公开(公告)号：WO2017100472A1

公开(公告)日：2017-06-15

申请号：PCT/US2016/065655

申请日：2016-12-08

Applicant: MEDTRONIC VASCULAR INC.

Inventor： TUOHY, John ,  WARD, Sean

IPC: A61M25/01 ,  A61M25/00 ,  A61B90/96 ,  A61B90/00

CPC classification number: A61M25/0023 ,  A61B90/39 ,  A61B90/96 ,  A61B2090/3933 ,  A61B2090/3966 ,  A61M25/0009 ,  A61M25/0108 ,  A61M31/005 ,  A61M2205/32 ,  A61M2205/6072 ,  A61M2207/00 ,  B29C59/16 ,  B29L2031/7543

Abstract: A catheter (100) includes a catheter shaft having a shaft wall and a lumen (135) extending longitudinally within the shaft wall. The lumen is bounded in radially outward and radially inward directions. The lumen includes a feed portion (138) and an identification symbol (140) fluidly connected to the feed portion. The lumen is configured to receive a contrast media. The lumen may be formed by a channel (130) formed in an outer surface of a first shaft (120) of the catheter shaft, and a covering (115) disposed around the outer surface of the first shaft to cover the channel.

Abstract translation: 导管（100）包括具有轴壁和在轴壁内纵向延伸的内腔（135）的导管轴。 内腔沿径向向外和径向向内方向界定。 内腔包括馈送部分（138）和流体连接到馈送部分的识别符号（140）。 内腔配置成接收造影剂。 内腔可以由形成在导管轴的第一轴（120）的外表面中的通道（130）和围绕第一轴的外表面布置以覆盖通道的覆盖物（115）形成。 p>

公开(公告)号：WO2016115571A1

公开(公告)日：2016-07-21

申请号：PCT/US2016013954

申请日：2016-01-19

Applicant: LARSON BARRETT J

Inventor： LARSON BARRETT J

IPC: A61B1/267 ,  A61M16/04 ,  G01R33/07

CPC classification number: A61M16/0488 ,  A61B1/267 ,  A61B5/05 ,  A61B5/4887 ,  A61B5/742 ,  A61B8/085 ,  A61B8/42 ,  A61B8/461 ,  A61M16/0411 ,  A61M2205/0266 ,  A61M2205/0288 ,  A61M2205/32 ,  A61M2205/3317 ,  A61M2205/332 ,  A61M2205/3375 ,  A61M2205/3592 ,  A61M2205/502 ,  A61M2205/587 ,  G01R33/0094 ,  G01R33/07

Abstract: An airway assessment and intubation guidance system, device and method that is portable, simple to use, and effective in reliably locating the trachea within the neck of a wide variety of patients and independent of fluids that may be found within the trachea. The system permits an objective assessment of the likelihood of a difficult intubation, and further provides, depending upon the embodiment, both visual and audible feedback regarding the location of a compatible stylet relative to the trachea.

Abstract translation: 气道评估和插管指导系统，装置和方法，其便携式，易于使用，并且有效地将气管可靠地定位在各种患者的颈部内，并且独立于在气管内可能发现的流体。 该系统允许对难以插管的可能性进行客观评估，并且根据实施例进一步提供关于相对于气管的兼容探针针的位置的视觉和听觉反馈。

公开(公告)号：WO2016097976A1

公开(公告)日：2016-06-23

申请号：PCT/IB2015/059593

申请日：2015-12-14

Applicant: TAMBURINO, Corrado ,  TAMBURINO, Claudia ,  IMME', Sebastiano

Inventor： TAMBURINO, Corrado ,  TAMBURINO, Claudia ,  IMME', Sebastiano

IPC: A61M1/10 ,  A61B17/00 ,  A61F2/24 ,  A61M1/12

CPC classification number: A61M1/125 ,  A61B2017/00575 ,  A61M1/1008 ,  A61M1/101 ,  A61M1/1012 ,  A61M1/1029 ,  A61M1/1037 ,  A61M1/1087 ,  A61M1/122 ,  A61M2205/32 ,  A61M2205/3365 ,  A61M2205/75 ,  A61M2230/005 ,  A61M2230/30

Abstract: A pumping system (200) for controlling the flow of interatrial blood comprises, housed inside a container (201), a control element (30, 30', 30") of the interatrial blood flow. The control element comprises: at least one worm screw (31), the rotation of which creates a two-way flow of interatrial blood; or a pair of counter-rotating propellers (31'); or a pair of membranes (31' ' ) whose deformation creates a two-way flow of interatrial blood; or a flexible structure (31' ' ) whose change in volume within the container (201) creates a two-way flow of interatrial blood.

