摘要:
The present invention relates to a light-stabilized composition comprising at least one polymer and 0.01 to 25 % by weight, based on the total weight of the composition, of a light-stabilizing component comprising at least one heptaazaphenalene compound of general formula (I), wherein the radicals R 1 , R 2 and R 3 are defined in the description, optionally in combination with at least one further light stabilizer (Z), articles, moulds, sheets, foils or films produced of such light-stabilized composition, the use of at least one heptaazaphenalene compound of general formula (I) as a light stabilizer for polymers as well as to a light stabilizer combination comprising at least one of said heptaazaphenalene and at least one further light-stabilizer (Z).
摘要:
The present invention refers to a combination of at least 2 UV-absorbing active substances (A) and (B), wherein the UV-absorbing active substance (A) is at least one pyrrolyltriazine compound of the general formula (I) which is defined as hereinafter and which has its absorption maximum λ max in the range of UV-A or UV-B radiation, in combination with at least one UV-absorbing active substance (B), which has its absorption maximum λ max(B) in the range of UV-A or UV-B radiation, preferably in such UV radiation range in which the λ max(A) of UV-absorbing active substance (A) does not lie, and wherein the ratio of the molar extinction coefficient at λ max [ε λmax(A) ] of the UV-absorbing active substance (A) to the molar extinction coefficient at λ max [ε λmax(B) ] of the UV-absorbing active substance (B) is from 1:10 to 20:1, to a pharmaceutical or a cosmetical composition comprising said combination, to the use of a combination of said active substances for the production of a medicament for the prophylaxis of diseases caused by and/or associated with exposure to ultraviolet radiation and the to use of a combination of active substances for protecting the skin of mammals, as a photostabilizer combination additive or as a component of textile fibers.
摘要:
The invention relates to compounds having pharmacological activity towards the sigma receptor, and more particularly to pyrazole derivatives of formula (I) and to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use therapy and prophylaxis, in particular for the treatment of psychosis or pain.
摘要:
The present invention refers to a combination of at least 2 UV-absorbing active substances (A) and (B), wherein the UV-absorbing active substance (A) is at least one heptaazaphenalene compound of the general formula (I), which is defined in the description and the UV-absorbing active substance (B) is at least one compound which has its absorption maximum λ maX(B) in the range of UV-A or UV-B radiation.
摘要:
The present invention relates to compounds having pharmacological activity towards the sigma (σ) receptor, and more particularly to some 4, 5, 6, 7 tetrahydrobenzo[b]thiophene derivatives, wherein n is selected from 0, 1, 2, 3 or 4; m is selected from 0, 1 or 2; the dotted line represents either a single or a double bond; to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy and prophylaxis, in particular for the treatment of psychosis.
摘要:
The present invention relates to new pyrazolo[3,4- d ]pyrimidine compounds having a great affinity for sigma receptors, especially sigma-1 receptors as well as to the process for the preparation thereof, to composition comprising them and to their use as medicaments.
摘要:
The invention relates to compounds having pharmacological activity towards the sigma receptor, and more particularly to indazole derivatives of formula I and to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use therapy and/or prophylaxis, in particular for the treatment of psychosis or pain.
摘要:
The present invention relates to new compounds of general Formula (I), where R 1 is a ring system containing C and N, being at least one of them different from C; optionally being substituted; R 2 and R 2 ' are radicals, same or different, independently selected from linear or branched (C 1 -C 4 )alkyl, and - O-(C 1 -C 4 )alkyl; R 3 and R 3 ' are radicals, same or different, independently selected from hydrogen, (C- 1 -C- 18 )acyl radical, linear or branched (C- 1 -C- 18 )alkyl, and linear or branched (C 2 -C- 18 )alkenyl; wherein the radical is optionally substituted. The physicochemical properties of said compounds allow them to be used as protecting agents against UV radiation.
摘要:
The present invention relates to compounds of formula (I), methods for their preparation, medicaments comprising these compounds as well their use in the manufacture of a medicament for the treatment of humans and animals.
摘要:
The invention relates to compounds having pharmacological activity towards the sigma receptor, and more particularly to indazole derivatives of formula I and to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use therapy and/or prophylaxis, in particular for the treatment of psychosis or pain.