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    STENT-GRAFT AND APPARATUS AND FITTING METHOD
    1.
    发明申请
    STENT-GRAFT AND APPARATUS AND FITTING METHOD 审中-公开

    公开(公告)号：WO2009126227A2

    公开(公告)日：2009-10-15

    申请号：PCT/US2009/002098

    申请日：2009-04-03

    Applicant: WILLIAM COOK EUROPE APS ,  COOK INCORPORATED ,  KOLBEL, Tilo ,  MALINA, Martin ,  JENSEN, Kim, Moegelvang ,  OHLENSCHLAEGER, Bent ,  RASMUSSEN, Erik, E.

    Inventor： KOLBEL, Tilo ,  MALINA, Martin ,  JENSEN, Kim, Moegelvang ,  OHLENSCHLAEGER, Bent ,  RASMUSSEN, Erik, E.

    IPC: A61F2/06 ,  A61F2/84

    CPC classification number: A61F2/07 ,  A61F2/89 ,  A61F2/95 ,  A61F2002/075 ,  A61F2002/9511 ,  A61F2002/9517

    Abstract: A stent-graft (100) is provided with a tightenable loop element (104) having a first end terminated in a slip knot or self-tightening knot (112) and a second end which is received in and can slide in the knot (112). The knot (112) is tied by a suture to the stent-graft (100) so as to be fixed thereto. The loop (104) is fitted to the stent-graft (100) in a manner as to pass between the inside to the outside of the graft material and in such a manner that controlled curvature of the stent-graft (100) is possible, in particular control of the overlapping of adjacent stents held within the zone of the loop (104). An introducer assembly is also disclosed which includes a control cannula (120) able to the fixed to the stent-graft (100) during the deployment procedure, as well as a mechanism of suture loops (150, 152) at the proximal end of the stent-graft (100) for retaining this in a constricted form during the process of curving the latter during the deployment process.

    Abstract translation: 支架移植物（100）设置有可收紧的环形元件（104），其具有终止于滑结或自紧结（112）的第一端，以及容纳在结中并可在结中滑动的第二端（112） ）。 结（112）通过缝合线绑定到支架移植物（100）上，以便固定在其上。 将环（104）以能够在移植物材料的内部到外部之间通过的方式以可能的支架移植物（100）的受控曲率的方式装配到支架移植物（100） 特别是控制保持在环（104）的区域内的相邻支架的重叠。 还公开了一种导引器组件，其包括能够在展开过程期间固定到支架移植物（100）的控制套管（120），以及在该近端处的缝线环（150,152）的机构 支架移植物（100），用于在展开过程中使其在弯曲过程中将其保持在收缩形式中。

    IMPLANTABLE MEDICAL DEVICE
    2.
    发明申请
    IMPLANTABLE MEDICAL DEVICE 审中-公开
    可植入医疗器械

    公开(公告)号：WO2011019546A1

    公开(公告)日：2011-02-17

    申请号：PCT/US2010/044244

    申请日：2010-08-03

    Applicant: WILLIAM COOK EUROPE APS ,  COOK INCORPORATED ,  RASMUSSEN, Erik ,  OEHLENSCHLAEGER, Bent ,  JENSEN, Kim, Moegelvang ,  PETERSEN, Jesper, Schade

    Inventor： RASMUSSEN, Erik ,  OEHLENSCHLAEGER, Bent ,  JENSEN, Kim, Moegelvang ,  PETERSEN, Jesper, Schade

    IPC: A61F2/06

    CPC classification number: A61F2/07 ,  A61F2/844 ,  A61F2/86 ,  A61F2/89 ,  A61F2/90 ,  A61F2002/075 ,  A61F2002/8483 ,  A61F2210/0014 ,  A61F2220/0058 ,  A61F2220/0075 ,  A61F2310/00023

    Abstract: A stent graft (10) includes a tubular graft element (12) to which there are attached a plurality of stent rings (14). The stent rings (14) are formed of a plurality of stent struts (16) arranged in a zig-zag arrangement with alternating peaks (18) and valleys (20). The end-most stent (22) is located at the proximal end (24) of the graft tube (12). Between adjacent peaks (18) of the end-most stent (22), there is provided a series of bridging elements (28). These are preferably formed of Nitinol wire and to be substantially more flexible than the stent struts (14). The bridging elements (28) extend in the region of graft material between adjacent stent peaks (18) and are attached to the graft material, for example by suturing. The bridging elements (28) are substantially more flexible than the stent ring (22) and therefore impart little opening force on the graft material in comparison to the force produced by the stent ring (22). However, the bridging elements (28) impart enough force on the flaps (26) of graft material between the peaks (18) of the stent ring (28) keep these flaps (26) open, that is against the vessel wall. The bridging elements (28) can provide integral barbs (30).