Abstract translation: 用于控制心房间血液流动的泵送系统（200）包括容纳在容器（201）内的房间血流的控制元件（30,30'，30“）的控制元件，所述控制元件包括：至少一个蠕虫 螺旋（31），其旋转产生间路血液的双向流动;或一对反向旋转螺旋桨（31'）;或一对膜（31“），其变形产生双向流动 的房间内血液;或者容器（201）内体积变化的柔性结构（31“）产生心房间血液的双向流动。

公开(公告)号：WO2016001251A1

公开(公告)日：2016-01-07

申请号：PCT/EP2015/064892

申请日：2015-06-30

Applicant: INTRACAIR IVS

Inventor： CHRISTIANSEN, Karen Juelsgaard ,  KRISTENSEN, Krister Just ,  LARSEN, Henrik Neuschäfer

IPC: A61M16/04

CPC classification number: A61M16/0003 ,  A61M16/04 ,  A61M16/0465 ,  A61M2205/0266 ,  A61M2205/32 ,  A61M2207/00 ,  B29C45/14786 ,  B29L2031/7546

Abstract: A device for sealing a tracheostoma in a patient, comprising a seal member for insertion through the tracheostoma to the trachea, which in a first configuration can form a seal by being pulled against the tracheostoma, and which in a second configuration can be removed from the trachea through the tracheostoma. Preferably, the seal member comprises a disc having a predetermined line of weakness,and a first thread attached to the disc, wherein the disc can be broken along the predetermined line of weakness by pulling the thread. There is also disclosed a kit comprising the device and an external cover, a method of constructing the device,and a method of sealing a tracheostoma in a patient, comprising inserting the sealing member through the tracheostoma into the patient's trachea, and pulling the sealing member to form a seal against the tracheostoma.

Abstract translation: 一种用于密封患者气管切开瘤的装置，包括用于通过气管插管插入气管的密封构件，所述密封构件在第一构造中可以通过被拉向气管瘤而形成密封，并且在第二构造中可以从第二构造中移除 通过气管插管气管。 优选地，密封构件包括具有预定弱线的盘和附接到盘的第一螺纹，其中通过拉动螺纹可以沿着预定的弱线断裂盘。 还公开了一种包括该装置和外部盖的套件，一种构造该装置的方法以及一种密封患者气管瘤的方法，包括将所述密封构件通过气管插管插入病人的气管中，并且将所述密封构件 形成针对气管插管的密封。

公开(公告)号：WO2015013381A1

公开(公告)日：2015-01-29

申请号：PCT/US2014/047772

申请日：2014-07-23

Applicant: MEDICAL INSTRUMENT VENTURES, LLC

Inventor： LEDGES, Matthew ,  FALLON, Mike

IPC: A61B19/00 ,  A61M16/00 ,  A61M16/04

CPC classification number: A61M16/04 ,  A61B2090/3925 ,  A61M16/0445 ,  A61M16/0459 ,  A61M2205/0205 ,  A61M2205/0238 ,  A61M2205/32

Abstract: An endotracheal tube assembly for intubating a patient including a rolling cuff positionable on a tube having a distal end and a proximal end. The rolling cuff having a distal end, a proximal end, an inner diameter forming a first elongated tubular section substantially adjacent to the tube, and an outer diameter forming a second elongated tubular section. The rolling cuff being positioned towards the distal end of the tube. The rolling cuff including a single attachment portion for attaching a portion of the first elongated tubular section to the tube, wherein the single attachment portion allows the rolling cuff to roll from the distal end of the tube towards the proximal end of the tube to expose an ultrasound imaging marker disposed on the first elongated tubular section.

