公开(公告)号：WO2008075265A1

公开(公告)日：2008-06-26

申请号：PCT/IB2007/055080

申请日：2007-12-13

Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  HARVEY, Paul, R.

Inventor： HARVEY, Paul, R.

IPC: G01R33/567 ,  G01R33/565

CPC classification number: G01R33/56509 ,  G01R33/481

Abstract: A diagnostic imaging arrangement comprises a magnetic resonance examination (1) system to acquire magnetic resonance signals and an emission tomography system (2) to acquire nuclear decay signals. An analysis module (4) is provided to derive motion correction(s) from the magnetic resonance signals. A reconstruction module (5) reconstructs a motion corrected emission tomographic image from the nuclear decay signals on the basis of the motion correction. Also a therapeutic arrangement is disclosed with a diagnostic imaging arrangement and a therapy module, with a system controller is further coupled to the therapy module and has the function to control the therapy module on the basis of image information generated by the diagnostic imaging system.

Abstract translation: 诊断成像装置包括用于获取磁共振信号的磁共振检查（1）系统和用于获取核衰变信号的发射断层摄影系统（2）。 提供分析模块（4）以从磁共振信号导出运动校正。 重建模块（5）基于运动校正从核衰减信号重建运动校正的发射断层图像。 还公开了具有诊断成像装置和治疗模块的治疗装置，系统控制器进一步耦合到治疗模块，并且具有基于由诊断成像系统生成的图像信息来控制治疗模块的功能。

公开(公告)号：WO2008023314A2

公开(公告)日：2008-02-28

申请号：PCT/IB2007/053290

申请日：2007-08-17

Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  PANANAKIS, Dimitrios ,  HARVEY, Paul, R.

Inventor： PANANAKIS, Dimitrios ,  HARVEY, Paul, R.

IPC: A61B5/00 ,  A61N1/00

CPC classification number: A61N1/403 ,  A61B5/015 ,  A61B5/055 ,  G01R33/4804

Abstract: This invention relates to a device for retrieving information about one or more states of a mammalian body comprising: (a) a magnetic resonance imaging device comprising a first set of one or more radio-frequency coils for measuring the body temperature Ti at a selected location of a mammalian body, (b) a local heating means including a second set of one or more radio-frequency coils, said second set comprising at least two channels for delivering focused radio frequency energy to said selected location of said mammalian body and raising the temperature Ti thereof, and (c) means for modulating said radio-frequency energy delivered by said second set of coils as a function of said temperature Ti in order to reach and maintain a predefined temperature Tp above the normal mammalian body temperature Tb.

Abstract translation: 本发明涉及一种用于检索关于哺乳动物身体的一种或多种状态的信息的设备，包括：（a）磁共振成像设备，其包括用于测量哺乳动物身体的一个或多个状态的第一组一个或多个射频线圈 （b）包括第二组一个或多个射频线圈的局部加热装置，所述第二组包括至少两个通道，用于将聚焦射频能量传送到所述选定位置 以及（c）用于调制由所述第二组线圈输送的所述射频能量作为所述温度T i的函数的装置，以便达到并保持高于所述哺乳动物体的温度T 1的预定温度T p 正常哺乳动物体温Tb。

公开(公告)号：WO2006137026A2

公开(公告)日：2006-12-28

申请号：PCT/IB2006/052003

申请日：2006-06-21

Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH ,  HARVEY, Paul, R. ,  GRAESSLIN, Ingmar ,  LEUSSLER, Christoph

Inventor： HARVEY, Paul, R. ,  GRAESSLIN, Ingmar ,  LEUSSLER, Christoph

IPC: G01R33/36 ,  G01R33/3415

CPC classification number: G01R33/3415 ,  G01R33/3635

Abstract: The invention relates to an MR device (1) for magnetic resonance imaging of a body (14) placed in an examination volume (7), the device (1) comprising a main magnet (2) for generating a stationary and substantially homogeneous main magnetic field in the examination volume (7), and an RF coil arrangement for generating RF fields in the examination volume (7) and/or for receiving MR signals from the body (14). In order to provide such an MR device, which is arranged to operate at the resonance (Larmor) frequencies of two or more different nuclear species at the same time, the invention suggests that the RF coil arrangement comprises a plurality of independent resonator elements (8, 9, 10, 11, 12, 13) which are adjacently arranged in or near the examination volume (7), wherein adjacent resonator elements (8, 9, 10, 11, 12, 13) are alternately tuned to one of two or more different MR resonance frequencies, and wherein each resonator element (8, 9, 10, 11, 12, 13) is associated with a separate signal transmission (16) and/or signal reception channel (17) of the MR device (1)

