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公开(公告)号：WO2017149450A2
公开(公告)日：2017-09-08
申请号：PCT/IB2017/051164
申请日：2017-02-28
Applicant: DR. REDDYS LABORATORIES
Inventor： SHARMA, Ketan , DHUNDI, Ritesh M , SRIVASTAVA, Shitanshu
IPC: B01D15/08
CPC classification number: B01D15/08 , B01D15/163 , G01N30/32 , G01N30/86 , G01N30/88 , G01N2030/889
Abstract: The present invention relates to the field of preparative chromatography. The invention provides a rapid method to assess the chromatographic column lifetime during a preparative scale chromatography. The method specifically measures the difference in the column back pressures obtained at two different flow rates, during the cleaning step of a chromatographic process, to assess the re-usability or lifetime of the resin/matrix.
Abstract translation: 本发明涉及制备色谱领域。 本发明提供了一种评估制备级色谱过程中色谱柱寿命的快速方法。 该方法具体测量在色谱过程的清洁步骤期间在两种不同流速下获得的柱背压差，以评估树脂/基质的可再使用性或寿命。
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公开(公告)号：WO2017149450A3
公开(公告)日：2017-09-08
申请号：PCT/IB2017/051164
申请日：2017-02-28
Applicant: DR. REDDYS LABORATORIES
Inventor： SHARMA, Ketan , DHUNDI, Ritesh M , SRIVASTAVA, Shitanshu
Abstract: The present invention relates to the field of preparative chromatography. The invention provides a rapid method to assess the chromatographic column lifetime during a preparative scale chromatography. The method specifically measures the difference in the column back pressures obtained at two different flow rates, during the cleaning step of a chromatographic process, to assess the re-usability or lifetime of the resin/matrix.
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