Abstract translation: 一种用于插管患者的气管内管组件，包括可定位在具有远端和近端的管上的滚动箍。 所述滚动箍具有远端，近端，形成基本上邻近管的第一细长管状部分的内径和形成第二细长管状部分的外径。 滚动的套囊朝向管的远端定位。 所述滚动箍具有用于将所述第一细长管状部分的一部分附接到所述管的单个附接部分，其中所述单个附接部分允许所述滚动箍从所述管的远端朝向所述管的近端滚动以暴露 设置在第一细长管状部分上的超声成像标记。

公开(公告)号：WO2014184358A2

公开(公告)日：2014-11-20

申请号：PCT/EP2014/060117

申请日：2014-05-16

Applicant: FISCHER, Georg

Inventor： FISCHER, Georg

IPC: A61M5/168

CPC classification number: A61M5/14526 ,  A61M5/14276 ,  A61M5/16831 ,  A61M5/16854 ,  A61M5/16877 ,  A61M39/221 ,  A61M39/24 ,  A61M2005/14284 ,  A61M2005/16863 ,  A61M2205/16 ,  A61M2205/18 ,  A61M2205/32 ,  A61M2205/581 ,  A61M2205/582

Abstract: The present invention provides an emergency supply valve to support the in situ administration of a drug to a subject in need thereof, comprising an infusion needle connected to a movable piston, wherein said piston is forwarded by infusion solution unable to pass the regular drug line due to kinking or obstruction thereof, a self-sealing membrane that is disrupted by the infusion needle when the piston is in a forward position, a connecting unit that connects the needle to the regular drug conduit when the needle is in a forward position, and a pressure sensitive mechanism that retracts the piston from the forward position when an increased pressure of the drug supply is normalized and its use for the treatment of subjects in need thereof.

Abstract translation: 本发明提供了一种紧急供应阀，用于支持药物到有需要的受试者的原位给药，其包括连接到可移动活塞的输注针，其中所述活塞由输注溶液输送不能通过正常药物线 使其弯曲或阻塞，当活塞处于向前位置时由输注针中断的自密封膜，当针处于向前位置时将针连接到正常药物导管的连接单元，以及 压力敏感机构，当药物供应的压力增加被标准化时，将活塞从前进位置缩回，并且其用于治疗有需要的受试者。

公开(公告)号：WO2014116640A1

公开(公告)日：2014-07-31

申请号：PCT/US2014/012449

申请日：2014-01-22

Applicant: ALCYONE LIFESCIENCES, INC.

Inventor： ANAND, Pj ,  SINGH, Deep, Arjun ,  BROPHY, Morgan ,  FALLON, Timothy ,  DEGON, Robert ,  ATTAR, Matthew ,  WONG, Anthony ,  WALLER, Allison ,  EAST, Andrew ,  MCINTYRE, Jon, T.

IPC: A61M25/14 ,  A61B17/22 ,  A61B18/24

CPC classification number: A61M27/006 ,  A61M39/225 ,  A61M2025/0019 ,  A61M2039/0018 ,  A61M2205/0205 ,  A61M2205/32 ,  A61M2205/3344 ,  A61M2230/20

Abstract: Systems and methods are provided herein that generally involve shunting fluid, e.g., shunting cerebrospinal fluid in the treatment of hydrocephalus. Self-cleaning catheters are provided which include split tips configured such that pulsatile flow of fluid in a cavity in which the catheter is inserted can cause the tips to strike one another and thereby clear obstructions. Catheters with built-in flow indicators are also provided. Exemplary flow indicators include projections that extend radially inward from the interior surface of the catheter and which include imageable portions (e.g., portions which are visible under magnetic resonance imaging (MRl)). Movement of the flow indicators caused by fluid flowing through the catheter can be detected using MRl, thereby providing a reliable indication as to whether the catheter is partially or completely blocked. Systems and methods for flushing a shunt system and for opening auxiliary fluid pathways through a shunt system are also disclosed herein.

Abstract translation: 本文提供的系统和方法通常涉及分流流体，例如在治疗脑积水时分流脑脊液。 提供了自清洁导管，其包括分开的尖端，其被配置为使得在其中插入导管的空腔中的脉动流动可导致尖端彼此撞击，从而清除障碍物。 还提供了内置流量指示器的导管。 示例性流量指示器包括从导管的内表面径向向内延伸并且包括可成像部分（例如在磁共振成像（MR1）下可见的部分））的突起。 可以使用MR1检测由流体流过导管引起的流动指示器的运动，从而提供关于导管是部分地还是完全阻塞的可靠指示。 本文还公开了用于冲洗分流系统和用于打开通过分流系统的辅助流体路径的系统和方法。

