公开(公告)号：WO0024266A3

公开(公告)日：2000-07-13

申请号：PCT/US9922657

申请日：1999-09-29

Applicant: GALAGEN INC

Inventor： BOSTWICK EILEEN F

IPC: A23C9/13 ,  A23C11/06 ,  A23C11/10 ,  A23L1/30 ,  A23J3/08 ,  A23J3/16 ,  A23L1/305

CPC classification number: A23C9/1307 ,  A23C11/06 ,  A23C11/103 ,  A23C11/106

Abstract: The present invention is directed to compositions including a soy product and an active immunoglobulin for nutrition and overall health benefits to humans and animals. The compositions of the invention can be in the form of a tablet, capsule, powder, liquid, functional food, beverage or special use food.

Abstract translation: 本发明涉及包含大豆产品和活性免疫球蛋白的组合物，用于营养和对人类和动物的整体健康益处。 本发明的组合物可以是片剂，胶囊，粉末，液体，功能食品，饮料或特殊用途食品的形式。

公开(公告)号：WO1994006474A1

公开(公告)日：1994-03-31

申请号：PCT/US1993008736

申请日：1993-09-15

Applicant: GALAGEN INC.

Inventor： GALAGEN INC. ,  RUIZ, Leonard, P. ,  WALSH, Richard, M. ,  ROUSH, Anne, M. ,  BOSTWICK, Eileen, F.

IPC: A61K39/395

CPC classification number: C07K16/40 ,  G01N33/573

Abstract: The invention provides an antibody with specific activity to urease. Also provided is a pharmaceutical composition for use in a method of treatment for gastrointestinal disorders in an animal. The invention also provides methods for detecting and inhibiting (H. pylori) urease activity.

Abstract translation: 本发明提供了对脲酶具有特异活性的抗体。 还提供了用于在动物中治疗胃肠道疾病的方法中的药物组合物。 本发明还提供了用于检测和抑制（幽门螺杆菌）脲酶活性的方法。

公开(公告)号：WO1996032021A1

公开(公告)日：1996-10-17

申请号：PCT/US1996005110

申请日：1996-04-12

Applicant: GALAGEN, INC.

Inventor： GALAGEN, INC. ,  GREGORY, Antone, G.

IPC: A23C09/142

CPC classification number: A23J1/205 ,  A23C9/1425 ,  A23C9/206 ,  A23J1/20 ,  A23J3/08

Abstract: Ultrafiltration of whey containing products at an acid pH reduces calcium levels in the concentrate and provides a concentrate that can be consistently microfiltered. The concentrate can be used, for example, in a method of microfiltering milk, milk serum, colostrum, or colostral serum which provides effective bioburden reduction without substantial loss of immunoglobulins.

Abstract translation: 在酸性pH下含有乳清的产品的超滤可降低浓缩物中的钙含量，并提供可以一贯进行过滤的浓缩物。 浓缩物可以用于例如微乳过滤牛奶，乳清，初乳或初乳血清的方法，该方法提供有效的生物负载减少而不会显着损失免疫球蛋白。

公开(公告)号：WO1996007430A1

公开(公告)日：1996-03-14

申请号：PCT/US1995010335

申请日：1995-08-14

Applicant: GALAGEN, INC.

Inventor： GALAGEN, INC. ,  BOSTWICK, Eileen, F. ,  HOERR, Robert, A.

IPC: A61K39/40

CPC classification number: C07K16/1282 ,  A61K38/08 ,  A61K38/12 ,  A61K39/40 ,  A61K2300/00

Abstract: The effective treatment of Clostridium difficile associated diseases, such as Clostridium difficile colitis, pseudomembranous colitis and antibiotic associated diarrhea, by administering an antibody having specific activity against Clostridium difficile colitis and toxins thereof alone or in combination with vancomycin, bacitracin or metronidazole is herein described as well as pharmaceutical compositions therefor.

Abstract translation: 本文将通过施用具有针对艰难梭菌结肠炎特异性活性的抗体及其毒素单独使用或与万古霉素，杆菌肽或甲硝唑组合来有效治疗难辨梭状芽孢杆菌相关疾病，例如艰难梭菌结肠炎，假膜性结肠炎和抗生素相关性腹泻， 以及其药物组合物。