公开(公告)号：WO2005108552A1

公开(公告)日：2005-11-17

申请号：PCT/SE2005/000660

申请日：2005-05-04

Applicant: FORSKARPATENT I SYD AB ,  KARHUMAA, Kaisa ,  GORWA-GRAUSLUND, Marie-Françoise

Inventor： KARHUMAA, Kaisa ,  GORWA-GRAUSLUND, Marie-Françoise

IPC: C12N1/19

CPC classification number: C12P7/06 ,  C12N9/0006 ,  C12N9/1205 ,  C12N15/52 ,  C12P7/10 ,  C12Y207/01017 ,  Y02E50/16 ,  Y02E50/17

Abstract: The present invention relates to a new xylose utilizing Saccharomyces cerevisiae strain being able to utilize xylose for ethanol production which strain is up-regulated with regard to the genes for xylose reductase (XR) and xylulose dehydrogenase (XDH) as well as xululokinase (XK) and over-expressing the non-oxidative pentose phosphate pathway (PPP) and comprising a deletion of the gene GRE3 deletion, as well as the strain has been adapted to xylose feeding.

Abstract translation: 本发明涉及一种利用酿酒酵母菌株的新型木糖能够利用木糖进行乙醇生产，其中木糖还原酶（XR）和木酮糖脱氢酶（XDH）以及xululokinase（XK）的基因都被上调， 并且过表达非氧化戊糖磷酸途径（PPP）并且包含基因GRE3缺失的缺失，以及该菌株已被适应于木糖喂养。

公开(公告)号：WO2005093041A1

公开(公告)日：2005-10-06

申请号：PCT/SE2005/000453

申请日：2005-03-24

Applicant: FORSKARPATENT I SYD AB ,  GORWA-GRAUSLUND, Marie-Françoise ,  JEPPSON, Marie

Inventor： GORWA-GRAUSLUND, Marie-Françoise ,  JEPPSON, Marie

IPC: C12N1/19

CPC classification number: C12P7/06 ,  C12N9/0004 ,  Y02E50/17

Abstract: New xylose-utilizing Saccharomyces cerevisiae mutant strain which ferments xylose to ethanol, wherein the strain expresses a K270M mutated P. stipitis XYL1 gene (1 or 2 copies of the mutated gene) together with the native P. stipitis XYL2 gene and overexpresses the endogenous XKS1 gene.

Abstract translation: 新型木糖利用的酿酒酵母突变菌株将木糖发酵成乙醇，其中菌株表达了K270M突变的树干特有的XYL1基因（突变基因的1或2个拷贝）以及天然的白喉树木XYL2基因，并且过表达内源性XKS1 基因。