Abstract:
A gene that is a positive mediator of tumor growth and metastasis in certain cancer types is provided. This gene and corresponding polypeptide have diagnostic and therapeutic application for detecting and treating cancers that involve expression of SCC-S2 such as renal, ovarian, head and neck, breast, prostate, brain, chronic myelogenous leukemia, lung, lymphoblastic leukemia, and colorectal adenocarcinoma cells.
Abstract:
A gene that is a modulator of tumor growth and metastasis in certain cancer type is provided. SCC-112 (about 150 kDa) and/or a mutant form of SCC-112 (about 65 kDa) is a tumor suppressor molecule. This gene and corresponding polypeptide have diagnostic and therapeutic application for detecting and treating cancers that involve expression of SCC-112 such as breast and kidney cancers.
Abstract:
A gene that is a modulator of tumor growth and metastasis in certain cancer types is provided. This gene and corresponding polypeptide have diagnostic and therapeutic application for detecting and treating cancers that involve expression of BRCC2 such as breast cancer and lung cancer.
Abstract:
A gene that is a positive mediator of tumor growth and metastasis in certain cancer types is provided. This gene and corresponding polypeptide have diagnostic and therapeutic application for detecting and treating cancers that involve expression of SCC-S2 such as renal, ovarian, head and neck, breast, prostate, brain, chronic myelogenous leukemia, lung, lymphoblastic leukemia, and colorectal adenocarcinoma cells.
Abstract:
A bone fracture fixation plate juxta-articular stabilisation means comprises a plate with integral pin and tail parts, a plate specific jig, a plate and jig specific drill sleeve, a slotted head top loading screw, a plate positioner and a pin bender. This system can be used for fixation of most types of fractures involving the juxta-articular radius. The plate has a most juxta-articular row of screw holes in individually bendable and detachable extensions especially designed for very juxta-articular or the volar lip fractures. The plate also has bendable and detachable pin part and tail parts on either ends that allows the plate to be used with a chuck as a wire or drill bit and also have longer purchase into the bone with minimal soft tissue exposure. The plate and targeting assembly have plate positioning slots for wires in its juxta-articular part to allow adjustment in position of plate in longitudinal, transverse and oblique directions after initial fixation with wires without committing to a screw hole. This allows a very precise placement of the plate in the most ideal position. The targeting assembly can be mounted onto the plate prior to surgery thus reducing surgical step and time. The specific orientation of the screw holes in the shaft part of the plate orientates the screws such that when tendons apply forces across the fracture, the plate is wedged between screw and the bone rather than pushed away from the bone. Therefore, more aggressive physical therapy can be commenced earlier or plates with fewer screws in the proximal part can be used without compromising the strength of the fixation.
Abstract:
A gene that is a modulator of tumor growth and metastasis in certain cancer type is provided. SCC-112 (about 150 kDa) and/or a mutant form of SCC-112 (about 65 kDa) is a tumor suppressor molecule. This gene and corresponding polypeptide have diagnostic and therapeutic application for detecting and treating cancers that involve expression of SCC-112 such as breast and kidney cancers.
Abstract:
A gene that is a modulator of tumor growth and metastasis in certain cancer types is provided. This gene and corresponding polypeptide have diagnostic and therapeutic application for detecting and treating cancers that involve expression of BRCC2 such as breast cancer and lung cancer.
Abstract:
A switching network includes an upper tier including a master switch and a lower tier including a plurality of lower tier entities. The master switch includes a plurality of ports each coupled to a respective one of the plurality of lower tier entities. Each of the plurality of ports includes a plurality of virtual ports each corresponding to a respective one of a plurality of remote physical interfaces (RPIs) at the lower tier entity coupled to that port. Each of the plurality of ports also includes a receive interface that, responsive to receipt of data traffic from a particular lower tier entity among the plurality of lower tier entities, queues the data traffic to the virtual port among the plurality of virtual ports that corresponds to the RPI on the particular lower tier entity that was the source of the data traffic. The master switch further includes a switch controller that switches data traffic from the virtual port to an egress port among the plurality of ports from which the data traffic is forwarded.
Abstract:
The invention discloses an improved vertical tube falling film heat exchanger wherein the improvement comprises of a simple but novel tube extension (3) of a substantially inverted funnel shaped configuration at the upper ends of the vertical tubes (2), whereby the said extension (3) permits the use of honeycomb calandria in the vertical tube falling film heat exchangers by ensuring uniform liquid distribution in the vertical tubes (2) and completely eliminates the need of a separate distribution means interposed between superimposed banks of vertical tubes.
Abstract:
A gene that is a modulator of tumor growth and metastasis in certain cancer types is provided. This gene and corresponding polypeptide have diagnostic and therapeutic application for detecting and treating cancers that involve expression of BRCC-3 such as breast cancer and lung cancer.