公开(公告)号：WO2010119454A1

公开(公告)日：2010-10-21

申请号：PCT/IN2010/000241

申请日：2010-04-15

Applicant: WIPRO LIMITED ,  KUMAR, Vipul

Inventor： KUMAR, Vipul

IPC: A47B96/06 ,  A47B96/07 ,  F16B12/32 ,  F16B12/50

CPC classification number: F16B12/32 ,  A47B91/00 ,  A47B2200/0013 ,  A47B2200/08 ,  F16B7/025 ,  F16B12/02 ,  F16B12/50 ,  F16B37/045

Abstract: The disclosure relates to a furniture system, more particularly related to locking mechanism comprising a beam, wedge nut and bracket. The beam in the locking mechanism forms the main spine of modular office furniture system and allows for easy connectivity of legs & posts at any point on the beam rendering it to be very flexible for configuration/reconfiguration.

Abstract translation: 本公开涉及一种家具系统，更具体地涉及包括梁，楔形螺母和支架的锁定机构。 锁定机构中的梁形成模块化办公家具系统的主要脊柱，并允许在梁上的任何点处轻松连接腿和柱，使其对于配置/重新配置非常灵活。

公开(公告)号：WO2010134096A2

公开(公告)日：2010-11-25

申请号：PCT/IN2010/000322

申请日：2010-05-19

Applicant: PREMAS BIOTECH PVT. LTD ,  SONI, Rajeev ,  KUNDU, Prabuddha Kumar ,  ARORA, Kajal ,  RAO, Purna Chandra ,  BHALLA, Kunal ,  SUMAN, Sunil Kumar ,  KUMAR, Vipul

Inventor： SONI, Rajeev ,  KUNDU, Prabuddha Kumar ,  ARORA, Kajal ,  RAO, Purna Chandra ,  BHALLA, Kunal ,  SUMAN, Sunil Kumar ,  KUMAR, Vipul

IPC: C07K14/80

CPC classification number: C12N9/0071 ,  C12N15/81 ,  C12Q1/26 ,  C12Y114/14001 ,  G01N2333/90209

Abstract: The present invention provides modified polynucleotide sequences coding for human cytochrome P450 reductase, human cytochrome P450 and human cytochrome b5. Further a genetically modified protease deficient yeast strain comprising integrated modified human cytochrome P450 reductase gene is provided in the present invention. The present invention also provides a genetically modified protease deficient yeast strain comprising integrated modified human cytochrome P450 reductase gene and a plasmid comprising modified polynucleotide sequence coding for cytochrome P450s and/or modified polynucleotide sequence coding for cytochrome b5. The yeast strain(s) disclosed in the present invention have been shown to express catalytically active cytochrome P450s with higher specific activity

Abstract translation: 本发明提供了编码人细胞色素P450还原酶，人细胞色素P450和人细胞色素b5的修饰的多核苷酸序列。 此外，在本发明中提供了包含整合的修饰的人细胞色素P450还原酶基因的遗传修饰的蛋白酶缺陷型酵母菌株。 本发明还提供了包含整合的修饰的人细胞色素P450还原酶基因的遗传修饰的蛋白酶缺陷型酵母菌株和包含编码细胞色素P450的修饰的多核苷酸序列和/或编码细胞色素b5的修饰的多核苷酸序列的质粒。 已经显示本发明中公开的酵母菌株表达具有较高比活性的催化活性细胞色素P450

公开(公告)号：WO2010134096A3

公开(公告)日：2011-03-17

申请号：PCT/IN2010000322

申请日：2010-05-19

Applicant: PREMAS BIOTECH PVT LTD ,  SONI RAJEEV ,  KUNDU PRABUDDHA KUMAR ,  ARORA KAJAL ,  RAO PURNA CHANDRA ,  BHALLA KUNAL ,  SUMAN SUNIL KUMAR ,  KUMAR VIPUL

Inventor： SONI RAJEEV ,  KUNDU PRABUDDHA KUMAR ,  ARORA KAJAL ,  RAO PURNA CHANDRA ,  BHALLA KUNAL ,  SUMAN SUNIL KUMAR ,  KUMAR VIPUL

IPC: C07K14/80 ,  C12N9/02

CPC classification number: C12N9/0071 ,  C12N15/81 ,  C12Q1/26 ,  C12Y114/14001 ,  G01N2333/90209

Abstract: The present invention provides modified polynucleotide sequences coding for human cytochrome P450 reductase, human cytochrome P450 and human cytochrome b5. Further a genetically modified protease deficient yeast strain comprising integrated modified human cytochrome P450 reductase gene is provided in the present invention. The present invention also provides a genetically modified protease deficient yeast strain comprising integrated modified human cytochrome P450 reductase gene and a plasmid comprising modified polynucleotide sequence coding for cytochrome P450s and/or modified polynucleotide sequence coding for cytochrome b5. The yeast strain(s) disclosed in the present invention have been shown to express catalytically active cytochrome P450s with higher specific activity