Abstract translation: 本发明涉及用于放置在检查体积（7）中的体（14）的磁共振成像的MR装置（1），所述装置（1）包括主磁体（2），用于产生静止且基本均匀的主磁 在检查体积（7）中的场和用于在检查体积（7）中产生RF场和/或用于从身体（14）接收MR信号的RF线圈装置。 为了提供这样的MR器件，其被布置为在同时在两个或更多个不同核物质的共振（Larmor）频率下操作，本发明提出RF线圈装置包括多个独立的谐振元件（8 ，9,10,11,12,13），其相邻地布置在检查体积（7）中或附近，其中相邻的谐振器元件（8,9,10,11,12,13）交替地被调谐到两个或 更多不同的MR谐振频率，并且其中每个谐振器元件（8,9,10,11,12,13）与MR装置（1）的单独信号传输（16）和/或信号接收通道（17）相关联，

公开(公告)号：WO2006003580A1

公开(公告)日：2006-01-12

申请号：PCT/IB2005/052097

申请日：2005-06-24

Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  HARVEY, Paul, R. ,  PEEREN, Gerardus, N.

Inventor： HARVEY, Paul, R. ,  PEEREN, Gerardus, N.

IPC: G01R33/385

CPC classification number: G01R33/385

Abstract: The present invention relates to a magnetic resonance imaging (MRI) device and to a method for operating it. The basic components of an MRI device are the main magnet system (2) for generating a steady magnetic field, the gradient system (3) with at least one gradient coil, the RF system and the signal processing system. According to the present invention, the gradient coil is split into sub-coils (S1, S2) at least in the direction of the steady magnetic field. By doing so, the amplitude of the non-imaging component of the gradient field in the vicinity of the patient is reduced, leading to reduced peripheral nerve stimulation and thus enhanced image quality.

Abstract translation: 本发明涉及一种磁共振成像（MRI）装置及其操作方法。 MRI装置的基本部件是用于产生稳定磁场的主磁体系统（2），具有至少一个梯度线圈的梯度系统（3），RF系统和信号处理系统。 根据本发明，梯度线圈至少在稳定磁场的方向上分成子线圈（S1，S2）。 通过这样做，患者附近的梯度场的非成像成分的振幅减小，导致周围神经刺激减弱，从而提高图像质量。

公开(公告)号：WO2005088328A2

公开(公告)日：2005-09-22

申请号：PCT/IB2005/050681

申请日：2005-02-24

Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  HARVEY, Paul, R. ,  KRUGER, Luc, R. ,  SLEGT, Sander

Inventor： HARVEY, Paul, R. ,  KRUGER, Luc, R. ,  SLEGT, Sander

IPC: G01R33/20

CPC classification number: G01R33/543 ,  G01R33/546 ,  G01R33/56375

Abstract: The present invention provides a magnetic resonance imaging system making use of low resolution, whole-body plan scan image of a body. The whole-body plan scan image is exploited to gather a plurality of individual information of a body that is essential for an optimization of acquisition parameter for acquisition of a high resolution and high quality image of a region of interest of the body. Moreover, the whole-body plan scan image is used in order to facility a determination and a selection of a region of interest to be performed by an operator. Additionally, the MRI provides effective means for autonomously identifying specific body parts or even organs of a patient. Providing the entire information that can be extracted from the whole-body plan scan image to the operator effectively simplifies the workflow of the operator in an intuitive way. Preferably, during acquisition of the low resolution whole-body plan scan image, necessary calibration parameters for acquisition of the final high resolution image are obtained.

Abstract translation: 本发明提供使用身体的低分辨率，全身平面扫描图像的磁共振成像系统。 全身计划扫描图像被利用来收集身体的多个个体信息，该身体对于获取身体的感兴趣区域的高分辨率和高质量图像的获取参数的优化是必不可少的。 此外，使用全身平面扫描图像来进行由操作者执行的感兴趣区域的确定和选择。 此外，MRI提供了用于自主识别患者的特定身体部位甚至器官的有效手段。 将能够从全身计划扫描图像提取的全部信息提供给操作者有效地以直观的方式简化了操作者的工作流程。 优选地，在获取低分辨率全身平面扫描图像期间，获得用于获取最终高分辨率图像的必要的校准参数。

公开(公告)号：WO2005003802A1

公开(公告)日：2005-01-13

申请号：PCT/IB2004/051102

申请日：2004-07-02

Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  HARVEY, Paul, R.

Inventor： HARVEY, Paul, R.

