公开(公告)号：WO2009147221A1

公开(公告)日：2009-12-10

申请号：PCT/EP2009/056897

申请日：2009-06-04

Applicant: BIOVITRUM AB (publ) ,  SIMPSON, Iain ,  HIGGINBOTTOM, Michael ,  CHAPMAN, Emma ,  HORGAN, Anne Viet-Anh (nee Nguyen)

Inventor： SIMPSON, Iain ,  HIGGINBOTTOM, Michael ,  CHAPMAN, Emma ,  HORGAN, Anne Viet-Anh (nee Nguyen)

IPC: C07D213/30 ,  C07D405/12 ,  C07D413/12 ,  C07D295/088 ,  A61K31/495 ,  A61P3/04

CPC classification number: C07D295/088 ,  C07D213/30 ,  C07D405/12 ,  C07D413/12

Abstract: The present invention relates to new compounds of formula (I), to pharmaceutical compositions comprising these compounds and to the use of these compounds as leptin receptor modulator mimetics in the preparation of medicaments against conditions associated with weight gain, type 2 diabetes and dyslipidemias.

Abstract translation: 本发明涉及新的式（I）化合物，包含这些化合物的药物组合物以及这些化合物作为瘦素受体调节剂模拟物在制备与增重，2型糖尿病和血脂异常相关的病症的药物中的用途。

公开(公告)号：WO2009147219A1

公开(公告)日：2009-12-10

申请号：PCT/EP2009/056892

申请日：2009-06-04

Applicant: BIOVITRUM AB (publ) ,  SIMPSON, Iain ,  HIGGINBOTTOM, Michael ,  HORGAN, Anne Viet-Anh (nee Nguyen) ,  CHAPMAN, Emma

Inventor： SIMPSON, Iain ,  HIGGINBOTTOM, Michael ,  HORGAN, Anne Viet-Anh (nee Nguyen) ,  CHAPMAN, Emma

IPC: C07D211/34 ,  A61K31/445 ,  A61P3/04

CPC classification number: C07D211/34

Abstract: The present invention relates to new compounds of formula (I), to pharmaceutical compositions comprising these compounds and to the use of these compounds as leptin receptor modulator mimetics in the preparation of medicaments against conditions associated with weight gain, type 2 diabetes and dyslipidemias.

Abstract translation: 本发明涉及新的式（I）化合物，包含这些化合物的药物组合物以及这些化合物作为瘦素受体调节剂模拟物在制备与增重，2型糖尿病和血脂异常相关的病症的药物中的用途。

公开(公告)号：WO2009147211A1

公开(公告)日：2009-12-10

申请号：PCT/EP2009/056877

申请日：2009-06-04

Applicant: BIOVITRUM AB (publ) ,  HIGGINBOTTOM, Michael ,  SIMPSON, Iain ,  HORTON, James ,  TYZACK, Charles ,  HORGAN, Anne Viet-Anh (nee Nguyen) ,  CHAPMAN, Emma

Inventor： HIGGINBOTTOM, Michael ,  SIMPSON, Iain ,  HORTON, James ,  TYZACK, Charles ,  HORGAN, Anne Viet-Anh (nee Nguyen) ,  CHAPMAN, Emma

IPC: A61K31/4439 ,  A61K31/4545 ,  A61K31/496 ,  A61K31/5377 ,  C07D213/30 ,  C07D213/40 ,  C07D401/12 ,  C07D413/12 ,  A61P3/00

CPC classification number: C07D213/30 ,  C07D213/40 ,  C07D401/12 ,  C07D413/12

Abstract: The present invention relates to new compounds of formula (I), to pharmaceutical compositions comprising these compounds and to the use of these compounds as leptin receptor modulator mimetics in the preparation of medicaments against conditions associated with weight gain, type 2 diabetes and dyslipidemias.

Abstract translation: 本发明涉及新的式（I）化合物，包含这些化合物的药物组合物以及这些化合物作为瘦素受体调节剂模拟物在制备与增重，2型糖尿病和血脂异常相关的病症的药物中的用途。