Abstract:
The present invention relates to an anti-inflammatory composition using an antibody specifically binding to CD93 or a soluble fragment thereof, a method for diagnosing inflammatory diseases using an aptamer or an antibody specifically binding to CD93 or a soluble fragment thereof, and a kit for diagnosing inflammatory diseases.
Abstract:
The present invention relates to a transmembrane protease, serine (TMPRSS4) -specific human antibody, and more particularly to a human antibody including a complementarity determining region (CDR) and a framework region (FR) derived from a human antibody specifically bound to TMPRSS4. The TMPRSS4- specific human antibody expressed in the various kinds of cancer cells of the present invention may be used in diagnosis of the cancer, classification of the disease, visualization, treatment, and prognostic evaluation.
Abstract:
The present invention relates to an anti-inflammatory composition using an antibody specifically binding to CD93 or a soluble fragment thereof, a method for diagnosing inflammatory diseases using an aptamer or an antibody specifically binding to CD93 or a soluble fragment thereof, and a kit for diagnosing inflammatory diseases.
Abstract:
The present invention relates to a transmembrane protease, serine (TMPRSS4) -specific human antibody, and more particularly to a human antibody including a complementarity determining region (CDR) and a framework region (FR) derived from a human antibody specifically bound to TMPRSS4. The TMPRSS4- specific human antibody expressed in the various kinds of cancer cells of the present invention may be used in diagnosis of the cancer, classification of the disease, visualization, treatment, and prognostic evaluation.
Abstract:
The present invention relates to a vascular endothelial growth factor (VEGF) -specific human antibody, and more particularly to a human antibody including a complementarity determining region (CDR) and a framework region (FR) derived from a human antibody specifically bound to VEGF. The VEGF- specific human antibody of the present invention may be used in diagnosis of diseases caused by the VEGF-overexpression, classification of the diseases, visualization, treatment, and prognostic evaluation.
Abstract:
The present invention relates to human monoclonal antibodies neutralizing vascular endothelial growth factor receptor and the use thereof. More specifically, relates to human ScFv molecules neutralizing vascular endothelial growth factor receptor, and a composition for inhibiting angiogenesis and a composition for treating cancer, which contain the human ScFv molecules. The disclosed monoclonal antibody neutralizing vascular endothelial growth factor receptor shows excellent neutralizing ability in living cells, compared to that of a commercially available antibody against vascular endothelial growth factor receptor, and shows the ability to neutralize vascular endothelial growth factor receptor not only in humans, but also in mice and rats. Thus, the monoclonal antibody will be useful in anticancer studies and will be highly effective in cancer treatment.
Abstract:
The present invention relates to a pillar for assembly type furniture. The pillar for assembly type furniture includes: a first pillar having a first top surface contacting a ceiling and a first bottom surface having an area less than that of the top surface; a second pillar having a second top surface having the same area as the first top surface and a second bottom surface having the same area as the first bottom surface, the second pillar having a first coupling hole in which the first pillar having the first bottom surface is inserted by a predetermined length in a length direction from the second top surface; a third pillar having a third top surface having the same area as the second top surface and a third bottom surface contacting the ground, the third pillar having a second coupling hole in which the second pillar having the second bottom surface is inserted by a predetermined length in a length direction from the third top surface; and an elastic member disposed in at least one coupling hole of the first coupling hole and the second coupling hole to apply a restoring force in a direction opposite to the direction in which the first or second pillar is inserted into the corresponding coupling hole.