IPC: G01R33/389

CPC classification number: G01R33/389 ,  G01R33/56563

Abstract: The invention enables to monitor a magnetic field drift of a magnetic resonance imaging apparatus on the basis of the magnetic resonance signals, which are acquired during magnetic resonance image data acquisition, such as by single shot EPI or by a gradient echo sequence. The phases of at least two magnetic resonance signals are acquired an echo time after the corresponding RF excitations. This corresponds to the central k-space line, which has frequency encoding but no phase encoding. The difference of two consecutive phase measurements, which are acquired at a certain time interval provides the shift of the resonance frequency. This enables monitoring of the shift of the resonance frequency and compensation of the magnetic field drift.

Abstract translation: 本发明能够基于在磁共振图像数据采集期间例如通过单次EPI或梯度回波序列获取的磁共振信号来监测磁共振成像装置的磁场漂移。 在相应的RF激励之后获取至少两个磁共振信号的相位。 这对应于具有频率编码但没有相位编码的中心k空间线。 在一定时间间隔获得的两个连续相位测量的差异提供了共振频率的偏移。 这使得能够监测谐振频率的偏移和磁场漂移的补偿。

公开(公告)号：WO2004046744A1

公开(公告)日：2004-06-03

申请号：PCT/IB2003/004816

申请日：2003-10-27

Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  ROOZEN, Nicolaas, B. ,  HAM, Cornelis, L., G. ,  HARVEY, Paul, R. ,  LIMPENS, Patrick, W., P.

Inventor： ROOZEN, Nicolaas, B. ,  HAM, Cornelis, L., G. ,  HARVEY, Paul, R. ,  LIMPENS, Patrick, W., P.

IPC: G01R33/385

CPC classification number: G01R33/3854

Abstract: The invention relates to a magnetic resonance imaging (MRI) system (1) comprising an examination volume (11), a main magnet system (13) for generating a main magnetic field (B 0 ) in the examination volume in a Z-direction, a gradient magnet system (19) for generating gradients of the main magnetic field, and an anti-vibration system (33) for reducing vibrations of the gradient magnet system caused by a mechanical load (M X , M Y ) exerted on the gradient magnet system as a result of electromagnetic interaction between the main magnetic field and electrical currents in the gradient magnet system. According to the invention the anti-vibration system (33) comprises a balance member (39), which is coupled to the gradient magnet system (19) by means of an actuator system (51) and a coupling device (49) allowing displacements of the balance member relative to the gradient magnet system. The MRI system (1) also has a control system (81) which controls the actuator system in such a manner that the actuator system exerts upon the balance member a compensating mechanical load (M CX , M CY ) which substantially corresponds to the mechanical load (M X , M Y ) exerted on the gradient magnet system. As a result, the actuator system exerts a mechanical reaction load (M RX , M RY ) on the gradient magnet system which has the same magnitude as but is oppositely directed to the mechanical load (M X , M Y ) exerted on the gradient magnet system, so that vibrations of the gradient magnet system are effectively limited.

Abstract translation: 本发明涉及一种磁共振成像（MRI）系统（1），包括检查体积（11），主磁体系统（13），用于在Z轴中产生检查体积中的主磁场（B> 0 < 方向，用于产生主磁场梯度的梯度磁体系统（19）和用于减少由机械载荷引起的梯度磁体系统振动的防振系统（33）（M> X < ）作为梯度磁体系统中的主磁场和电流之间的电磁相互作用的结果施加在梯度磁体系统上。 根据本发明，防振系统（33）包括平衡构件（39），其通过致动器系统（51）和耦合装置（49）耦合到梯度磁体系统（19），耦合装置（49）允许位移 平衡构件相对于梯度磁体系统。 MRI系统（1）还具有控制系统（81），该控制系统（81）控制致动器系统，使得致动器系统在平衡构件上施加补偿机械载荷（M> CX <，M> CY < 到施加在梯度磁体系统上的机械载荷（M> X <，M> Y <）。 因此，致动器系统在梯度磁体系统上施加机械反作用力（M> RX <，M> RY <），其具有与机械载荷相同而相反的机械载荷（M> X，M> Y <）施加在梯度磁体系上，从而有效地限制了梯度磁体系的振动。

公开(公告)号：WO2004027443A1

公开(公告)日：2004-04-01

申请号：PCT/IB2003/003542

申请日：2003-08-08

Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  HARVEY, Paul, R.

Inventor： HARVEY, Paul, R.

IPC: G01R33/54

CPC classification number: G01R33/54

Abstract: The invention provides a method and a magnetic resonance imaging apparatus where cyclic image data acquisition is performed while the patient is continuously moved through the imaging volume provided by the magnetic field. The volume to be imaged is subdivided into sub-volumes. Image data acquisitions are sequentially performed for the sub-volumes. The data acquisition for a given sub-volume is performed by true three-dimensional imaging or by a multi slice imaging method where the sub-volume contains a stack of two-dimensional slices. The sub-volume for which image data acquisition is performed is moved through the magnetic field together with the patient. When the image data acquisition for the sub-volume has been completed, the next image data acquisition starts for the subsequent sub-volume.

