公开(公告)号：WO2009153115A1

公开(公告)日：2009-12-23

申请号：PCT/EP2009/056091

申请日：2009-05-19

Applicant: UNILEVER PLC ,  UNILEVER N.V. ,  HINDUSTAN UNILEVER LIMITED ,  JOUSSE, Fabien, Frederic, Raymond, Marie ,  ROSSETTI, Damiano ,  TETRADIS-MAIRIS, Georgios

Inventor： JOUSSE, Fabien, Frederic, Raymond, Marie ,  ROSSETTI, Damiano ,  TETRADIS-MAIRIS, Georgios

IPC: B01F3/08 ,  B01F13/00 ,  B01F13/10 ,  B01F15/02

CPC classification number: B01F13/0062 ,  B01F3/0807 ,  B01F13/1013 ,  B01F13/1022 ,  B01F15/0203

Abstract: The drawbacks with existing commercial emulsion manufacture technology "are the lack of control over emulsion droplet size and the tendency towards polydisperse emulsion droplet size distributions. It is also very difficult to produce well-defined multiple emulsions. An apparatus is provided for manufacturing an emulsion product which overcomes, amongst other things, these problems comprising: (a) a plurality of elements (201), wherein each element (201) comprises a first microfluidic conduit (202) for carrying a first liquid stream and a second microfluidic conduit (203) for carrying a second liquid stream, the first microfluidic conduit (202) and second microfluidic conduit (203) intersecting at a junction (204) thereby to produce an emulsion product stream from the first liquid stream and the second liquid stream, and a microfluidic emulsion product conduit (205) for carrying the emulsion product stream away from the junction (204); (b) a non-microfluidic first manifold (301) in fluid communication with the plurality of first microfluidic conduits (202); and (c) a non-microfluidic second manifold (302) in fluid communication with the plurality of second microfluidic conduits (203); wherein the non-microfluidic first manifold (301) and the non-microfluidic second manifold (302) are in fluid communication with respectively a first closeable manifold drain (304) and a second closeable manifold drain (305). A method for manufacturing an emulsion product using the aforementioned apparatus is also provided.

Abstract translation: 现有商业乳液制造技术的缺点是缺乏对乳液液滴尺寸的控制和多分散乳液液滴尺寸分布的趋势，制备明确的多重乳液也是非常困难的，提供了一种用于制造乳液产品的装置 其克服了以下问题，其中包括：（a）多个元件（201），其中每个元件（201）包括用于承载第一液体流的第一微流体导管（202）和第二微流体导管（203） 用于携带第二液体流，第一微流体导管（202）和第二微流体导管（203）在连接处相交，从而产生来自第一液体流和第二液体流的乳液产物流，以及微流体乳液 产品导管（205），用于将乳液产品流携带远离接头（204）;（b）流感中的非微流体第一歧管（301） 与所述多个第一微流体导管（202）的连接; 和（c）与所述多个第二微流体导管（203）流体连通的非微流体第二歧管（302）。 其中所述非微流体第一歧管（301）和所述非微流体第二歧管（302）分别与第一可闭合歧管排水（304）和第二可闭合歧管排水（305）流体连通。 还提供了使用上述装置制造乳液产品的方法。

公开(公告)号：WO2007039265A1

公开(公告)日：2007-04-12

申请号：PCT/EP2006/009534

申请日：2006-10-02

Applicant: UNILEVER PLC ,  UNILEVER NV ,  HINDUSTAN LEVER LIMITED ,  BARBIER, Valessa ,  JOUSSE, Fabien, Frederic, Raymond, Marie ,  TABELING, Patrick, Jean, Rene ,  WILLAIME, Hervé

Inventor： BARBIER, Valessa ,  JOUSSE, Fabien, Frederic, Raymond, Marie ,  TABELING, Patrick, Jean, Rene ,  WILLAIME, Hervé

IPC: B01F13/00 ,  B01F5/04 ,  B01F13/10 ,  B01L3/00 ,  B01J19/00

CPC classification number: B01J19/0093 ,  B01F5/0471 ,  B01F13/0059 ,  B01F13/1013 ,  B01F13/1022 ,  B01J2219/00889 ,  B01J2219/00995 ,  Y10T137/2076 ,  Y10T137/212 ,  Y10T137/2224

Abstract: A microfluidic network comprising a plurality of droplet emitters forming droplets of a first fluid in a second fluid immiscible in the first fluid to produce an outlet stream of droplets, wherein each of the emitters are in fluid communication with each other via the network and all have an auto-synchronised droplet formation frequency by hydrodynamic interaction between the emitters is provided. The synchronisation gives a surprisingly narrow droplet size distribution for the network.

Abstract translation: 一种微流体网络，包括多个液滴发射器，其形成在第一流体中不混溶的第二流体中的第一流体的液滴以产生出口液滴流，其中每个发射器经由网络彼此流体连通，并且都具有 提供了通过发射器之间的流体动力学相互作用的自动同步液滴形成频率。 该同步为网络提供了令人惊讶的窄的液滴尺寸分布。

公开(公告)号：WO2005058477A1

公开(公告)日：2005-06-30

申请号：PCT/EP2004/012747

申请日：2004-11-09

Applicant: UNILEVER PLC ,  UNILEVER NV ,  HINDUSTAN LEVER LIMITED ,  JOUSSE, Fabien, Frederic, Raymond, Marie

Inventor： JOUSSE, Fabien, Frederic, Raymond, Marie

IPC: B01J19/00

CPC classification number: B01J19/0093 ,  B01F13/0059 ,  B01F13/1013 ,  B01F13/1022 ,  B01J2219/00783 ,  B01J2219/0086 ,  B01J2219/00889

Abstract: Microfluidic devices that comprise upstream channels that have a resistance higher than the resistance of the down stream channels are robust for blending two fluids, especially if they are oil and water or of different viscosities.

Abstract translation: 包含具有比下游通道的电阻高的电阻的上游通道的微流体装置对于混合两种流体是鲁棒的，特别是如果它们是油和水或不同的粘度。