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1.HLA-A2 TUMOR ASSOCIATED ANTIGEN PEPTIDES AND COMPOSITIONS 审中-公开
Title translation: HLA-A2肿瘤相关抗原肽和组合物公开(公告)号:WO2004094454A3
公开(公告)日:2006-11-09
申请号:PCT/US2004011895
申请日:2004-04-16
Applicant: IDM PHARMA INC , FIKES JOHN D , ISHIOKA GLENN , SETTE ALESSANDRO , CHESNUT ROBERT W
Inventor: FIKES JOHN D , ISHIOKA GLENN , SETTE ALESSANDRO , CHESNUT ROBERT W
IPC: C07K5/00 , A61K38/00 , C07K20060101
CPC classification number: A61K39/0011 , A61K39/39 , A61K2039/55511 , A61K2039/55566 , A61K2039/57 , A61K2039/572 , A61K2039/70 , C07K7/06 , C07K14/47
Abstract: A peptide or composition comprising at least one HLA-A2 epitope or analog from CEA, HER2/neu, MAGE2, MAGE3, or p53.
Abstract translation: 包含至少一种HLA-A2表位或CEA,HER2 / neu,MAGE2,MAGE3或p53的类似物的肽或组合物。
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2.HLA-A2 TUMOR ASSOCIATED ANTIGEN PEPTIDES AND COMPOSITIONS 审中-公开
Title translation: HLA-A2肿瘤相关抗原肽和组合物公开(公告)号:WO2004094454A2
公开(公告)日:2004-11-04
申请号:PCT/US2004/011895
申请日:2004-04-16
Applicant: EPIMMUNE, INC. , FIKES, John, D. , ISHIOKA, Glenn , SETTE, Alessandro , CHESTNUT, Robert, W.
Inventor: FIKES, John, D. , ISHIOKA, Glenn , SETTE, Alessandro , CHESTNUT, Robert, W.
IPC: C07K
CPC classification number: A61K39/0011 , A61K39/39 , A61K2039/55511 , A61K2039/55566 , A61K2039/57 , A61K2039/572 , A61K2039/70 , C07K7/06 , C07K14/47
Abstract: A peptide or composition comprising at least one HLA-A2 epitope or analog from CEA, HER2/neu, MAGE2, MAGE3, or p53.
Abstract translation: 包含至少一种HLA-A2表位或CEA,HER2 / neu,MAGE2,MAGE3或p53的类似物的肽或组合物。
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3.HLA-A1, A2 -A3,-A24,-B7,AND -B44 TUMOR ASSOCIATED ANTIGEN PEPTIDES AND COMPOSITIONS 审中-公开
Title translation: HLA-A1,A2 -A3,-A24,-B7和-B44肿瘤相关抗原肽和组合物公开(公告)号:WO2004052917A2
公开(公告)日:2004-06-24
申请号:PCT/US2003/038949
申请日:2003-12-10
Applicant: EPIMMUNE INC. , KEOGH, Elissa, A. , SOUTHWOOD, Scott , FIKES, John, D. , SETTE, Alessandro
Inventor: KEOGH, Elissa, A. , SOUTHWOOD, Scott , FIKES, John, D. , SETTE, Alessandro
IPC: C07K
CPC classification number: C07K14/4746 , A61K38/00 , C07K14/4748 , C07K14/70503 , C07K14/71
Abstract: A peptide or composition comprising at least one epitope or analog from CEA, HER2/neu, MAGE2, MAGE3, or p53.
Abstract translation: 包含至少一种来自CEA,HER2 / neu,MAGE2,MAGE3或p53的表位或类似物的肽或组合物。
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4.
公开(公告)号:WO1995004542A1
公开(公告)日:1995-02-16
申请号:PCT/US1994008721
申请日:1994-08-02
Applicant: CYTEL CORPORATION , FIKES, John, D. , LIVINGSTON, Brian, D. , SETTE, Alessandro, D. , SIDNEY, John, C.