    Abstract translation: 支架移植物（10）包括管状移植物元件（12），其上附接有多个支架环（14）。 支架环（14）由布置成具有交替的峰（18）和谷（20）的之字形布置的多个支架支柱（16）形成。 最终的支架（22）位于移植管（12）的近端（24）处。 在最终支架（22）的相邻峰（18）之间，提供一系列桥接元件（28）。 这些优选由镍钛诺丝形成，并且比支架支柱（14）基本上更具柔性。 桥接元件（28）在相邻支架顶部（18）之间的移植材料区域中延伸并且例如通过缝合附接到移植物材料。 桥接元件（28）比支架环（22）大得多的柔性，因此与支架环（22）产生的力相比，在接枝材料上施加很小的打开力。 然而，桥接元件（28）在支架环（28）的峰（18）之间的移植材料的翼片（26）上赋予足够的力，使得这些翼片（26）打开，即抵靠血管壁。 桥接元件（28）可以提供整体倒钩（30）。

    INTRODUCER FOR DEPLOYING A STENT GRAFT IN A CURVED LUMEN AND STENT GRAFT THEREFOR
    4.
    发明申请
    INTRODUCER FOR DEPLOYING A STENT GRAFT IN A CURVED LUMEN AND STENT GRAFT THEREFOR 审中-公开
    用于在弯曲的乳汁和其中的植入物中施加一个椎间盘的介绍

    公开(公告)号：WO2010062355A1

    公开(公告)日：2010-06-03

    申请号：PCT/US2009/005890

    申请日：2009-10-30

    Applicant: WILLIAM COOK EUROPE APS ,  COOK INCORPORATED ,  KOLBEL, Tilo ,  RASMUSSEN, Erik, E. ,  OHLENSCHLAEGER, Bent ,  JENSEN, Kim, Moegelvang

    Inventor： KOLBEL, Tilo ,  RASMUSSEN, Erik, E. ,  OHLENSCHLAEGER, Bent ,  JENSEN, Kim, Moegelvang

    IPC: A61F2/06 ,  A61F2/84

    CPC classification number: A61F2/07 ,  A61F2/89 ,  A61F2/95 ,  A61F2002/9505 ,  A61F2002/9511 ,  A61F2002/9517 ,  A61F2230/0067

    Abstract: A stent graft (18) for deployment in a curved lumen such as the aortic or thoracic arch (130) comprises a constraining mechanism at its proximal end. A stent (4') provided at the proximal end of the stent graft (18) includes loops of material (11) that co-operate with restraining wires (42) that extend between a central guide wire carrier (24) and a restraining wire cannula (8). The constraining mechanism acts to maintain the proximal stent (4') constrained at three points around its circumference at both the proximal and distal ends of the proximal stent (41). The proximal stent (41) is thus allowed to expand after expansion of the remainder of the stent graft (18) during deployment. In an embodiment, the constraining mechanism acts to constrain two adjacent struts of the proximal stent (4') at three points radially therearound, at the proximal end of the stent (41) and at the distal end of the stent (41). The proximal stent (4') may then overlap with the interior of an adjacent stent at an inner part (31) of a curved vessel.

    Abstract translation: 用于展开在诸如主动脉或胸廓弓（130）的弯曲内腔中的支架移植物（18）在其近端处包括约束机构。 设置在支架移植物（18）的近端处的支架（4'）包括与限制线（42）配合的材料环（11），所述限制线（42）在中心导丝架（24）和限制线 套管（8）。 约束机构用于将近端支架（4'）保持在近端支架（41）的近端和远端处围绕其圆周的三个点处受限。 因此，在展开期间，近端支架（41）能够在扩张支架移植物（18）的其余部分之后膨胀。 在一个实施例中，约束机构用于约束近端支架（4'）的两个相邻的支柱，其位于其周围的径向周围的三个点处，在支架（41）的近端处以及支架（41）的远端处。 近端支架（4'）然后可以在弯曲容器的内部部分（31）处与相邻支架的内部重叠。

    APPARATUS FOR CURVING AN IMPLANTABLE MEDICAL DEVICE IN A LUMEN
    5.
    发明申请
    APPARATUS FOR CURVING AN IMPLANTABLE MEDICAL DEVICE IN A LUMEN 审中-公开
    用于在LUMEN中弯曲可植入医疗装置的装置

    公开(公告)号：WO2010042210A1

    公开(公告)日：2010-04-15

    申请号：PCT/US2009/005545

    申请日：2009-10-09

    Applicant: WILLIAM COOK EUROPE APS ,  COOK INCORPORATED ,  RASMUSSEN, Erik, E. ,  OEHLENSCHLAEGER, Bent ,  JENSEN, Kim, Moegelvang

    Inventor： RASMUSSEN, Erik, E. ,  OEHLENSCHLAEGER, Bent ,  JENSEN, Kim, Moegelvang

    IPC: A61F2/84

    CPC classification number: A61F2/95 ,  A61F2002/9505 ,  A61F2002/9511 ,  A61F2002/9517

    Abstract: An introducer assembly (100) including at its distal end a dilator tip (20) and an inner catheter for supporting an implantable medical device (1) for deployment, is provided with a plurality of strut elements (102, 202) extending from the dilator tip (20) to the proximal end of the medical device (1 ). The strut elements (102, 202) act to apply both a pulling and a pushing force against the proximal end of the medical device (1), having the effect of assisting in the correct positioning of the proximal end of the medical device in a patient's lumen, particularly where this is curved such as with the aortic arch. The strut elements (102, 202) form part of the introducer assembly and are removed from the patient following the deployment procedure. The device avoids the need for bare stents at the end of a stent graft.