Abstract translation: 本发明提供了编码人细胞色素P450还原酶，人细胞色素P450和人细胞色素b5的修饰的多核苷酸序列。 此外，在本发明中提供了包含整合的修饰的人细胞色素P450还原酶基因的遗传修饰的蛋白酶缺陷型酵母菌株。 本发明还提供了包含整合的修饰的人细胞色素P450还原酶基因的遗传修饰的蛋白酶缺陷型酵母菌株和包含编码细胞色素P450的修饰的多核苷酸序列和/或编码细胞色素b5的修饰的多核苷酸序列的质粒。 已经显示本发明中公开的酵母菌株表达具有较高比活性的催化活性细胞色素P450

公开(公告)号：WO2010134095A3

公开(公告)日：2011-03-17

申请号：PCT/IN2010000321

申请日：2010-05-19

Applicant: PREMAS BIOTECH PVT LTD ,  SONI RAJEEV ,  KUNDU PRABUDDHA KUMAR ,  ARORA KAJAL ,  RAO PURNA CHANDRA ,  BHALLA KUNAL ,  SUMAN SUNIL KUMAR ,  KUMAR VIPUL

Inventor： SONI RAJEEV ,  KUNDU PRABUDDHA KUMAR ,  ARORA KAJAL ,  RAO PURNA CHANDRA ,  BHALLA KUNAL ,  SUMAN SUNIL KUMAR ,  KUMAR VIPUL

IPC: C07K14/80 ,  C12N9/02

CPC classification number: C12N9/0077 ,  C12N9/0042

Abstract: The present invention provides modified polynucleotide sequences coding for human cytochrome P450 reductase, human cytochrome P450 and human cytochrome b5. Further a genetically modified protease deficient yeast strain comprising integrated modified human cytochrome P450 reductase gene is provided in the present invention. The present invention also provides a genetically modified protease deficient yeast strain comprising integrated modified human cytochrome P450 reductase gene and a plasmid comprising modified polynucleotide sequence coding for cytochrome P450s and/or modified polynucleotide sequence coding for cytochrome b5. The yeast strain(s) disclosed in the present invention have been shown to express catalytically active cytochrome P450s with higher specific activity.

Abstract translation: 本发明提供了编码人细胞色素P450还原酶，人细胞色素P450和人细胞色素b5的修饰的多核苷酸序列。 此外，在本发明中提供了包含整合的修饰的人细胞色素P450还原酶基因的遗传修饰的蛋白酶缺陷型酵母菌株。 本发明还提供了包含整合的修饰的人细胞色素P450还原酶基因的遗传修饰的蛋白酶缺陷型酵母菌株和包含编码细胞色素P450的修饰的多核苷酸序列和/或编码细胞色素b5的修饰的多核苷酸序列的质粒。 已经显示本发明中公开的酵母菌株表达具有较高比活性的催化活性细胞色素P450。

公开(公告)号：WO2010134095A2

公开(公告)日：2010-11-25

申请号：PCT/IN2010/000321

申请日：2010-05-19

Applicant: PREMAS BIOTECH PVT. LTD ,  SONI, Rajeev ,  KUNDU, Prabuddha Kumar ,  ARORA, Kajal ,  RAO, Purna Chandra ,  BHALLA, Kunal ,  SUMAN, Sunil Kumar ,  KUMAR, Vipul

Inventor： SONI, Rajeev ,  KUNDU, Prabuddha Kumar ,  ARORA, Kajal ,  RAO, Purna Chandra ,  BHALLA, Kunal ,  SUMAN, Sunil Kumar ,  KUMAR, Vipul

IPC: C07K14/80

CPC classification number: C12N9/0077 ,  C12N9/0042

Abstract: The present invention provides modified polynucleotide sequences coding for human cytochrome P450 reductase, human cytochrome P450 and human cytochrome b5. Further a genetically modified protease deficient yeast strain comprising integrated modified human cytochrome P450 reductase gene is provided in the present invention. The present invention also provides a genetically modified protease deficient yeast strain comprising integrated modified human cytochrome P450 reductase gene and a plasmid comprising modified polynucleotide sequence coding for cytochrome P450s and/or modified polynucleotide sequence coding for cytochrome b5. The yeast strain(s) disclosed in the present invention have been shown to express catalytically active cytochrome P450s with higher specific activity.

Abstract translation: 本发明提供了编码人细胞色素P450还原酶，人细胞色素P450和人细胞色素b5的修饰的多核苷酸序列。 此外，在本发明中提供了包含整合的修饰的人细胞色素P450还原酶基因的遗传修饰的蛋白酶缺陷型酵母菌株。 本发明还提供了包含整合的修饰的人细胞色素P450还原酶基因的遗传修饰的蛋白酶缺陷型酵母菌株和包含编码细胞色素P450的修饰的多核苷酸序列和/或编码细胞色素b5的修饰的多核苷酸序列的质粒。 已经显示本发明中公开的酵母菌株表达具有较高比活性的催化活性细胞色素P450。