公开(公告)号：WO2014028787A2

公开(公告)日：2014-02-20

申请号：PCT/US2013055221

申请日：2013-08-15

Applicant: NOVITA THERAPEUTICS ,  FRANANO F NICHOLAS ,  LOREE II HOWARD M ,  TANSLEY GEOFF ,  WOODARD STEVE ,  HUTTO BARRETT

Inventor： FRANANO F NICHOLAS ,  LOREE II HOWARD M ,  TANSLEY GEOFF ,  WOODARD STEVE ,  HUTTO BARRETT

IPC: A61M1/10

CPC classification number: A61M1/3653 ,  A61M1/1008 ,  A61M1/101 ,  A61M1/1012 ,  A61M1/1013 ,  A61M1/1015 ,  A61M1/1017 ,  A61M1/1031 ,  A61M1/1086 ,  A61M1/12 ,  A61M1/122 ,  A61M1/3655 ,  A61M1/3659 ,  A61M2205/32 ,  A61M2205/3334 ,  A61M2205/3344

Abstract: The present invention relates to a rotary blood pump with a double pivot contact bearing system with an operating range between about 50 mL/min and about 1500 mL/min, wherein the force on the upper bearing is less than 3N during operating speeds up to 6000 rpm. The rotary blood pump is part of a blood pump system that includes blood conduit(s), a control system with optional sensors, and a power source. Embodiments of the present invention may include elements designed to increase the length of time the rotary blood system can operate effectively in vivo, including wear resistant bearing materials, a rotor back plate for magnetic attraction of the rotor to reduce bearing pivot bearing forces and wear, a rotor size and shape and a bearing gap that combine to create a hydrodynamic bearing effect and reduce bearing pivot bearing forces and wear, improved intravascular conduits with increased resistance to thrombosis, conduit insertion site cuffs to resist infection, and conduit side ports amenable to the easy insertion of guidewire and catheter-based medical devices to treat conduits and related blood vessels to maintain blood pump system function over time. The pump system is configured to connect to the vascular system in a patient and pump blood at a desired rate. The invention also relates to a method of using a blood pump system for persistently increasing the overall diameter and lumen diameter of peripheral veins and arteries by persistently increasing the velocity of blood and the wall shear stress in a peripheral vein or artery for period of time sufficient to result in a persistent increase in the overall diameter and lumen diameter of the vessel is provided. For blood pump systems intended for use to increase the overall diameter and lumen diameter of a blood vessel, the pumping of blood is monitored and adjusted, as necessary, to maintain the desired elevated blood velocity and wall shear stress, and the desired pulsatility in the target blood vessel in order to optimize the rate and extent of the persistent increase in the overall diameter and lumen diameter of the target blood vessel. The blood pump system may also be used to reduce venous hypertension in a lower extremity and increasing the rate of healing of lower extremity venous ulcers in patients is provided. For blood pump systems intended for use to treat venous hypertension of an extremity, the pumping of blood is monitored and adjusted, as necessary, to maintain the desired venous blood pressure in the treated extremity.

Abstract translation: 本发明涉及具有约50mL / min至约1500mL / min的操作范围的双重枢轴接触轴承系统的旋转式血液泵，其中在高达6000的操作速度下，上轴承上的力小于3N 转。 旋转式血液泵是血液泵系统的一部分，其包括血液导管，具有可选传感器的控制系统和电源。 本发明的实施例可以包括设计用于增加旋转血液系统在体内有效操作的时间长度的元件，包括耐磨轴承材料，用于转子磁吸引以减少轴承枢转轴承力和磨损的转子后板， 转子尺寸和形状以及轴承间隙，其组合以产生流体动力轴承效应并减少轴承枢转轴承力和磨损，改善的血管内管道具有增加的抗血栓形成，导管插入部位袖带以抵抗感染，以及导管侧端口适于 容易地插入导丝和基于导管的医疗装置来治疗导管和相关的血管以维持血液泵系统随时间的功能。 泵系统被配置为连接到患者中的血管系统并以期望的速率泵血。 本发明还涉及一种使用血液泵系统持续增加外周静脉和动脉的总直径和内腔直径的方法，其通过持续增加外周静脉或动脉中的血液速度和壁剪切应力足够长的时间 导致容器的总直径和管腔直径的持续增加。 对于旨在用于增加血管的总直径和管腔直径的血泵系统，根据需要监测和调节血液的泵送，以保持所需的升高的血液速度和壁剪切应力，以及所需的搏动 目标血管，以优化目标血管总直径和内腔直径持续增加的速度和程度。 血泵系统也可用于减少下肢静脉高血压，提高患者下肢静脉溃疡愈合率。 对于旨在用于治疗肢体静脉高血压的血液泵系统，根据需要监测和调整血液的抽吸，以在治疗的末端保持所需的静脉血压。