Inventor: CYTEL CORPORATION
IPC: A61K38/00
CPC classification number: C07K14/4748 , A61K38/00 , A61K39/00
Abstract: The complete nucleotide and amino acid sequences of the human MAGE-1 antigen are provided. Peptides from residues of the C-terminal are used to define epitopes that stimulate HLA-restricted cytotoxic T lymphocyte activity against MAGE-1 antigens. The peptides are particularly useful in methods for stimulating the immune response of individuals against MAGE-1 antigens associated with melanomas.
Abstract translation: 提供了人MAGE-1抗原的完整核苷酸和氨基酸序列。 来自C末端残基的肽用于定义刺激针对MAGE-1抗原的HLA限制性细胞毒性T淋巴细胞活性的表位。 这些肽特别可用于刺激个体对与黑素瘤相关的MAGE-1抗原的免疫应答的方法。
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公开(公告)号:WO2009059011A2
公开(公告)日:2009-05-07
申请号:PCT/US2008081799
申请日:2008-10-30
Applicant: MAYO FOUNDATION , DISIS MARY L , FIKES JOHN D , BEEBE MELANIE , ISHIOKA GLENN , KNUTSON KEITH L
Inventor: DISIS MARY L , FIKES JOHN D , BEEBE MELANIE , ISHIOKA GLENN , KNUTSON KEITH L
IPC: C07K14/435 , A61K38/00 , C07K7/00 , C07K14/00 , C07K14/72
CPC classification number: C07K14/71 , A61K38/00 , A61K2039/572 , C07K7/08 , C07K14/4738 , C07K14/4743 , C07K14/4748 , C07K14/70503
Abstract: The present invention provides HLA-DR (MHC class II) binding peptides derived from the ovarian/breast cancer associated antigens, Human Epidermal Growth Factor Receptor 2 (HER-2/neu), Carcinoembryonic Antigen (CEA), Insulin Growth Factor Binding Protein 2 (IGFBP-2), and Cyclin D1. The immunogenic peptides can be used in cancer vaccines.
Abstract translation: 本发明提供了衍生自卵巢/乳腺癌相关抗原的人类表皮生长因子受体2(HER-2 / neu),癌胚抗原(CEA),胰岛素生长因子结合蛋白2(HLA-DR(MHC II类) (IGFBP-2)和细胞周期蛋白D1。 免疫原性肽可用于癌症疫苗。
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6.HLA-A2 TUMOR ASSOCIATED ANTIGEN PEPTIDES AND COMPOSITIONS 审中-公开
Title translation: HLA-A2肿瘤相关抗原肽和组合物公开(公告)号:WO2004094454A8
公开(公告)日:2005-07-21
申请号:PCT/US2004011895
申请日:2004-04-16
Applicant: EPIMMUNE INC , FIKES JOHN D , ISHIOKA GLENN , SETTE ALESSANDRO , CHESNUT ROBERT W
Inventor: FIKES JOHN D , ISHIOKA GLENN , SETTE ALESSANDRO , CHESNUT ROBERT W
IPC: A61K38/00 , C07K20060101 , C07K
CPC classification number: A61K39/0011 , A61K39/39 , A61K2039/55511 , A61K2039/55566 , A61K2039/57 , A61K2039/572 , A61K2039/70 , C07K7/06 , C07K14/47
Abstract: A peptide or composition comprising at least one HLA-A2 epitope or analog from CEA, HER2/neu, MAGE2, MAGE3, or p53.
Abstract translation: 包含至少一种HLA-A2表位或CEA,HER2 / neu,MAGE2,MAGE3或p53的类似物的肽或组合物。
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7.HLA-A1, A2 -A3,-A24,-B7,AND -B44 TUMOR ASSOCIATED ANTIGEN PEPTIDES AND COMPOSITIONS 审中-公开
Title translation: HLA-A1,A2-A3,-A24,-B7和-B44肿瘤相关的抗原肽和组合物公开(公告)号:WO2004052917A9
公开(公告)日:2004-09-30
申请号:PCT/US0338949
申请日:2003-12-10
Applicant: EPIMMUNE INC , KEOGH ELISSA A , SOUTHWOOD SCOTT , FIKES JOHN D , SETTE ALESSANDRO
Inventor: KEOGH ELISSA A , SOUTHWOOD SCOTT , FIKES JOHN D , SETTE ALESSANDRO
IPC: A61K38/00 , C07K14/47 , C07K14/705 , C07K14/71 , C07K
CPC classification number: C07K14/4746 , A61K38/00 , C07K14/4748 , C07K14/70503 , C07K14/71
Abstract: A peptide or composition comprising at least one epitope or analog from CEA, HER2/neu, MAGE2, MAGE3, or p53.
