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公开(公告)号：WO2017149450A2
公开(公告)日：2017-09-08
申请号：PCT/IB2017/051164
申请日：2017-02-28
Applicant: DR. REDDYS LABORATORIES
Inventor： SHARMA, Ketan , DHUNDI, Ritesh M , SRIVASTAVA, Shitanshu
IPC: B01D15/08
CPC classification number: B01D15/08 , B01D15/163 , G01N30/32 , G01N30/86 , G01N30/88 , G01N2030/889
Abstract: The present invention relates to the field of preparative chromatography. The invention provides a rapid method to assess the chromatographic column lifetime during a preparative scale chromatography. The method specifically measures the difference in the column back pressures obtained at two different flow rates, during the cleaning step of a chromatographic process, to assess the re-usability or lifetime of the resin/matrix.
Abstract translation: 本发明涉及制备色谱领域。 本发明提供了一种评估制备级色谱过程中色谱柱寿命的快速方法。 该方法具体测量在色谱过程的清洁步骤期间在两种不同流速下获得的柱背压差，以评估树脂/基质的可再使用性或寿命。
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2.发明申请
公开(公告)号：WO2015011659A1
公开(公告)日：2015-01-29
申请号：PCT/IB2014/063346
申请日：2014-07-23
Applicant: DR. REDDYS LABORATORIES LIMITED
Inventor： IQBAL, Javed , ORUGANTI, Sreenivas , RAPOLU, Rajesh Kumar , KANNIAH, Sundara Lakshmi , PEDDY, Vishweshwar , CHENNURU, Ramanaiah
IPC: A61K31/675 , C07D213/81
CPC classification number: C07D213/81
Abstract: The present application relates to the novel crystalline polymorphic form A, B, C and D of Regorafenib and processes thereof. The present application also relates to the processes for the preparation of polymorph I of Regorafenib.
Abstract translation: 本申请涉及Regorafenib的新型结晶多晶型A，B，C和D及其过程。 本申请还涉及制备雷卡非尼多晶型I的方法。
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公开(公告)号：WO2014174456A2
公开(公告)日：2014-10-30
申请号：PCT/IB2014/060935
申请日：2014-04-23
Applicant: DR. REDDYS LABORATORIES LIMITED
Inventor： PEDDY, Vishweshwar , CHENNURU, Ramanaiah , RAMAKRISHNAN, Srividya
CPC classification number: C07D401/14
Abstract: Crystalline Forms R5, R5a, R5b and R6 of nilotinib hydrochloride and processes for their preparation.
Abstract translation: 盐酸尼洛替尼的结晶形式R5，R5a，R5b和R6及其制备方法。
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公开(公告)号：WO2014115082A1
公开(公告)日：2014-07-31
申请号：PCT/IB2014/058456
申请日：2014-01-22
Applicant: DR. REDDYS LABORATORIES LIMITED
Inventor： BONDU, Vinod Kumar Reddy , BABLA, Irfan , KANNUSAMY, Saravanan , SESHADRI, Raja Kumar , VURE, Prasad
IPC: A61K9/20 , A61K9/48 , A61K31/506
CPC classification number: A61K31/506 , A61K9/2027 , A61K9/2059 , A61K9/2077 , A61K9/2095
Abstract: Aspects of the present invention relate to pharmaceutical formulations comprising imatinib or its salts, isomers, racemates, enantiomers, hydrates, solvates, metabolites, and polymorphs, and mixtures thereof. Further aspects relate to processes for preparing pharmaceutical formulations comprising imatinib or its salts, together with at least one pharmaceutically acceptable excipient.
Abstract translation: 本发明的方面涉及包含伊马替尼或其盐，异构体，外消旋物，对映异构体，水合物，溶剂化物，代谢物和多晶型物的药物制剂及其混合物。 其它方面涉及用于制备包含伊马替尼或其盐以及至少一种药学上可接受的赋形剂的药物制剂的方法。
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Patent Agency Ranking
公开(公告)号：WO2013024495A1
公开(公告)日：2013-02-21
申请号：PCT/IN2012/000558
申请日：2012-08-17
Applicant: DR. REDDYS LABORATORIES LIMITED , KOCHERLAKOTA, Chandrasekhar , BANDA, Nagaraju , SINGH, Tarun , VURE, Prasad , BISWAS, Moumita , BHAGWATWAR, Harshal Prabhakar , VAYA, Navin , KHATI, Nirmal , AHMED, Shaik Riyaz
Inventor： KOCHERLAKOTA, Chandrasekhar , BANDA, Nagaraju , SINGH, Tarun , VURE, Prasad , BISWAS, Moumita , BHAGWATWAR, Harshal Prabhakar , VAYA, Navin , KHATI, Nirmal , AHMED, Shaik Riyaz
CPC classification number: A61K9/0019 , A61K9/19 , A61K31/337 , A61K47/10 , A61K47/12 , A61K47/26
Abstract: Aspects of the present application relate to pharmaceutical formulations comprising cabazitaxel or its pharmaceutically acceptable salts, isomers, racemates, enantiomers, hydrates, solvates, metabolites, polymorphs, and mixtures thereof. In embodiments, formulations are in the form of ready-to-use solutions or concentrates, or lyophilized forms. Further aspects relate to stable injectable compositions of cabazitaxel ready for direct dilution with infusion solution, without any need for preparation of premix solutions, and manufacturing processes thereof.
