公开(公告)号：WO2016192063A1

公开(公告)日：2016-12-08

申请号：PCT/CN2015/080717

申请日：2015-06-03

申请人： CHANGZHOU JIEKAI PHARMATECH CO. LTD ,  JS INNOPHARM (SHANGHAI) LTD

发明人： ZHANG, Jintao ,  XU, Wen ,  JIAN, Shanzhong

IPC分类号： C07D487/04 ,  A61K31/4745 ,  A61P35/00

CPC分类号： C07D487/04 ,  A61P35/00 ,  C07D519/00

摘要： Disclosed herein is a compound of formula (I) and/or a pharmaceutically acceptable salt thereof that can serve as Erk inhibitors. They are potentially useful in the treatment of diseases treatable by inhibition of Erk, such as cancers. Also disclosed herein is a pharmaceutical composition comprising a compound of formula (I) and/or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable carrier.

摘要翻译： 本文公开了可用作Erk抑制剂的式（I）化合物和/或其药学上可接受的盐。 它们可用于治疗通过抑制Erk可治疗的疾病，例如癌症。 本文还公开了包含式（I）化合物和/或其药学上可接受的盐和药学上可接受的载体的药物组合物。