    Abstract translation: 导引器组件（100）在其远端包括扩张器尖端（20）和用于支撑用于展开的可植入医疗装置（1）的内导管，其具有从扩张器延伸的多个支柱元件（102,202） 尖端（20）到医疗装置（1）的近端。 支撑元件（102,202）用于将拉力和推力施加到医疗装置（1）的近端上，其作用是帮助将医疗装置的近端正确定位在患者体内 特别是在弯曲的地方，如主动脉弓。 支撑元件（102,202）形成导引器组件的一部分，并且在部署过程之后从患者身上移除。 该装置避免了在支架移植物末端需要裸支架。

    STENT MEMBER
    7.
    发明申请
    STENT MEMBER 审中-公开

    公开(公告)号：WO2010053563A1

    公开(公告)日：2010-05-14

    申请号：PCT/US2009005997

    申请日：2009-11-06

    Applicant: COOK WILLIAM EUROP ,  COOK INC ,  RASMUSSEN ERIK ,  JENSEN KIM MOEGELVANG

    Inventor： RASMUSSEN ERIK ,  JENSEN KIM MOEGELVANG

    IPC: A61F2/07 ,  A61F2/82 ,  A61F2/89 ,  A61F2/91

    CPC classification number: A61F2/91 ,  A61F2/07 ,  A61F2/89 ,  A61F2002/075 ,  A61F2002/826 ,  A61F2220/0016

    Abstract: A rotationally-symmetric stent graft (10; 30) for deploying in a curved vessel (32) has identical spaced stents (16) along its length, with the stents being further apart in the region of the greatest curvature. The ends of the stents are parallel to each other and to the ends of the graft. The inter-stent spacing (D) may vary along the entire length of the graft or only adjacent one end.

    Abstract translation: 用于在弯曲的血管（32）中展开的旋转对称的支架移植物（10; 30）沿其长度具有相同的间隔开的支架（16），支架在最大曲率的区域中进一步分开。 支架的末端彼此平行并且与移植物的末端平行。 支架间距（D）可以沿着移植物的整个长度或仅在相邻的一个端部上变化。

    STENT-GRAFT AND APPARATUS AND FITTING METHOD
    8.
    发明申请
    STENT-GRAFT AND APPARATUS AND FITTING METHOD 审中-公开
    支架和装置及配件方法

    公开(公告)号：WO2009126227A3

    公开(公告)日：2009-12-10

    申请号：PCT/US2009002098

    申请日：2009-04-03

    Applicant: COOK WILLIAM EUROP ,  COOK INC ,  KOLBEL TILO ,  MALINA MARTIN ,  JENSEN KIM MOEGELVANG ,  OHLENSCHLAEGER BENT ,  RASMUSSEN ERIK E

    Inventor： KOLBEL TILO ,  MALINA MARTIN ,  JENSEN KIM MOEGELVANG ,  OHLENSCHLAEGER BENT ,  RASMUSSEN ERIK E

    IPC: A61F2/06 ,  A61F2/84

    CPC classification number: A61F2/07 ,  A61F2/89 ,  A61F2/95 ,  A61F2002/075 ,  A61F2002/9511 ,  A61F2002/9517

    Abstract: A stent-graft (100) is provided with a tightenable loop element (104) having a first end terminated in a slip knot or self-tightening knot (112) and a second end which is received in and can slide in the knot (112). The knot (112) is tied by a suture to the stent-graft (100) so as to be fixed thereto. The loop (104) is fitted to the stent-graft (100) in a manner as to pass between the inside to the outside of the graft material and in such a manner that controlled curvature of the stent-graft (100) is possible, in particular control of the overlapping of adjacent stents held within the zone of the loop (104). An introducer assembly is also disclosed which includes a control cannula (120) able to the fixed to the stent-graft (100) during the deployment procedure, as well as a mechanism of suture loops (150, 152) at the proximal end of the stent-graft (100) for retaining this in a constricted form during the process of curving the latter during the deployment process.

    Abstract translation: 支架移植物（100）设置有可收紧的环形元件（104），该可收紧的环形元件具有以滑结或自紧结（112）终止的第一端和容纳并且可以在结（112 ）。 结（112）通过缝合线系到支架移植物（100）上以固定在其上。 环（104）以在移植物材料的内部到外部之间穿过的方式安装到支架移植物（100），并且以这样的方式使得支架移植物（100）的受控曲率成为可能， 特别是控制保持在环路（104）的区域内的相邻支架的重叠。 还公开了一种导引器组件，其包括能够在展开过程期间固定到支架 - 移植物（100）的控制套管（120），以及位于支架移植物（100）近端处的缝合线环（150,152） 覆膜支架（100），用于在展开过程中使后者弯曲的过程中将其保持为收缩形式。

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