Abstract translation: 本申请的方面涉及包含卡巴他赛或其药学上可接受的盐，异构体，外消旋体，对映体，水合物，溶剂合物，代谢物，多晶型物及其混合物的药物制剂。 在实施方案中，制剂是即用型溶液或浓缩物或冻干形式的形式。 另外的方面涉及准备用输注溶液直接稀释的卡马西他汀的稳定的可注射组合物，而不需要制备预混物溶液及其制备方法。
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公开(公告)号：WO2013008253A3
公开(公告)日：2013-01-17
申请号：PCT/IN2012/000488
申请日：2012-07-11
Applicant: DR. REDDYS LABORATORIES LIMITED , KONATHAM, Suresh , MALLADI, Madhusudan , VURE, Prasad , BISWAS, Moumita , BHISE, Rahul , KOTA, Ramesh
Inventor： KONATHAM, Suresh , MALLADI, Madhusudan , VURE, Prasad , BISWAS, Moumita , BHISE, Rahul , KOTA, Ramesh
IPC: A61K9/00 , A61K31/506 , A61K9/14 , A61K9/48
Abstract: Aspects of the present application relate to pharmaceutical formulations comprising imatinib or its salts, isomers, racemates, enantiomers, hydrates, solvates, metabolites, and polymorphs, and mixtures thereof. Further aspects relate to processes for preparing pharmaceutical formulations comprising imatinib or its salts, together with at least one pharmaceutically acceptable excipient.
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公开(公告)号：WO2017149450A3
公开(公告)日：2017-09-08
申请号：PCT/IB2017/051164
申请日：2017-02-28
Applicant: DR. REDDYS LABORATORIES
Inventor： SHARMA, Ketan , DHUNDI, Ritesh M , SRIVASTAVA, Shitanshu
Abstract: The present invention relates to the field of preparative chromatography. The invention provides a rapid method to assess the chromatographic column lifetime during a preparative scale chromatography. The method specifically measures the difference in the column back pressures obtained at two different flow rates, during the cleaning step of a chromatographic process, to assess the re-usability or lifetime of the resin/matrix.
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8.发明申请FIXED DOSE PHARMACEUTICAL FORMULATIONS OF ANALGESIC AND ANTI-SPASMODIC DRUGS 审中-公开固定剂和抗肿瘤药物的固定配方药物制剂
公开(公告)号：WO2016075617A1
公开(公告)日：2016-05-19
申请号：PCT/IB2015/058667
申请日：2015-11-10
Applicant: DR. REDDYS LABORATORIES LIMITED
Inventor： KRISHNAKANT, Tulsiram Gandhi , KEESARA, Venkateshwar Reddy , SEETHARAMAN, Sritharan , DESHPANDE, Pandurang , VERMA, Himanshu
IPC: A61K31/216 , A61P1/06 , A61P29/00 , A61P25/04
CPC classification number: A61K31/47 , A61K9/2059 , A61K9/2077 , A61K9/209 , A61K31/192 , A61K2300/00
Abstract: The invention relates to a fixed dose pharmaceutical formulation comprising analgesic agent and anti-spasmodic agent and one or more pharmaceutically acceptable excipients wherein the pharmaceutical formulation is used for relief of menstrual and abdominal cramps associated with dysmenorrhea.
Abstract translation: 本发明涉及包含止痛剂和抗痉挛剂以及一种或多种药学上可接受的赋形剂的固定剂量药物制剂，其中药物制剂用于缓解与痛经相关的月经和腹部痉挛。
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公开(公告)号：WO2013175395A2
公开(公告)日：2013-11-28
申请号：PCT/IB2013/054167
申请日：2013-05-21
Applicant: DR. REDDYS LABORATORIES LIMITED
Inventor： VARANASI, Ganesh , MACHARLA, Prabhakar , VEMPATI, Chandrasekhar , BANDICHHOR, Rakeshwar , DAHANUKAR, Vilas Hareshwar , IQBAL, Javed , ORUGANTI, Srinivas , RAPOLU, Rajesh Kumar , NARIYAM, Munaswamy Sekhar , NETI, Srinivasan
CPC classification number: C07D209/52
Abstract: The present application relate to improved processes for preparing saxagliptin or its salt and intermediates thereof.
Abstract translation: 本申请涉及制备沙格列汀或其盐及其中间体的改进方法。
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