公开(公告)号：WO2004078116A3

公开(公告)日：2004-09-16

申请号：PCT/US2004/005693

申请日：2004-02-25

Applicant: ARRAY BIOPHARMA, INC. ,  MUNSON, Mark ,  MARESKA, David, A. ,  KIM, Youngboo ,  GRONEBERG, Robert ,  RIZZI, James ,  RODRIGUEZ, Martha ,  KIM, Ganghyeok ,  VIGERS, Guy ,  RAO, Chang ,  BALACHARI, Devan ,  HARVEY, Darren

Inventor： MUNSON, Mark ,  MARESKA, David, A. ,  KIM, Youngboo ,  GRONEBERG, Robert ,  RIZZI, James ,  RODRIGUEZ, Martha ,  KIM, Ganghyeok ,  VIGERS, Guy ,  RAO, Chang ,  BALACHARI, Devan ,  HARVEY, Darren

IPC: A61K31/4745 ,  A61K31/503 ,  A61K31/675 ,  C07D401/14 ,  C07D471/02 ,  C07D487/02

Abstract: This invention relates to inhibitors of p38, and methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing the inhibitors and pharmaceutical compositions in the treatment and prevention of various disorders mediated by p38.

公开(公告)号：WO2004078116A2

公开(公告)日：2004-09-16

申请号：PCT/US2004005693

申请日：2004-02-25

Applicant: ARRAY BIOPHARMA INC ,  MUNSON MARK ,  MARESKA DAVID A ,  KIM YOUNGBOO ,  GRONEBERG ROBERT ,  RIZZI JAMES ,  RODRIGUEZ MARTHA ,  KIM GANGHYEOK ,  VIGERS GUY ,  RAO CHANG ,  BALACHARI DEVAN ,  HARVEY DARREN

Inventor： MUNSON MARK ,  MARESKA DAVID A ,  KIM YOUNGBOO ,  GRONEBERG ROBERT ,  RIZZI JAMES ,  RODRIGUEZ MARTHA ,  KIM GANGHYEOK ,  VIGERS GUY ,  RAO CHANG ,  BALACHARI DEVAN ,  HARVEY DARREN

IPC: A61K20060101 ,  A61K31/4745 ,  A61K31/503 ,  A61K31/675 ,  C07D20060101 ,  C07D231/56 ,  C07D261/20 ,  C07D401/14 ,  C07D403/04 ,  C07D413/12 ,  C07D471/02 ,  C07D471/04 ,  C07D487/02 ,  C07D491/02 ,  A61K

CPC classification number: C07D471/04 ,  C07D231/56 ,  C07D261/20 ,  C07D413/12

Abstract: This invention relates to inhibitors of p38, and methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing the inhibitors and pharmaceutical compositions in the treatment and prevention of various disorders mediated by p38.

Abstract translation: 本发明涉及p38的抑制剂及其制备方法。 本发明还提供包含本发明抑制剂的药物组合物和利用抑制剂和药物组合物治疗和预防由p38介导的各种疾病的方法。

公开(公告)号：WO2004078116A9

公开(公告)日：2008-09-12

申请号：PCT/US2004005693

申请日：2004-02-25

Applicant: ARRAY BIOPHARMA INC ,  MUNSON MARK ,  MARESKA DAVID A ,  KIM YOUNGBOO ,  GRONEBERG ROBERT ,  RIZZI JAMES ,  RODRIGUEZ MARTHA ,  KIM GANGHYEOK ,  VIGERS GUY ,  RAO CHANG ,  BALACHARI DEVAN ,  HARVEY DARREN

Inventor： MUNSON MARK ,  MARESKA DAVID A ,  KIM YOUNGBOO ,  GRONEBERG ROBERT ,  RIZZI JAMES ,  RODRIGUEZ MARTHA ,  KIM GANGHYEOK ,  VIGERS GUY ,  RAO CHANG ,  BALACHARI DEVAN ,  HARVEY DARREN

IPC: A61K31/4745 ,  A61K20060101 ,  A61K31/503 ,  A61K31/675 ,  C07D20060101 ,  C07D231/56 ,  C07D261/20 ,  C07D401/14 ,  C07D403/04 ,  C07D413/12 ,  C07D471/02 ,  C07D471/04 ,  C07D487/02 ,  C07D491/02

CPC classification number: C07D471/04 ,  C07D231/56 ,  C07D261/20 ,  C07D413/12

Abstract: This invention relates to inhibitors of p38, and methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing the inhibitors and pharmaceutical compositions in the treatment and prevention of various disorders mediated by p38.

Abstract translation: 本发明涉及p38的抑制剂及其制备方法。 本发明还提供包含本发明抑制剂的药物组合物和利用抑制剂和药物组合物治疗和预防由p38介导的各种疾病的方法。