公开(公告)号：WO2016196199A1

公开(公告)日：2016-12-08

申请号：PCT/US2016/034339

申请日：2016-05-26

Applicant: AJJER, LLC

Inventor： AGRAWAL, Anoop ,  ADAMS, Lori, L. ,  CRONIN, John, P.

IPC: G01N21/64 ,  G01J3/30 ,  G01N33/18 ,  G01N33/24

CPC classification number: G01N21/6428 ,  G01N21/643 ,  G01N33/18 ,  G01N33/24

Abstract: A method of determining beryllium or a beryllium compound thereof in a sample is disclosed by measuring fluorescence. This method discloses use of highly alkaline fluorescent indicating dye solutions with pH greater than 12.9. In a preferred embodiment the fluorescent indicating dye solutions do not contain a pH buffer. Further, the method also discloses measuring fluorescence under highly alkaline conditions, where the pH after mixing the highly alkaline fluorescent indicating dye solutions with the sample solution containing beryllium is at least 11, preferably 12. The use of highly alkaline solution provides superior detection limits for beryllium by using dilution ratios of 4X and lower.

Abstract translation: 通过测量荧光来公开测定样品中铍或其铍化合物的方法。 该方法公开了使用pH大于12.9的高碱性荧光显示染料溶液。 在优选的实施方案中，荧光指示染料溶液不含有pH缓冲液。 此外，该方法还公开了在高碱性条件下测量荧光，其中将高碱性荧光指示染料溶液与含有铍的样品溶液混合后的pH为至少11，优选为12。使用高碱性溶液提供了优异的检测限 铍通过使用4X以下的稀释比。

公开(公告)号：WO2009117032A3

公开(公告)日：2009-12-30

申请号：PCT/US2008087498

申请日：2008-12-18

Applicant: AJJER LLC ,  AGRAWAL ANOOP ,  TONAZZI JUAN CARLOS L ,  ADAMS LORI L ,  CRONIN JOHN P

Inventor： AGRAWAL ANOOP ,  TONAZZI JUAN CARLOS L ,  ADAMS LORI L ,  CRONIN JOHN P

IPC: G01N33/20

CPC classification number: G01N21/6452 ,  B01L3/0293 ,  B01L3/50255 ,  B01L2200/0689 ,  B01L2300/046 ,  B01L2300/0829 ,  G01N21/6428 ,  G01N33/24

Abstract: Use of high throughput methods to analyze samples for toxic elements originating from industrial hygiene and environmental sampling are described. These methods utilize optical detection methods using plates with arrays and microwells. Methods to fabricate samples in such plates are described. The invention is particularly illustrated by demonstrating its applicability for analysis of beryllium by fluorescence. This invention also discloses the use of improved filtration method compatible with the high throughput methods of sample preparation and analysis.

Abstract translation: 描述了使用高通量方法分析来自工业卫生和环境取样的有毒元素的样品。 这些方法利用具有阵列和微孔的板的光学检测方法。 描述在这种板中制造样品的方法。 通过证明其通过荧光分析铍的适用性来特别说明本发明。 本发明还公开了使用与样品制备和分析的高通量方法兼容的改进的过滤方法。

公开(公告)号：WO2010003138A1

公开(公告)日：2010-01-07

申请号：PCT/US2009/049644

申请日：2009-07-02

Applicant: AJJER LLC ,  AGRAWAL, Anoop ,  CRONIN, John, P. ,  ADAMS, Lori, L. ,  TONAZZI, Juan, Carlos, L.

Inventor： AGRAWAL, Anoop ,  CRONIN, John, P. ,  ADAMS, Lori, L. ,  TONAZZI, Juan, Carlos, L.

IPC: G02F1/01

CPC classification number: G02F1/163 ,  G02F1/1506 ,  G02F1/1508 ,  G02F1/1533 ,  G02F1/155 ,  G02F1/161 ,  G02F2001/1515 ,  Y10T29/49155

Abstract: This invention discloses how EC devices can be fabricated as tags or labels; and further the materials used, device structures and how these can be processed by printing technologies. In addition, systems using displays of such EC devices and their integration with other components are described for forming labels and tags, etc, that may be actuated wirelessly or powered with low voltage and low capacity batteries.

Abstract translation: 本发明公开了如何将EC装置制造成标签或标签; 并进一步使用材料，设备结构以及如何通过印刷技术处理这些材料。 此外，描述了使用这种EC装置的显示器及其与其他部件的集成的系统，用于形成可以无线地致动或用低电压和低容量电池供电的标签和标签等。

公开(公告)号：WO2009117032A2

公开(公告)日：2009-09-24

申请号：PCT/US2008/087498

申请日：2008-12-18

Applicant: AJJER LLC ,  AGRAWAL, Anoop ,  TONAZZI, Juan, Carlos L. ,  ADAMS, Lori, L. ,  CRONIN, John, P.

Inventor： AGRAWAL, Anoop ,  TONAZZI, Juan, Carlos L. ,  ADAMS, Lori, L. ,  CRONIN, John, P.

IPC: G01N33/20

CPC classification number: G01N21/6452 ,  B01L3/0293 ,  B01L3/50255 ,  B01L2200/0689 ,  B01L2300/046 ,  B01L2300/0829 ,  G01N21/6428 ,  G01N33/24

Abstract: Use of high throughput methods to analyze samples for toxic elements originating from industrial hygiene and environmental sampling are described. These methods utilize optical detection methods using plates with arrays and microwells. Methods to fabricate samples in such plates are described. The invention is particularly illustrated by demonstrating its applicability for analysis of beryllium by fluorescence. This invention also discloses the use of improved filtration method compatible with the high throughput methods of sample preparation and analysis.

Abstract translation: 描述了使用高通量方法来分析样品中源自工业卫生和环境取样的有毒元素。 这些方法利用使用具有阵列和微孔板的光学检测方法。 描述了在这种板中制造样品的方法。 通过证明其通过荧光分析铍的适用性来具体说明本发明。 本发明还公开了使用与样品制备和分析的高通量方法兼容的改进的过滤方法。

公开(公告)号：WO2008130737A1

公开(公告)日：2008-10-30

申请号：PCT/US2008/055558

申请日：2008-02-29

Applicant: AJJER LLC ,  AGRAWAL, Anoop ,  CRONIN, John, P. ,  TONAZZI, Juan, Carlos, L.

Inventor： AGRAWAL, Anoop ,  CRONIN, John, P. ,  TONAZZI, Juan, Carlos, L.

IPC: C12M3/00

CPC classification number: G01N21/643

Abstract: An improved low-cost practical method of determining beryllium or a beryllium compound thereof in a sample is disclosed by measuring fluorescence. This method discloses methods to lower the back ground fluorescence. Further, the method is extended to improved analysis of beryllium in soils by including a heating step.

Abstract translation: 通过测量荧光公开了一种改进的低成本实施方法来测定样品中的铍或其铍化合物。 该方法公开了降低背景荧光的方法。 此外，该方法通过包括加热步骤来扩展到对铍中的铍的改进分析。