公开(公告)号：WO2010101528A1

公开(公告)日：2010-09-10

申请号：PCT/SG2010/000072

申请日：2010-03-02

Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH ,  DESAI, Kartik, V ,  LIU, Edison T ,  MILLER, Lance, David

Inventor： DESAI, Kartik, V ,  LIU, Edison T ,  MILLER, Lance, David

IPC: C12Q1/68 ,  A61K39/395 ,  C07K16/28 ,  C07K16/30 ,  C12N15/113

CPC classification number: C07K16/3015 ,  C07K16/40 ,  C12N9/00 ,  C12N9/0071 ,  C12N15/1135 ,  C12N15/1137 ,  C12N2310/14 ,  C12Q1/6886 ,  C12Q2600/112 ,  C12Q2600/118 ,  C12Q2600/136 ,  C12Q2600/154 ,  C12Q2600/158 ,  C12Q2600/178 ,  C12Y114/11004 ,  G01N33/573 ,  G01N33/57415 ,  G01N33/57496

Abstract: A correlation between expression of JMJD6 polypeptide and breast cancer metastasis exists accordingly the present invention relates a diagnostic, prognostic and therapeutic biomarker to distinguish between early and advanced/metastatic cancer particularly breast cancer, including compounds and methods to treat the same.

Abstract translation: 因此，JMJD6多肽的表达与乳腺癌转移之间的相关性存在，因此本发明涉及诊断，预后和治疗性生物标志物，以区分早期/晚期/转移性癌症，特别是乳腺癌，包括化合物和治疗它们的方法。