公开(公告)号：WO1998034114A1

公开(公告)日：1998-08-06

申请号：PCT/EP1997000403

申请日：1997-01-30

Applicant: MERCK PATENT GMBH ,  DREMEL, Bernd

Inventor： MERCK PATENT GMBH

IPC: G01N33/543

CPC classification number: G01N33/54386 ,  G01N33/54333 ,  Y10S435/97 ,  Y10S435/971 ,  Y10S436/805 ,  Y10S436/806

Abstract: The invention concerns a method for the immunological determination of an analyte in a sample using magnetic particles coated with the analyte to be determined or analyte-specific bonding partners and directly detectable non-magnetic particles coated with analyte-specific bonding partners or the analyte to be determined or using a non-magnetic substance which is indirectly detectable, and incubation of the reaction mixture. The method is characterized in that the magnetic particles are subsequently separated from the reaction mixture using a magnetic test strip and the analyte concentration is determined directly.

Abstract translation: 本发明涉及一种用于免疫学测定的样品中的分析物的方法，通过向被确定涂覆的分析物的装置或分析物特异性结合伙伴磁性颗粒和分析物特异性的结合伴侣或涂覆的分析物由可证明的确定直接可检测的非磁性颗粒或非间接 -magentischen物质，将反应混合物温育。 该方法的特征在于所述磁性颗粒然后使用磁力测试条从反应混合物中分离和分析物的浓度直接确定。

公开(公告)号：WO1992005450A1

公开(公告)日：1992-04-02

申请号：PCT/EP1991001767

申请日：1991-09-17

Applicant: GESELLSCHAFT FÜR BIOTECHNOLOGISCHE FORSCHUNG MBH ... ,  HANISCH, Detlef ,  SCHILLIG, Henning ,  DREMEL, Bernd

Inventor： GESELLSCHAFT FÜR BIOTECHNOLOGISCHE FORSCHUNG MBH ...

IPC: G01N35/08

CPC classification number: G01N1/38 ,  B01F15/00928 ,  G01N30/04 ,  G01N35/085 ,  G01N2035/00514

Abstract: A process and a device for implementing the process allow dilutions to be produced in a multiple agitator and mixer module that can be used as a specimen preparation unit in analytical appliances, such as for analysis by injection in a fluid stream. The multiple agitator and mixer module essentially comprises a plurality of agitator and mixer chambers the volume of which can be variably and individually set according to the needs of the analysis to be carried out, so that it is highly adaptable to various analytical appliances. Further advantageous developments of the invention are also disclosed.

Abstract translation: 用于实施该方法的方法和装置允许在可用作分析仪器中的样品制备单元的多重搅拌器和混合器模块中产生稀释，例如用于通过在流体流中注射进行分析。 多重搅拌器和混合器模块基本上包括多个搅拌器和混合器室，其容积可以根据要执行的分析的需要而可变地和单独地设定，使得其高度适用于各种分析设备。 还公开了本发明的进一步有利的发展。