公开(公告)号：WO2006109836A1

公开(公告)日：2006-10-19

申请号：PCT/JP2006/307784

申请日：2006-04-06

Applicant: TEIJIN PHARMA LIMITED ,  TAKEYASU, Takumi ,  SATO, Yoshinori ,  KAWANA, Asahi ,  TAKAHASHI, Yuji ,  ISHIKAWA, Yuji ,  SUDA, Kaoru

Inventor： TAKEYASU, Takumi ,  SATO, Yoshinori ,  KAWANA, Asahi ,  TAKAHASHI, Yuji ,  ISHIKAWA, Yuji ,  SUDA, Kaoru

IPC: C07D403/06

CPC classification number: C07D403/06

Abstract: Two crystal forms of (R)-3-[2-(2-amino-5-trifluoromethoxybenzamido)acetamido]-1-(6-methylindol-3-ylmethyl)pyrrolidine which exhibit specific X-ray powder diffraction patterns or infrared absorption spectra, amorphous form thereof, a pharmaceutical composition containing the crystal or amorphous form as an active ingredient, as well as methods for preparing them are provided.

Abstract translation: 表现出特定X射线粉末衍射图或红外吸收光谱的（R）-3- [2-（2-氨基-5-三氟甲氧基苯甲酰氨基）乙酰氨基] -1-（6-甲基吲哚-3-基甲基）吡咯烷的两种晶型 提供其无定形形式，含有晶体或无定形形式作为活性成分的药物组合物，以及制备它们的方法。