公开(公告)号：WO2003044487A1

公开(公告)日：2003-05-30

申请号：PCT/SE2002/002098

申请日：2002-11-19

Applicant: BIOSENSOR APPLICATIONS SWEDEN AB ,  MÅNSSON, Per ,  SMITH, Jan ,  HELLGREN, Ann-Charlotte

Inventor： MÅNSSON, Per ,  SMITH, Jan ,  HELLGREN, Ann-Charlotte

IPC: G01N1/22

CPC classification number: G01N1/40 ,  G01N2001/2282 ,  G01N2001/383 ,  G01N2001/4033

Abstract: An apparatus (10) and a method for concentrating and transferring volatile compounds contained in a sample on a detachable solid support (12) into a liquid for subsequent detection and/or analysis of the volatile compounds, are described. The apparatus comprises a holder (14) for the solid support (12), means (16) for transporting the holder (14) to a heating position on a heatable plate (18), a closed room-creating arrangement comprising the heatable plate (18) attached to a movable housing (30), the holder (14), the solid support (12), a funnel (20) on the solid support (12), and inside the funnel (20) a cold spot (22), means inside the housing (30) for heating the heatable plate (18) to evaporate the volatile compounds which then are condensed on the cold spot (22), means (24) for transporting the cold spot (22) from a cooler (26) to the inside of the funnel (20) and from there to a position (28) where condensed compounds are removed from the cold spot (22) into a liquid.

Abstract translation: 描述了用于将包含在样品中的挥发性化合物浓缩并转移到可分离的固体支持物（12）上的装置（10）和用于随后检测和/或分析挥发性化合物的液体的方法。 该设备包括用于固体支撑件（12）的保持器（14），用于将保持器（14）运送到可加热板（18）上的加热位置的装置（16），包括可加热板 18），固定支架（12），固体支撑件（12）上的漏斗（20），漏斗（20）内的冷点（22）， ，用于加热可加热板（18）以蒸发在冷点（22）上冷凝的挥发性化合物的装置（30）内的装置，用于将冷点（22）从冷却器（26）输送的装置 ）到漏斗（20）的内部并从那里到达冷凝化合物从冷点（22）去除成液体的位置（28）。

公开(公告)号：WO2005050209A1

公开(公告)日：2005-06-02

申请号：PCT/SE2004/001697

申请日：2004-11-19

Applicant: BIOSENSOR APPLICATIONS SWEDEN (PUBL) ,  MÅNSSON, Per ,  BERGGREN, Daniel ,  LUNDBERG, Carl ,  HELLGREN, Ann-Charlotte ,  HÖJVALL, Lena

Inventor： MÅNSSON, Per ,  BERGGREN, Daniel ,  LUNDBERG, Carl ,  HELLGREN, Ann-Charlotte ,  HÖJVALL, Lena

IPC: G01N33/543

CPC classification number: G01N29/022 ,  G01N29/222 ,  G01N2291/0255 ,  G01N2291/0256 ,  G01N2291/0426

Abstract: A mixture of isolated or synthetic affinity molecules in a liquid carrier is disclosed. The mixture comprises at least two different affinity molecules, each with affinity for a predetermined analyte, for use in a single or multi flow cell piezoelectric crystal micro balance apparatus. Each isolated or synthetic affinity molecule forms molecule forms together with the predetermined analyte an interaction pair selected from the group consisting of anion-cation, antibody-antigen, receptor-ligand, enzyme-substrate, oligonucleotide-oligonucleotide with complementary sequence, oligonucleotide-protein, oligonucleotide-cell, and peptide nucleic acid (PNA) oligomer - polynucleotide, wherein the polynucleotide may be selected from the group consisting of RNA, DNA and PNA polymers complementary to the PNA oligomer. Use of the mixture for introduction into the liquid flow of a single or multi flow cell piezoelectric crystal micro balance apparatus is also described, as well as a kit containing the mixture.

Abstract translation: 公开了液体载体中分离的或合成的亲和分子的混合物。 该混合物包含至少两种不同的亲和力分子，各自对于预定的分析物具有亲和力，用于单流或多流量单元压电晶体微量平衡装置。 每个分离或合成的亲和分子与预定分析物一起形成分子形式，所述分子形式选自阴离子阳离子，抗体 - 抗原，受体 - 配体，酶 - 底物，具有互补序列的寡核苷酸 - 寡核苷酸，寡核苷酸 - 蛋白质， 寡核苷酸细胞和肽核酸（PNA）寡聚体 - 多核苷酸，其中多核苷酸可以选自与PNA低聚物互补的RNA，DNA和PNA聚合物。 还描述了将混合物引入单流动池或多流通池压电晶体微量平衡装置的液体流中的用途，以及含有该混合物的试剂盒。

公开(公告)号：WO2003073070A1

公开(公告)日：2003-09-04

申请号：PCT/SE2003/000319

申请日：2003-02-26

Applicant: BIOSENSOR APPLICATIONS SWEDEN AB (PUBL) ,  HELLGREN, Ann-Charlotte ,  JENSEN, Kjeld ,  ENG, Lars ,  JOHANSSON, Marita ,  MÅNSSON, Per

Inventor： HELLGREN, Ann-Charlotte ,  JENSEN, Kjeld ,  ENG, Lars ,  JOHANSSON, Marita ,  MÅNSSON, Per

IPC: G01N1/22

CPC classification number: B01D39/2017 ,  B01D39/1623 ,  G01N2001/2826

Abstract: Thermostable coated filter disks for adsorption/desorption of gaseous analytes from air, wherein the filter pore walls are coated with a thermostable polymer, are described. Further, amethod of concentrating small amounts of gaseous analytes from air for further analysis is disclosed. Additionally, use of the thermostable filter disks for adsorption and desorption of gaseous analytes, such as explosives and narcotics is comprised by the disclosure.

Abstract translation: 描述了用于从空气中吸附/解吸气态分析物的热稳定涂层过滤盘，其中过滤器孔壁涂覆有耐热聚合物。 此外，公开了从空气中浓缩少量气态分析物进行进一步分析的方法。 此外，本公开内容包括使用热稳定性过滤盘来吸附和解吸气体分析物，例如爆炸物和麻醉剂。