Abstract translation: 本发明提供了一种方法和磁共振成像装置，其中当患者连续移动通过由磁场提供的成像体积时执行循环图像数据采集。 要成像的体积被细分为子体积。 顺序对子卷执行图像数据采集。 给定子体积的数据采集是通过真正的三维成像或通过多层成像方法进行的，其中子体积包含二维切片的堆叠。 执行图像数据采集的子体积与患者一起移动通过磁场。 当子卷的图像数据采集已经完成时，对于后续的子卷开始下一图像数据采集。

公开(公告)号：WO2003046597A1

公开(公告)日：2003-06-05

申请号：PCT/IB2002/004871

申请日：2002-11-20

Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  HAM, Cornelis, L., G. ,  HARVEY, Paul, R.

Inventor： HAM, Cornelis, L., G. ,  HARVEY, Paul, R.

IPC: G01R33/385

CPC classification number: G01R33/3854 ,  G01R33/3415 ,  G01R33/5611

Abstract: A magnetic resonance imaging method comprises application of a pulse sequence which includes one or more pulses. The pulse sequence having an intrinsic scan time based on a full sampling rate in k-space for a predetermined full ' field-of-view' and a reference temporal pulse shape of the magnetic gradient pulses. A series of magnetic resonance signals is acquired by means of a receiver antennae system having a spatial sensitivity profile. Undersampled signal acquisition is applied to acquire undersampled magnetic resonance signals at a predetermined reduced sampling rate in k-space, the sampling rate being reduced by a reduction factor relative the full sampling rate. The pulse sequence being is during an actual signal scan time is applied. The actual signal scan time being larger than the intrinsic signal scan time times the reduction factor. The undersampling allows a smaller acquisition rate of the magnetic resonance signals and smaller slew rates and amplitudes of the magnetic gradient pulses and lower peak RF-fields of the refocusing pulses. Hence, lower acoustic noise and lower specific absorption rate are achieved.

Abstract translation: 磁共振成像方法包括施加包括一个或多个脉冲的脉冲序列。 脉冲序列具有基于k空间中的预定全“视场”的全采样率的本征扫描时间和磁梯度脉冲的参考时间脉冲形状。 通过具有空间灵敏度分布的接收机天线系统获得一系列磁共振信号。 应用未采样信号采集以在k空间中以预定的降低的采样率获取欠采样的磁共振信号，采样速率相对于全采样率减小减小因子。 脉冲序列是在实际的信号扫描时间期间。 实际信号扫描时间大于固有信号扫描时间乘以缩小因子。 欠采样允许较小的磁共振信号的采集速率和更小的转换速率和磁梯度脉冲的幅度以及重聚焦脉冲的较低峰值RF场。 因此，实现了较低的声学噪声和较低的比吸收率。

公开(公告)号：WO2011033401A1

公开(公告)日：2011-03-24

申请号：PCT/IB2010/053556

申请日：2010-08-05

Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  HARVEY, Paul, R. ,  ROZIJN, Thomas, H. ,  IJPEREN, Gerrit, H. ,  PRINS, Willem, M. ,  MENS, Wilhelmus, R., M. ,  BENSCHOP, Franciscus, J., M.

Inventor： HARVEY, Paul, R. ,  ROZIJN, Thomas, H. ,  IJPEREN, Gerrit, H. ,  PRINS, Willem, M. ,  MENS, Wilhelmus, R., M. ,  BENSCHOP, Franciscus, J., M.

IPC: G01R33/565

CPC classification number: G01R33/5659

Abstract: A magnetic resonance system comprises : a magnetic resonance scanner including a multi-channel transmit coil or coil system and a magnetic resonance receive element; and a digital processor configured to perform an imaging process including shimming the multi-channel transmit coil or coil system, acquiring a coil sensitivity map for the magnetic resonance receive element using the multi-channel transmit coil or coil system, acquiring a magnetic resonance image using the magnetic resonance receive element and the shimmed multi-channel transmit coil or coil system, and performing an intensity level correction on the acquired magnetic resonance image using the coil sensitivity map to generate a corrected magnetic resonance image.

Abstract translation: 磁共振系统包括：包括多通道发射线圈或线圈系统和磁共振接收元件的磁共振扫描器; 以及数字处理器，被配置为执行包括对多通道发射线圈或线圈系统进行匀场的成像处理，使用多通道发射线圈或线圈系统获取用于磁共振接收元件的线圈灵敏度图，使用 所述磁共振接收元件和所述散光多通道发射线圈或线圈系统，并且使用所述线圈灵敏度映射对获取的磁共振图像执行强度电平校正，以产生校正的磁共振图像。