公开(公告)号：WO2007103110A2

公开(公告)日：2007-09-13

申请号：PCT/US2007/005261

申请日：2007-03-02

Applicant: IP-6 RESEARCH INC. ,  SHAMSUDDIN, Abulkalam, M. ,  VON FRAUNHOFER, Joseph, A.

Inventor： SHAMSUDDIN, Abulkalam, M. ,  VON FRAUNHOFER, Joseph, A.

IPC: A23L1/30

CPC classification number: A23L2/52 ,  A23V2002/00 ,  A23V2200/312 ,  A23V2250/641

Abstract: The present invention provides compositions of inositol and derivatives and their salts and related compounds which reduce titratable acidity and the erosive potential of a variety of beverages and foodstuffs. Further, as a result of its protective action towards acid attack on dental enamel (hydroxyapatite), its addition to foodstuffs has a protective action towards the hard dental tissues. The compositions also provide protection against other metabolic/degenerative diseases of bones such as osteoporosis. The present invention further provides methods for preventing dental decay and bone degeneration.

Abstract translation: 本发明提供肌醇及其衍生物及其盐和相关化合物的组合物，其降低各种饮料和食品的滴定酸度和腐蚀潜能。 此外，由于其对牙釉质（羟基磷灰石）的酸侵蚀的保护作用，其对食品的添加对硬牙组织具有保护作用。 所述组合物还提供了抵抗骨骼诸如骨质疏松症的其它代谢/变性疾病的保护。 本发明还提供了防止牙齿腐烂和骨退化的方法。

公开(公告)号：WO2007079177A2

公开(公告)日：2007-07-12

申请号：PCT/US2006/049477

申请日：2006-12-29

Applicant: IP-6 RESEARCH INC. ,  COPPOLINO, Carl, A. ,  SHAMSUDDIN, Abulkalam, M.

Inventor： COPPOLINO, Carl, A. ,  SHAMSUDDIN, Abulkalam, M.

IPC: A61K31/663 ,  C07F9/02

CPC classification number: C07F9/093 ,  C07F9/096 ,  C07F9/117

Abstract: The present invention provides a chemical compound or a salt thereof having the chemical formula of: formula (I) wherein said R is H or citrate and wherein at least one R is citrate. The salt of the chemical compound is the Na + , K + , Mg 2+ , or Ca 2+ salt of said chemical compound. The chemical compound is a chelator which chelates sodium, potassium or lithium, magnesium, calcium, copper, iron, lead, zinc, aluminum, mercury, cadmium, or chromium. It is also be used as an artery plaque dissolver and/or to treat age-related degenerative disorders, such as Alzheimer's disease. The present invention also provides a method for producing the phytic citrate compound and/or its salt.

Abstract translation: 本发明提供具有化学式为：式（I）的化合物或其盐，其中所述R是H或柠檬酸盐，并且其中至少一个R是柠檬酸盐。 化合物的盐为Na +，K +，SO 2 +，或+ 2 + 所述化合物的盐。 该化合物是螯合剂，它螯合钠，钾或锂，镁，钙，铜，铁，铅，锌，铝，汞，镉或铬。 它还可用作动脉斑块溶解器和/或治疗年龄相关的退行性疾病，例如阿尔茨海默病。 本发明还提供了一种生产植酸柠檬酸化合物和/或其盐的方法。