公开(公告)号：WO2009126227A2

公开(公告)日：2009-10-15

申请号：PCT/US2009/002098

申请日：2009-04-03

Applicant: WILLIAM COOK EUROPE APS ,  COOK INCORPORATED ,  KOLBEL, Tilo ,  MALINA, Martin ,  JENSEN, Kim, Moegelvang ,  OHLENSCHLAEGER, Bent ,  RASMUSSEN, Erik, E.

Inventor： KOLBEL, Tilo ,  MALINA, Martin ,  JENSEN, Kim, Moegelvang ,  OHLENSCHLAEGER, Bent ,  RASMUSSEN, Erik, E.

IPC: A61F2/06 ,  A61F2/84

CPC classification number: A61F2/07 ,  A61F2/89 ,  A61F2/95 ,  A61F2002/075 ,  A61F2002/9511 ,  A61F2002/9517

Abstract: A stent-graft (100) is provided with a tightenable loop element (104) having a first end terminated in a slip knot or self-tightening knot (112) and a second end which is received in and can slide in the knot (112). The knot (112) is tied by a suture to the stent-graft (100) so as to be fixed thereto. The loop (104) is fitted to the stent-graft (100) in a manner as to pass between the inside to the outside of the graft material and in such a manner that controlled curvature of the stent-graft (100) is possible, in particular control of the overlapping of adjacent stents held within the zone of the loop (104). An introducer assembly is also disclosed which includes a control cannula (120) able to the fixed to the stent-graft (100) during the deployment procedure, as well as a mechanism of suture loops (150, 152) at the proximal end of the stent-graft (100) for retaining this in a constricted form during the process of curving the latter during the deployment process.

Abstract translation: 支架移植物（100）设置有可收紧的环形元件（104），其具有终止于滑结或自紧结（112）的第一端，以及容纳在结中并可在结中滑动的第二端（112） ）。 结（112）通过缝合线绑定到支架移植物（100）上，以便固定在其上。 将环（104）以能够在移植物材料的内部到外部之间通过的方式以可能的支架移植物（100）的受控曲率的方式装配到支架移植物（100） 特别是控制保持在环（104）的区域内的相邻支架的重叠。 还公开了一种导引器组件，其包括能够在展开过程期间固定到支架移植物（100）的控制套管（120），以及在该近端处的缝线环（150,152）的机构 支架移植物（100），用于在展开过程中使其在弯曲过程中将其保持在收缩形式中。

公开(公告)号：WO2017025800A1

公开(公告)日：2017-02-16

申请号：PCT/IB2016/001237

申请日：2016-08-11

Applicant: KOLBEL, Tilo

Inventor： KOLBEL, Tilo

IPC: A61F2/95 ,  A61M5/36

CPC classification number: A61F2/95 ,  A61B90/70 ,  A61M5/36

Abstract: Systems and methods are provided for removing air from a medical device, such as a stent-graft and/or its delivery device. In an exemplary embodiment, the stent-graft or its delivery system or both are exposed to perfluorocarbon, by immersing the stent-graft or flushing the delivery device to remove air from the stent-graft. Optionally, the stent-graft and/or delivery system may be flushed multiple times, e.g., with perfluorocarbon before or after flushing with carbon dioxide, saline, a bio-inert gas, and the like. Thereafter, the stent-graft may be introduced into a patient's body and deployed at a target location, such as the site of an abdominal aortic aneurysm.

Abstract translation: 提供了用于从诸如支架移植物和/或其递送装置的医疗装置去除空气的系统和方法。 在一个示例性实施例中，通过浸入支架移植物或冲洗输送装置以从支架移植物中除去空气，将支架移植物或其递送系统或两者暴露于全氟化碳。 任选地，在用二氧化碳，盐水，生物惰性气体等冲洗之前或之后，可以将覆膜 - 移植物和/或递送系统多次冲洗，例如全氟化碳。 此后，将支架移植物引入患者的身体并展开在目标位置，例如腹主动脉瘤的部位。

公开(公告)号：WO2010062355A1

公开(公告)日：2010-06-03

申请号：PCT/US2009/005890

申请日：2009-10-30

Applicant: WILLIAM COOK EUROPE APS ,  COOK INCORPORATED ,  KOLBEL, Tilo ,  RASMUSSEN, Erik, E. ,  OHLENSCHLAEGER, Bent ,  JENSEN, Kim, Moegelvang

Inventor： KOLBEL, Tilo ,  RASMUSSEN, Erik, E. ,  OHLENSCHLAEGER, Bent ,  JENSEN, Kim, Moegelvang

IPC: A61F2/06 ,  A61F2/84

CPC classification number: A61F2/07 ,  A61F2/89 ,  A61F2/95 ,  A61F2002/9505 ,  A61F2002/9511 ,  A61F2002/9517 ,  A61F2230/0067

Abstract: A stent graft (18) for deployment in a curved lumen such as the aortic or thoracic arch (130) comprises a constraining mechanism at its proximal end. A stent (4') provided at the proximal end of the stent graft (18) includes loops of material (11) that co-operate with restraining wires (42) that extend between a central guide wire carrier (24) and a restraining wire cannula (8). The constraining mechanism acts to maintain the proximal stent (4') constrained at three points around its circumference at both the proximal and distal ends of the proximal stent (41). The proximal stent (41) is thus allowed to expand after expansion of the remainder of the stent graft (18) during deployment. In an embodiment, the constraining mechanism acts to constrain two adjacent struts of the proximal stent (4') at three points radially therearound, at the proximal end of the stent (41) and at the distal end of the stent (41). The proximal stent (4') may then overlap with the interior of an adjacent stent at an inner part (31) of a curved vessel.