公开(公告)号：WO2013070829A1

公开(公告)日：2013-05-16

申请号：PCT/US2012/064036

申请日：2012-11-08

Applicant: TELEFLEX MEDICAL INCORPORATED

Inventor： ROTH, Gary, James

IPC: A61M16/04

CPC classification number: A61M16/0463 ,  A61M16/04 ,  A61M16/0431 ,  A61M16/0434 ,  A61M16/0479 ,  A61M16/0486 ,  A61M2205/32 ,  F04C2270/0421

Abstract: The present invention provides in some embodiments, an endotracheal tube with subglottic secretion suction and a detachable suction line. The endotracheal tube (10) is an elongate tube having an outer wall (12) defining an elongate central lumen (14) and an elongate suction lumen (16). The outer wall also defines an opening (42) to the suction lumen near a distal end of the endotracheal tube. An inflatable cuff (26) is attached near a distal end (18) of the elongate tube. The shoulder of the inflatable cuff is inverted in order to increase the diameter of the cuff from its distal end (50) to its proximal end (44). A diffuser cap (41) is positioned over the opening to the suction lumen and defines a fluid flow path for secretions into the suction lumen through the opening to the suction lumen.

Abstract translation: 本发明在一些实施例中提供具有声门下分泌吸力的气管内管和可拆卸的吸入管线。 气管内管（10）是具有限定细长中心腔（14）和细长抽吸腔（16）的外壁（12）的细长管。 外壁还在气管内管的远端附近限定到吸入腔的开口（42）。 可充气袖带（26）附接在细长管的远端（18）附近。 可充气袖带的肩部被倒置，以便将袖带的直径从其远端（50）增加到其近端（44）。 扩散器盖（41）位于吸入腔的开口上方，并且通过穿过吸入腔的开口限定用于分泌物进入吸入腔的流体流动路径。

公开(公告)号：WO2013002866A2

公开(公告)日：2013-01-03

申请号：PCT/US2012/032547

申请日：2012-04-06

Applicant: SALIENT SURGICAL TECHNOLOGIES, INC. ,  BLOOM, Eliot, Frank ,  EARLES, Donald

Inventor： BLOOM, Eliot, Frank ,  EARLES, Donald

IPC: A61M16/04 ,  A61M25/00

CPC classification number: A61M16/0816 ,  A61M16/0418 ,  A61M16/0434 ,  A61M16/0463 ,  A61M16/0484 ,  A61M16/0486 ,  A61M16/0488 ,  A61M16/0833 ,  A61M25/0032 ,  A61M25/0041 ,  A61M25/0097 ,  A61M25/04 ,  A61M2025/0037 ,  A61M2025/0175 ,  A61M2205/32 ,  A61M2205/3375 ,  A61M2205/583 ,  A61M2205/6045

Abstract: A catheter system can include a first catheter including a first proximal end portion and a lumen. The first proximal end portion has a first key joint component that extends along a partial length of the first proximal end portion. The catheter system can also include a second catheter including a second key joint component that corresponds with the first key joint component. The first key joint component and the second key joint component are configured to be coupled together when the second catheter is slidably disposed within the lumen of the first catheter such that a rotational orientation of the second catheter is fixed relative to a rotational orientation of the first catheter. The first proximal end portion can be a fitting, and the first key joint component can include an opening defined by the fitting.

Abstract translation: 导管系统可以包括第一导管，其包括第一近端部分和内腔。 第一近端部分具有沿第一近端部分的部分长度延伸的第一键接头部件。 导管系统还可以包括第二导管，第二导管包括与第一钥匙接头部件对应的第二钥匙接头部件。 第一钥匙接头部件和第二钥匙接头部件构造成当第二导管可滑动地设置在第一导管的内腔内时连接在一起，使得第二导管的旋转取向相对于第一导管的旋转取向固定 导管。 第一近端部分可以是配件，并且第一关键连接部件可以包括由配件限定的开口。