METHOD OF PROVIDING MULTIPLE SEPARATION MODES IN A FEEDER
    2.
    发明申请
    METHOD OF PROVIDING MULTIPLE SEPARATION MODES IN A FEEDER 审中-公开
    在饲料中提供多个分离模式的方法

    公开(公告)号:WO2007127404A2

    公开(公告)日:2007-11-08

    申请号:PCT/US2007010301

    申请日:2007-04-26

    Abstract: Discrete means of setting a feeder to process a wide range of media, i.e., sheets, slips, envelopes, booklets and hand collated documents, etc. as well as providing a method of utilizing the feeder for manual feed operation. The foregoing is accomplished by a friction-clutch retard feeder equipped with one or more friction clutches. When a selection lever is moved to a position 1, a primary clutch engages the separator roller with a resistive torque T 1 . The selection lever configures the mechanism such that the separator roller rotation is resisted entirely by the torque of the primary clutch. When the selection lever is moved to a position 2, the ground of the primary clutch is removed, and the rotation of the separator roll is coupled through a gear ratio to a secondary clutch. The selection of the gear ratio and the - value of the secondary clutch allows the separation mechanism to be resisted by a second torque, T 2 , which can be lower than T 1 .

    Abstract translation: 分离装置,用于设置进料器以处理各种介质,即纸张,单据,信封,小册子和手工整理的文件等,以及提供一种利用进料器进行手动进料操作的方法。 前述是通过装备有一个或多个摩擦离合器的摩擦离合器延迟给料器实现的。 当选择杆移动到位置1时,主离合器以阻力矩T 1接合分离辊。 选择杆配置机构,使得分离器辊的旋转完全由主离合器的扭矩抵抗。 当选择杆移动到位置2时,主离合器的地面被移除,并且分离器辊的旋转通过齿轮比耦合到二次离合器。 齿轮比的选择和二次离合器的值允许分离机构抵抗可以低于T 1的第二扭矩T 2 2 < 。

    METHOD OF PROVIDING MULTIPLE SEPARATION MODES IN A FEEDER

    公开(公告)号:WO2007127404A3

    公开(公告)日:2007-11-08

    申请号:PCT/US2007/010301

    申请日:2007-04-26

    Abstract: Discrete means of setting a feeder to process a wide range of media, i.e., sheets, slips, envelopes, booklets and hand collated documents, etc. as well as providing a method of utilizing the feeder for manual feed operation. The foregoing is accomplished by a friction-clutch retard feeder equipped with one or more friction clutches. When a selection lever is moved to a position 1, a primary clutch engages the separator roller with a resistive torque T 1 . The selection lever configures the mechanism such that the separator roller rotation is resisted entirely by the torque of the primary clutch. When the selection lever is moved to a position 2, the ground of the primary clutch is removed, and the rotation of the separator roll is coupled through a gear ratio to a secondary clutch. The selection of the gear ratio and the - value of the secondary clutch allows the separation mechanism to be resisted by a second torque, T 2 , which can be lower than T 1 .

    PRINTING OR DISPENSING A SUSPENSION SUCH AS THREE-DIMENSIONAL PRINTING OF DOSAGE FORMS
    10.
    发明申请
    PRINTING OR DISPENSING A SUSPENSION SUCH AS THREE-DIMENSIONAL PRINTING OF DOSAGE FORMS 审中-公开
    打印或分配暂停作为剂量形式的三维打印

    公开(公告)号:WO03041690A2

    公开(公告)日:2003-05-22

    申请号:PCT/US0143722

    申请日:2001-11-21

    Abstract: The invention includes dispensing a suspension containing solid particles for use in manufacturing a dosage form or other biomedical article by 3DP. The suspension contains solid particles suspended in a liquid. The solid particles may be one or more Active Pharmaceutical Ingredients. The solid particles may be particles of material that are insoluble in the liquid, or they may be particles of a substance that have already dissolved in the liquid up to the saturation level and are present in a concentration beyond what can be dissolved. In addition to solid particles, the liquid may also contain other substances dissolved in it, either substances containing Active Pharmaceutical Ingredients (API) or substances without API. One aspect of the invention includes prevention of agglomeration by adding one or more of several categories of additives to the suspending liquid. Another aspect of the invention includes manipulating the surface charge of the particles in an API suspension to prevent particles from agglomerating. A further aspect of the invention includes an amorphous API that has a greater bioavailability than the corresponding crystalline material. Yet another aspect of the present invention includes a system for providing continuous circulation of the suspension such that the solid particles remain dispersed in the suspension.

    Abstract translation: 本发明包括分配含有固体颗粒的悬浮液,用于通过3DP制造剂型或其它生物医学制品。 悬浮液含有悬浮在液体中的固体颗粒。 固体颗粒可以是一种或多种活性药物成分。 固体颗粒可以是不溶于液体的材料颗粒,或者它们可以是已经溶解在液体中的物质的颗粒直到饱和水平并且以超过可溶解的浓度存在。 除了固体颗粒外,液体还可能含有溶解在其中的其他物质,含有活性药物成分(API)的物质或不含API的物质。 本发明的一个方面包括通过向悬浮液中加入几种类型的添加剂中的一种或多种来防止附聚。 本发明的另一方面包括操作API悬浮液中颗粒的表面电荷以防止颗粒附聚。 本发明的另一方面包括具有比相应的结晶材料更大的生物利用度的无定形API。 本发明的另一方面包括一种用于提供悬浮液的连续循环使得固体颗粒保持分散在悬浮液中的系统。

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