Abstract:
There is provided a gene transfer vehicle comprising first and second site specific recombinase sites and at least one gene of interest located therebetween. The first and second site specific recombinase sites cannot recombine together. Optionally the vehicle encodes a recombinase enzyme. The gene transfer vehicle can be a viral vector, for example based on an adenovirus or retrovirus.The vehicle allows highly targeted insertion of a transgene enabling efficient insertion and expression.
Abstract:
There is provided a gene transfer vehicle comprising first and second site specific recombinase sites and at least one gene of interest located therebetween. The first and second site specific recombinase sites cannot recombine together. Optionally the vehicle encodes a recombinase enzyme. The gene transfer vehicle can be a viral vector, for example based on an adenovirus or retrovirus.The vehicle allows highly targeted insertion of a transgene enabling efficient insertion and expression.
Abstract:
Die Erfindung betrifft eine Belüftungseinrichtung (1) für mit Hydraulikflüssigkeit befüllbare, von geschlossenen Hydrauliksystemen umfasste Tankbehälter (2), insbesondere in Nutzfahrzeugen, beinhaltend wenigstens eine einen Be- und Entlüftungsweg begrenzende, gasdurchlässige aber im wesentlichen flüssigkeitsundurchlässige Membran (34). Die Erfindung sieht vor, dass die Membran (34) wenigstens zwei Schichten (54, 56), jeweils aus einem Polyamidgewebe und/oder einem Polyestergewebe bestehend, umfasst, wobei eine dickere Schicht (54) zu einem Innenraum (10) des Tankbehälters (2) und eine dünnere Schicht (56) von diesem Innenraum (10) weg weist, die Dicke einer Schicht (54, 56) in einem Bereich zwischen 30 und 400 μm liegt.
Abstract:
In a safety belt for a vehicle occupant restraint system which replaces conventional force limiting devices, which involve additional structural measures and costs and may be incorrectly fitted, the warp threads (7) have different lengths per unit length of the belt, i.e. short warp threads (10) which absorb the tractive force arising during an initial extension of the belt (1) without loading the longer warp threads (20), and longer warp threads (20), which take part in absorbing the tractive force acting on the belt (1) after its initial extension depending on the ratio between their length and that of the short warp threads (10).