Abstract translation: 用于展开在诸如主动脉或胸廓弓（130）的弯曲内腔中的支架移植物（18）在其近端处包括约束机构。 设置在支架移植物（18）的近端处的支架（4'）包括与限制线（42）配合的材料环（11），所述限制线（42）在中心导丝架（24）和限制线 套管（8）。 约束机构用于将近端支架（4'）保持在近端支架（41）的近端和远端处围绕其圆周的三个点处受限。 因此，在展开期间，近端支架（41）能够在扩张支架移植物（18）的其余部分之后膨胀。 在一个实施例中，约束机构用于约束近端支架（4'）的两个相邻的支柱，其位于其周围的径向周围的三个点处，在支架（41）的近端处以及支架（41）的远端处。 近端支架（4'）然后可以在弯曲容器的内部部分（31）处与相邻支架的内部重叠。

公开(公告)号：WO2017072592A1

公开(公告)日：2017-05-04

申请号：PCT/IB2016/001908

申请日：2016-10-28

Applicant: KOLBEL, Tilo

Inventor： KOLBEL, Tilo

IPC: A61F2/95 ,  A61F2/962 ,  A61B90/70

CPC classification number: A61B90/70 ,  A61B2090/701 ,  A61F2/82 ,  A61F2/95 ,  A61F2/962 ,  B08B9/0328

Abstract: Systems and methods are provided for degassing a medical device. In one embodiment, a flushing device is provided that includes a tubular member including first and second ends and a chamber therein. First and second ports are spaced apart from one another along the tubular member and communicate with the chamber. One or more sources of flushing fluid are connectable to the first and/or second ports to create a flushing circuit, e.g., delivering flushing fluid into the first port, through the chamber, and out the second port to remove air or other gases from the chamber. An introducing assembly carrying a stent-graft may be introduced into the chamber, flushed, and then transferred to a delivery device. Thereafter, the stent-graft may be introduced into a patient's body and deployed at a target location, such as the site of an abdominal aortic aneurysm.

Abstract translation: 系统和方法被提供用于使医疗装置脱气。 在一个实施例中，提供了一种冲洗装置，其包括管状构件，该管状构件包括第一端和第二端以及其中的腔室。 第一端口和第二端口沿着管状构件彼此间隔开并且与腔室连通。 一个或多个冲洗流体源可连接到第一和/或第二端口以形成冲洗回路，例如，将冲洗流体输送到第一端口中，通过腔室并从第二端口输出，以从第一端口移除空气或其他气体 室。 携带支架移植物的引入组件可以被引入室中，冲洗，然后转移到递送装置。 此后，可以将支架移植物引入患者体内并展开在目标位置，例如腹主动脉瘤部位。

公开(公告)号：WO2009126227A3

公开(公告)日：2009-12-10

申请号：PCT/US2009002098

申请日：2009-04-03

Applicant: COOK WILLIAM EUROP ,  COOK INC ,  KOLBEL TILO ,  MALINA MARTIN ,  JENSEN KIM MOEGELVANG ,  OHLENSCHLAEGER BENT ,  RASMUSSEN ERIK E

Inventor： KOLBEL TILO ,  MALINA MARTIN ,  JENSEN KIM MOEGELVANG ,  OHLENSCHLAEGER BENT ,  RASMUSSEN ERIK E

IPC: A61F2/06 ,  A61F2/84

CPC classification number: A61F2/07 ,  A61F2/89 ,  A61F2/95 ,  A61F2002/075 ,  A61F2002/9511 ,  A61F2002/9517

Abstract: A stent-graft (100) is provided with a tightenable loop element (104) having a first end terminated in a slip knot or self-tightening knot (112) and a second end which is received in and can slide in the knot (112). The knot (112) is tied by a suture to the stent-graft (100) so as to be fixed thereto. The loop (104) is fitted to the stent-graft (100) in a manner as to pass between the inside to the outside of the graft material and in such a manner that controlled curvature of the stent-graft (100) is possible, in particular control of the overlapping of adjacent stents held within the zone of the loop (104). An introducer assembly is also disclosed which includes a control cannula (120) able to the fixed to the stent-graft (100) during the deployment procedure, as well as a mechanism of suture loops (150, 152) at the proximal end of the stent-graft (100) for retaining this in a constricted form during the process of curving the latter during the deployment process.

Abstract translation: 支架移植物（100）设置有可收紧的环形元件（104），该可收紧的环形元件具有以滑结或自紧结（112）终止的第一端和容纳并且可以在结（112 ）。 结（112）通过缝合线系到支架移植物（100）上以固定在其上。 环（104）以在移植物材料的内部到外部之间穿过的方式安装到支架移植物（100），并且以这样的方式使得支架移植物（100）的受控曲率成为可能， 特别是控制保持在环路（104）的区域内的相邻支架的重叠。 还公开了一种导引器组件，其包括能够在展开过程期间固定到支架 - 移植物（100）的控制套管（120），以及位于支架移植物（100）近端处的缝合线环（150,152） 覆膜支架（100），用于在展开过程中使后者弯曲的过程中将其保持为收缩形式。