公开(公告)号：WO2010021717A3

公开(公告)日：2010-04-15

申请号：PCT/US2009004743

申请日：2009-08-20

Applicant: SEQUOIA PHARMACEUTICALS INC ,  EISSENSTAT MICHAEL ,  LU RONGJIAN ,  KANG SANG UK

Inventor： EISSENSTAT MICHAEL ,  LU RONGJIAN ,  KANG SANG UK

IPC: C07D487/14 ,  A61K31/407 ,  A61P31/14 ,  C07K5/08

CPC classification number: C07D487/14 ,  C07K5/0804

Abstract: Novel compounds that are potent inhibitors of hepatitis C virus protease are provided. Pharmaceutical compositions containing one or more of these inhibitors, methods of preparing the inhibitors and methods of using the inhibitors to treat hepatitis C and related disorders also are provided.

Abstract translation: 提供了作为丙型肝炎病毒蛋白酶的有效抑制剂的新型化合物。 还提供了含有这些抑制剂中的一种或多种的药物组合物，制备抑制剂的方法和使用该抑制剂治疗丙型肝炎和相关疾病的方法。

公开(公告)号：WO2010021717A2

公开(公告)日：2010-02-25

申请号：PCT/US2009/004743

申请日：2009-08-20

Applicant: SEQUOIA PHARMACEUTICALS, INC. ,  EISSENSTAT, Michael ,  LU, Rongjian ,  KANG, Sang, Uk

Inventor： EISSENSTAT, Michael ,  LU, Rongjian ,  KANG, Sang, Uk

IPC: C07D471/14 ,  A61K31/395 ,  A61P31/12

CPC classification number: C07D487/14 ,  C07K5/0804

Abstract: Novel compounds that are potent inhibitors of hepatitis C virus protease are provided. Pharmaceutical compositions containing one or more of these inhibitors, methods of preparing the inhibitors and methods of using the inhibitors to treat hepatitis C and related disorders also are provided.

Abstract translation: 提供了作为丙型肝炎病毒蛋白酶的有效抑制剂的新型化合物。 还提供了含有一种或多种这些抑制剂的药物组合物，制备该抑制剂的方法以及使用该抑制剂治疗丙型肝炎和相关病症的方法。