Abstract translation: 包含至少一种来自CEA,HER2 / neu,MAGE2,MAGE3或p53的表位或类似物的肽或组合物。
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公开(公告)号:WO2009059011A3
公开(公告)日:2009-11-05
申请号:PCT/US2008081799
申请日:2008-10-30
Applicant: MAYO FOUNDATION , UNIV WASHINGTON , KNUTSON KEITH L , DISIS MARY L , FIKES JOHN D , BEEBE MELANIE , ISHIOKA GLENN
Inventor: KNUTSON KEITH L , DISIS MARY L , FIKES JOHN D , BEEBE MELANIE , ISHIOKA GLENN
IPC: C07K14/435 , A61K38/00 , C07K7/00 , C07K14/00 , C07K14/725
CPC classification number: C07K14/71 , A61K38/00 , A61K2039/572 , C07K7/08 , C07K14/4738 , C07K14/4743 , C07K14/4748 , C07K14/70503
Abstract: The present invention provides HLA-DR (MHC class II) binding peptides derived from the ovarian/breast cancer associated antigens, Human Epidermal Growth Factor Receptor 2 (HER-2/neu), Carcinoembryonic Antigen (CEA), Insulin Growth Factor Binding Protein 2 (IGFBP-2), and Cyclin D1. The immunogenic peptides can be used in cancer vaccines.
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公开(公告)号:WO2009059011A9
公开(公告)日:2009-05-07
申请号:PCT/US2008/081799
申请日:2008-10-30
Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH , UNIVERSITY OF WASHINGTON , KNUTSON, Keith L. , DISIS, Mary, L. , FIKES, John, D. , BEEBE, Melanie , ISHIOKA, Glenn
Inventor: KNUTSON, Keith L. , DISIS, Mary, L. , FIKES, John, D. , BEEBE, Melanie , ISHIOKA, Glenn
IPC: C07K14/435 , C07K14/725 , C07K14/00 , C07K7/00 , A61K38/00
Abstract: The present invention provides HLA-DR (MHC class II) binding peptides derived from the ovarian/breast cancer associated antigens, Human Epidermal Growth Factor Receptor 2 (HER-2/neu), Carcinoembryonic Antigen (CEA), Insulin Growth Factor Binding Protein 2 (IGFBP-2), and Cyclin D1. The immunogenic peptides can be used in cancer vaccines.
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10.HLA-A1, A2 -A3,-A24,-B7,AND -B44 TUMOR ASSOCIATED ANTIGEN PEPTIDES AND COMPOSITIONS 审中-公开
Title translation: HLA-A1,A2 -A3,-A24,-B7和-B44肿瘤相关抗原肽和组合物公开(公告)号:WO2004052917A3
公开(公告)日:2005-06-23
申请号:PCT/US0338949
申请日:2003-12-10
Applicant: EPIMMUNE INC , KEOGH ELISSA A , SOUTHWOOD SCOTT , FIKES JOHN D , SETTE ALESSANDRO
Inventor: KEOGH ELISSA A , SOUTHWOOD SCOTT , FIKES JOHN D , SETTE ALESSANDRO
IPC: A61K38/00 , C07K14/47 , C07K14/705 , C07K14/71
CPC classification number: C07K14/4746 , A61K38/00 , C07K14/4748 , C07K14/70503 , C07K14/71
Abstract: A peptide or composition comprising at least one epitope or analog from CEA, HER2/neu, MAGE2, MAGE3, or p53.
Abstract translation: 包含至少一种来自CEA,HER2 / neu,MAGE2,MAGE3或p53的表位或类似物的肽或组合物。
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