公开(公告)号：WO2010139451A3

公开(公告)日：2011-05-26

申请号：PCT/EP2010003308

申请日：2010-06-01

Applicant: AAP BIOMATERIALS GMBH ,  DINGELDEIN ELVIRA ,  GASQUERES CYRILLE ,  WITTE FRANK ,  ELIZIER AMIR

Inventor： DINGELDEIN ELVIRA ,  GASQUERES CYRILLE ,  WITTE FRANK ,  ELIZIER AMIR

IPC: A61L27/30 ,  A61L27/54 ,  C23C18/00 ,  C25D11/02

CPC classification number: C25D11/024 ,  A61L27/306 ,  A61L27/54 ,  A61L31/088 ,  A61L31/16 ,  A61L2300/102 ,  A61L2300/104 ,  A61L2300/606 ,  A61L2300/802 ,  A61L2400/12 ,  A61L2400/18 ,  A61L2420/06 ,  C25D11/005 ,  C25D11/022

Abstract: The present invention relates generally to an antibacterial coating which is composed of silver, to medical tools and to implants comprising such a coating and to a method as well to an apparatus for the production of such a coating. The medical tools or the dental or orthopaedic implant comprises a metal or metal alloy having a treated surface wherein the treated surface is at least partially converted to an oxide film by plasma electrolytic oxidation using a colloid-dispersed system and wherein the converted surface is partially covered by islands formed by colloid-dispersed silver-particles of the colloid-dispersed system. An Ag-TiO2 coating according to the invention shows excellent properties in terms of antibacterial efficacy (even against multi-resistant strains), adhesion and biocompatibility. The life-time of an implant in a human body is increased. The antibacterial coating can be used in the field of traumatology, orthopaedic, osteosynthesis and/or endoprothesis, especially where high infection risk exists. A high number of currently existing medical tools and implants can benefit from such a coating.

Abstract translation: 本发明一般涉及一种由银组成的抗菌涂层，医用工具以及包含这种涂层的植入物以及制备这种涂层的方法。 医疗工具或牙科或矫形植入物包括具有处理表面的金属或金属合金，其中经处理的表面至少部分地通过使用胶体分散系统的等离子体电解氧化转化为氧化膜，并且其中转换的表面被部分覆盖 由胶体分散体系的胶体分散的银颗粒形成的岛。 根据本发明的Ag-TiO 2涂层在抗菌功效（甚至针对多抗性菌株），粘附和生物相容性方面表现出优异的性质。 植入物在人体内的寿命增加。 抗菌涂层可用于创伤学，骨科，骨接合术和/或内切除术领域，特别是在存在高感染风险的地方。 目前存在的大量医疗工具和植入物可以受益于这种涂层。

公开(公告)号：WO2010139451A2

公开(公告)日：2010-12-09

申请号：PCT/EP2010/003308

申请日：2010-06-01

Applicant: AAP BIOMATERIALS GMBH ,  DINGELDEIN, Elvira ,  GASQUERES, Cyrille ,  WITTE, Frank ,  ELIZIER, Amir

Inventor： DINGELDEIN, Elvira ,  GASQUERES, Cyrille ,  WITTE, Frank ,  ELIZIER, Amir

CPC classification number: C25D11/024 ,  A61L27/306 ,  A61L27/54 ,  A61L31/088 ,  A61L31/16 ,  A61L2300/102 ,  A61L2300/104 ,  A61L2300/606 ,  A61L2300/802 ,  A61L2400/12 ,  A61L2400/18 ,  A61L2420/06 ,  C25D11/005 ,  C25D11/022

Abstract: The present invention relates generally to an antibacterial coating which is composed of silver, to medical tools and to implants comprising such a coating and to a method as well to an apparatus for the production of such a coating. The medical tools or the dental or orthopaedic implant comprises a metal or metal alloy having a treated surface wherein the treated surface is at least partially converted to an oxide film by plasma electrolytic oxidation using a colloid-dispersed system and wherein the converted surface is partially covered by islands formed by colloid-dispersed silver-particles of the colloid-dispersed system. An Ag-TiO 2 coating according to the invention shows excellent properties in terms of antibacterial efficacy (even against multi-resistant strains), adhesion and biocompatibility. The life-time of an implant in a human body is increased. The antibacterial coating can be used in the field of traumatology, orthopaedic, osteosynthesis and/or endoprothesis, especially where high infection risk exists. A high number of currently existing medical tools and implants can benefit from such a coating.

Abstract translation: 本发明一般涉及一种由银组成的抗菌涂层，医用工具以及包含这种涂层的植入物以及制备这种涂层的方法。 医疗工具或牙科或矫形植入物包括具有处理表面的金属或金属合金，其中经处理的表面至少部分地通过使用胶体分散系统的等离子体电解氧化转化为氧化膜，并且其中转换的表面被部分覆盖 由胶体分散体系的胶体分散的银颗粒形成的岛。 根据本发明的Ag-TiO 2涂层在抗菌功效（甚至针对多抗性菌株），粘附和生物相容性方面表现出优异的性质。 植入物在人体内的寿命增加。 抗菌涂层可用于创伤学，骨科，骨接合术和/或内切除术领域，特别是在存在高感染风险的地方。 目前存在的大量医疗工具和植入物可以受益于这种涂层。