公开(公告)号：WO2003087821A2

公开(公告)日：2003-10-23

申请号：PCT/US2003/010673

申请日：2003-04-07

Applicant: UNIVERSITY OF GEORGIA RESEARCH FOUNDATION ,  KELLY, Lisa S., Ph.D. ,  PUETT, David, J. ,  PIERCE, Michael, J.

Inventor： KELLY, Lisa S., Ph.D. ,  PUETT, David, J. ,  PIERCE, Michael, J.

IPC: G01N33/53

CPC classification number: G01N33/574 ,  A61K47/6811 ,  G01N33/76 ,  G01N2333/42 ,  G01N2333/95 ,  G01N2400/02

Abstract: The present invention details methods to detect glycoproteins in samples to identify a disease state. In particular, an improved sandwich assay is described, using both an antibody and an array of lectins. Methods for increasing the efficiency of interaction of an antibody with a ligand by cleaving the antibody to remove the carbohydrate moiety, and orienting the cleaved fragment on a matrix to enhance recognition of a ligand are also described. Methods of differentiating pregnancy-derived and disease derived samples are also described.

Abstract translation: 本发明详述了检测样品中糖蛋白以识别疾病状态的方法。 特别地，使用抗体和凝集素阵列描述了改进的夹心测定法。 还描述了通过切割抗体以除去碳水化合物部分并且将切割的片段取向于基质以增强配体的识别来提高抗体与配体的相互作用效率的方法。 还描述了区分妊娠衍生和疾病衍生样品的方法。

公开(公告)号：WO2006119512A3

公开(公告)日：2007-11-15

申请号：PCT/US2006017906

申请日：2006-05-05

Applicant: UNIV VIRGINIA ,  PANNUNZIO MICHAEL ,  POELSTRA KORNELIS ,  PEIRCE-COTTLER SHAYN ,  KESSER BRADLEY ,  GAUSE DANIELLE ,  ROY ANURADHA ,  KELLY LISA S

Inventor： PANNUNZIO MICHAEL ,  POELSTRA KORNELIS ,  PEIRCE-COTTLER SHAYN ,  KESSER BRADLEY ,  GAUSE DANIELLE ,  ROY ANURADHA ,  KELLY LISA S

IPC: A61M1/00

CPC classification number: A61F11/002

Abstract: According to some embodiments, a medical device for treatment of Otitis Media includes a housing or body, a hollow tube protruding therefrom, a suction tube extending from the hollow tube and an ear tube located between the distal end of the suction tube and the hollow tube. A vacuum can be provided so as to suction fluid contained in an ear canal and/or middle ear into the suction tube. The ear tube is slideably moveable relative to the suction tube so that it can be disengaged from the device by pushing it beyond the distal end of the suction tube. In some embodiments, a scalpel is also integrated into the medical device. In preferred embodiments, a trigger communicates with a slider assembly which moves the hollow tube when the trigger is actuated, thereby disengaging the ear tube.

Abstract translation: 根据一些实施例，用于治疗中耳炎的医疗装置包括壳体或主体，从其突出的中空管，从中空管延伸的吸管和位于吸管的远端和中空管之间的耳管 。 可以提供真空以将包含在耳道和/或中耳中的流体吸入吸管中。 耳管相对于吸管可滑动地移动，使得它可以通过将其推出超过吸管的远端而从装置脱离。 在一些实施例中，解剖刀也整合到医疗装置中。 在优选实施例中，触发器与当触发器被致动时移动中空管的滑块组件连通，从而使耳管脱离。

公开(公告)号：WO2017052495A1

公开(公告)日：2017-03-30

申请号：PCT/US2015/051224

申请日：2015-09-21

Applicant: FOSTON, Richard, A. ,  KELLY, Lisa, E.

Inventor： FOSTON, Richard, A. ,  KELLY, Lisa, E.

IPC: G06Q20/34

CPC classification number: G06Q20/34 ,  G06Q20/20

Abstract: The invention disclosure relates a method and system that converts routine cash sales transactions into a banking transaction at the point of sale. It provides cash sale purchasers, i.e. consumers, with the option of electronically depositing their change into a savings or other type of account with a financial institution at the point of sale. The account is linked to the consumer's magnetic stripe change card; the magnetic stripe is placed on the automated and transactional magnetic change card.

