Abstract:
Devices and systems are disclosed herein. One aspect of the present technology is directed to biomarker sampling in the context of neuromodulation devices and systems. Some embodiments, for example, are directed to catheters and catheter systems for sampling biomarkers that change in response to neuromodulation. A system can include, for example, an elongated shaft and a neuromodulation and sampling assembly having a neuromodulation and a sampling element.
Abstract:
Methods for treating a patient using therapeutic renal neuromodulation and associated devices, systems, and methods are disclosed herein. One aspect of the present technology is directed to biomarker sampling in the context of neuromodulation devices, systems, and methods. Some embodiments, for example, are directed to catheters, catheter systems, and methods for sampling biomarkers that change in response to neuromodulation. A system can include, for example, an elongated shaft and a neuromodulation and sampling assembly having a neuromodulation and a sampling element.
Abstract:
An inner member for use within a stent delivery system is provided, wherein the stent delivery system has a stent and a balloon disposed within the stent, the balloon configured to be mounted about the inner member in a collapsed state. The inner member comprises a proximal section, a distal section, and an intermediate section. The proximal and distal sections each have a first outer diameter. The proximal and distal sections have a first and a second lumen therethrough, respectively. The intermediate section having a third lumen therethrough in communication with the first and second lumens and has a second outer diameter larger than the first outer diameter for exerting a retaining force on the stent.
Abstract:
An implantable medical device (10), such as a sensor for monitoring a selected internally detectable physiological parameter of a patient, is attached to a fixation member (30) that is deployable within the patient to position and orient the sensor to enable it to perform its function. The fixation member is be configured to lie in a single plane when deployed and coprises one or more loops (42). The attachment of the housing and fixation member includes providing the fixation member with a linear attachment strut (44) that is non-circular in cross section and providing the housing with external members (46-48) that define an elongate channel, non-circular in cross section and receptive to the attachment strut. The attachment strut can be inserted transversely into the channel and the external member can be crimped over the strut to secure the housing and fixation member together.
Abstract:
An implantable sensor assembly (108) comprises a sensor housing (26) with sensor means for monitoring a selected internally detectable physiological parameter of a patient, the sensor housing being attached to a fixation member (110) that is deployable within the patient to position and orient the sensor means to enable it to perform its function. The fixation member may be configured to lie in a single plane when deployed or may be tubular in shape. The fixation member includes a linear attachment strut (116) that is non-circular in cross section whereas the housing is provided with external members that define an elongate channel, non-circular in cross section and receptive to the attachment strut. The attachment strut is inserted transversely into the channel and one of the external members is crimped over the strut to secure the housing and the fixation member together.