61M60/812 ,  A61M60/824 ,  A61M60/825 ,  A61M60/831

Abstract: This invention relates to an intravascular blood pump (1), comprising a pumping device (11) with a pump section (3) and a drive section (4), wherein the pump section (3) comprises a pump casing (2) having a primary blood flow inlet (211) and a primary blood flow outlet (22) hydraulically connected by a primary passage (30) and the drive section (4) comprises a stator (40) and a rotor (41) rotatable about an axis of rotation (10) and configured to rotate a primary impeller (31), the primary impeller (31 ) being configured to convey a primary blood flow from the primary blood flow inlet (211) to the primary blood flow outlet (22) along the primary passage (30), the drive section (49) further comprises an ancillary blood flow inlet (23) and an ancillary blood flow outlet (24) hydraulically connected by an ancillary passage extending through an axial gap (401) between the rotor (41) and the stator (40) and an ancillary impeller (42) arranged at a drive section end (DSE) of the rotor (41) and rotatable about the axis of rotation (10) along with the rotor, the ancillary impeller (42) comprising one or more ancillary impeller vanes (421) configured to convey an ancillary blood flow (ABF) from the ancillary blood flow inlet (23) to the ancillary blood flow outlet (24) along the ancillary passage in a direction toward a pump section end (PSE) of the pumping device (11), and the rotor (41) is mounted in a blood-purged radial sliding rotor bearing (47) with an inner rotor bearing surface (4211) and an outer rotor bearing surface (4311), and the ancillary impeller (42) forms the inner rotor bearing surface (4211) of the radial sliding rotor bearing (47).