公开(公告)号：WO1997037602A2

公开(公告)日：1997-10-16

申请号：PCT/US1997005560

申请日：1997-04-04

Applicant: CYNOSURE, INC. ,  FURUMOTO, Horace, W. ,  CHO, George ,  McDANIEL, David, H. ,  KOSCHMANN, Eric ,  RIZZO, Antonio, G.

Inventor： CYNOSURE, INC.

IPC: A61B17/41

CPC classification number: H01S3/092 ,  A61B18/203 ,  A61B2017/00172 ,  A61B2017/22085 ,  A61B2018/00452 ,  A61B2018/00476 ,  H01S3/08072 ,  H01S3/1633 ,  H01S2301/08

Abstract: A long pulse alexandrite laser for treating dermatological specimens is disclosed. The use of alexandrite allows operation in the near-infrared, specifically in a 50 nm range surrounding 755. Infrared in this range allows good penetration while still achieving an acceptable ratio of hemoglobin to melanin absorption. In operation, the laser generates pulses having a durations between 5 and 100 msec and fluences between 10 and 50 J/cm . A light delivery system is provided that transmits the laser light output pulse to dermatological targets of a patient. The invention is also directed to a hair removal system. Here, it is desirable to use an index-matching application on the skin sections to be treated, and a visual indicator is thermo- or photo-responsive or otherwise responsive to the laser light pulse to generate a visible change. This provides the operator with a record of those parts of the skin that have already been treated. Finally, the invention is directed to a combined sclerotherapy and light treatment method and kit for unwanted veins. Substantially increased success, in the range of 90-100 % has been achieved by implementing a dwell time of between 12 hours and 6 months between the light-based therapy and the sclerotherapy. Preferably, the light-based therapy is performed before the sclerotherapy. Success can be achieved by performing the sclerotherapy followed by the light-based therapy after the dwell time, however.

Abstract translation: 公开了用于治疗皮肤病学标本的长脉冲亚历山大激光。 使用alexandrite可以在近红外线中进行操作，特别是在围绕755的50nm范围内。在该范围内的红外线允许良好的穿透，同时仍然达到可接受的血红蛋白与黑色素吸收比。 在操作中，激光产生持续时间在5和100毫秒之间的脉冲，并且在10和50J / cm 2之间的通量。 提供了一种光输送系统，其将激光输出脉冲发送到患者的皮肤病学靶标。 本发明还涉及一种脱毛系统。 这里，期望在要处理的皮肤部分上使用折射率匹配应用，并且视觉指示器是热敏或光敏响应的或以其他方式响应于激光脉冲以产生可见变化。 这为操作者提供已经被处理的皮肤部分的记录。 最后，本发明涉及用于不需要的静脉的组合的硬化疗法和光治疗方法和试剂盒。 通过在光疗法和硬化疗法之间实施12个月至6个月之间的停留时间，在90-100％的范围内大大提高了成功率。 优选地，光硬化治疗在硬化治疗之前进行。 然而，通过在停留时间之后进行硬化治疗，然后进行基于光的治疗，可以实现成功。

公开(公告)号：WO9737602A3

公开(公告)日：1997-12-24

申请号：PCT/US9705560

申请日：1997-04-04

Applicant: CYNOSURE INC ,  FURUMOTO HORACE W ,  CHO GEORGE ,  MCDANIEL DAVID H ,  KOSCHMANN ERIC ,  RIZZO ANTONIO G

Inventor： FURUMOTO HORACE W ,  CHO GEORGE ,  MCDANIEL DAVID H ,  KOSCHMANN ERIC ,  RIZZO ANTONIO G

IPC: A61B17/00 ,  A61B17/22 ,  A61B18/20 ,  A61N5/06 ,  H01S3/08 ,  H01S3/092 ,  H01S3/16 ,  A61B17/41

CPC classification number: H01S3/092 ,  A61B18/203 ,  A61B2017/00172 ,  A61B2017/22085 ,  A61B2018/00452 ,  A61B2018/00476 ,  H01S3/08072 ,  H01S3/1633 ,  H01S2301/08

Abstract: A long pulse alexandrite laser for treating dermatological specimens is disclosed. The use of alexandrite allows operation in the near-infrared, specifically in a 50 nm range surrounding 755. Infrared in this range allows good penetration while still achieving an acceptable ratio of hemoglobin to melanin absorption. In operation, the laser generates pulses having a durations between 5 and 100 msec and fluences between 10 and 50 J/cm2. A light delivery system is provided that transmits the laser light output pulse to dermatological targets of a patient. The invention is also directed to a hair removal system. Here, it is desirable to use an index-matching application on the skin sections to be treated, and a visual indicator is thermo- or photo-responsive or otherwise responsive to the laser light pulse to generate a visible change. This provides the operator with a record of those parts of the skin that have already been treated. Finally, the invention is directed to a combined sclerotherapy and light treatment method and kit for unwanted veins. Substantially increased success, in the range of 90-100 % has been achieved by implementing a dwell time of between 12 hours and 6 months between the light-based therapy and the sclerotherapy. Preferably, the light-based therapy is performed before the sclerotherapy. Success can be achieved by performing the sclerotherapy followed by the light-based therapy after the dwell time, however.