Abstract translation: 本发明公开涉及一种将常规现金销售交易转换为销售点的银行交易的方法和系统。 它提供现金销售买家，即消费者，可以选择在销售点向金融机构电子存入变更为储蓄或其他类型的账户。 该帐户与消费者的磁条更换卡相关联; 磁条被放置在自动和交易磁性换卡上。

公开(公告)号：WO2006119512A2

公开(公告)日：2006-11-09

申请号：PCT/US2006/017906

申请日：2006-05-05

Applicant: UNIVERSITY OF VIRGINIA PATENT FOUNDATION ,  PANNUNZIO, Michael ,  POELSTRA, Kornelis ,  PEIRCE-COTTLER, Shayn ,  KESSER, Bradley ,  GAUSE, Danielle ,  ROY, Anuradha ,  KELLY, Lisa, S.

Inventor： PANNUNZIO, Michael ,  POELSTRA, Kornelis ,  PEIRCE-COTTLER, Shayn ,  KESSER, Bradley ,  GAUSE, Danielle ,  ROY, Anuradha ,  KELLY, Lisa, S.

IPC: A61M39/00

CPC classification number: A61F11/002

Abstract: According to some embodiments, a medical device for treatment of Otitis Media includes a housing or body, a hollow tube protruding therefrom, a suction tube extending from the hollow tube and an ear tube located between the distal end of the suction tube and the hollow tube. A vacuum can be provided so as to suction fluid contained in an ear canal and/or middle ear into the suction tube. The ear tube is slideably moveable relative to the suction tube so that it can be disengaged from the device by pushing it beyond the distal end of the suction tube. In some embodiments, a scalpel is also integrated into the medical device. In preferred embodiments, a trigger communicates with a slider assembly which moves the hollow tube when the trigger is actuated, thereby disengaging the ear tube.

Abstract translation: 根据一些实施例，用于治疗中耳炎的医疗装置包括壳体或主体，从其突出的中空管，从中空管延伸的吸管和位于吸管的远端和中空管之间的耳管 。 可以提供真空以将包含在耳道和/或中耳中的流体吸入吸管中。 耳管相对于吸管可滑动地移动，使得它可以通过将其推出超过吸管的远端而从装置脱离。 在一些实施例中，解剖刀也整合到医疗装置中。 在优选实施例中，触发器与当触发器被致动时移动中空管的滑块组件连通，从而使耳管脱开。

公开(公告)号：WO2021086329A1

公开(公告)日：2021-05-06

申请号：PCT/US2019/058542

申请日：2019-10-29

Applicant: WACKER CHEMIE AG ,  KELLY, Lisa

Inventor： RUDOLPH, Timothy

IPC: C08L21/02

Abstract: Pigmented latex compositions having a solids content in the range from 60 wt % to 95 wt % comprise a vinyl acetate ethylene copolymer dispersion (VAE dispersion) and one or more plasticizers from the group of polyethylene glycol diesters of polyethylene glycols having 3 to 10 ethylene glycol units with C1-C10 alkyl carboxylic acids wherein the carboxylic acids are identical or different and are branched or unbranched alkyl carboxylic acids. The high solids pigmented latex compositions are particularly useful for the preparation of mastic and caulk compositions.

公开(公告)号：WO2003087821A3

公开(公告)日：2003-10-23

申请号：PCT/US2003/010673

申请日：2003-04-07

Applicant: UNIVERSITY OF GEORGIA RESEARCH FOUNDATION ,  KELLY, Lisa S., Ph.D. ,  PUETT, David, J. ,  PIERCE, Michael, J.

Inventor： KELLY, Lisa S., Ph.D. ,  PUETT, David, J. ,  PIERCE, Michael, J.

IPC: G01N33/53

Abstract: The present invention details methods to detect glycoproteins in samples to identify a disease state. In particular, an improved sandwich assay is described, using both an antibody and an array of lectins. Methods for increasing the efficiency of interaction of an antibody with a ligand by cleaving the antibody to remove the carbohydrate moiety, and orienting the cleaved fragment on a matrix to enhance recognition of a ligand are also described. Methods of differentiating pregnancy-derived and disease derived samples are also described.