P53 PROTEIN FRAGMENTS AND USE THEREOF FOR DETECTING AND MONITORING DISEASED CONDITIONS
    2.
    发明申请
    P53 PROTEIN FRAGMENTS AND USE THEREOF FOR DETECTING AND MONITORING DISEASED CONDITIONS 审中-公开
    P53蛋白质片段及其用于检测和监测疾病的条件

    公开(公告)号:WO1994010306A1

    公开(公告)日:1994-05-11

    申请号:PCT/FR1993001082

    申请日:1993-11-02

    IPC分类号: C12N15/12

    CPC分类号: C07K14/4746 C07K14/82

    摘要: A p53 protein fragment peptide specifically reacting with antibodies to p53 in the body fluids of cancer patients or precarcinomatous individuals. The peptide is preferably included in amino acid sequence 1-112 or 350-393 of protein p53, and may be used for detecting or monitoring diseased conditions, particularly carcinous conditions.

    摘要翻译: 与癌症患者或癌前病人体液中p53的抗体特异性反应的p53蛋白质片段肽。 肽优选包括在蛋白质p53的氨基酸序列1-112或350-393中,并且可以用于检测或监测患病条件,特别是致癌条件。

    NEW DERIVATIVES OF TETRAHYDRO-2,3,6,7,1H,5H,11H-(1)BENZOPYRANO(6,7,8,ij)QUINOLIZONONE-11 USABLE AS MARKERS FOR ORGANIC COMPOUNDS FOR THE PURPOSE OF DETECTING SAID COMPOUNDS BY CHEMILUMINESCENCE OR FLUORESCENCE
    3.
    发明申请
    NEW DERIVATIVES OF TETRAHYDRO-2,3,6,7,1H,5H,11H-(1)BENZOPYRANO(6,7,8,ij)QUINOLIZONONE-11 USABLE AS MARKERS FOR ORGANIC COMPOUNDS FOR THE PURPOSE OF DETECTING SAID COMPOUNDS BY CHEMILUMINESCENCE OR FLUORESCENCE 审中-公开
    四氰基-2,3,6,7,1H,5H,11H-(1)苯并噻吩(6,7,8,ij)喹诺酮酮的新衍生物可用作有机化合物标记,用于通过显微镜检测化合物的目的 或荧光

    公开(公告)号:WO1989012052A1

    公开(公告)日:1989-12-14

    申请号:PCT/FR1989000277

    申请日:1989-06-02

    IPC分类号: C07D491/16

    CPC分类号: C07D491/16

    摘要: The invention concerns new derivatives of tetrahydro-2,3,6,7,1H,5H,11H-(1)benzopyrano (6,7,8,ij)quinolizinone in accordance with formula (I), in which R represents a radical having formula (II), wherein m is equal to 0 or 1, and n is equal to 0 or is a whole number between 1 and 12, provided that n is equal to 0 when m is 0, or the radical having the formula: -NH-(CH2)n-NH2, in which n has the above meaning. Said derivatives can be used as markers for organic compounds, in order to detect them by chemiluminescence or fluorescence.

    摘要翻译: 本发明涉及根据式(I)的四氢-2,3,6,7,1H,5H,11H-(1)苯并吡喃酮(6,7,8,ij)喹嗪酮的新衍生物,其中R 1, 表示具有式(II)的基团,其中m等于0或1,并且n等于0或者为1至12之间的整数,条件是当m为0时n等于0,或者具有 式:-NH-(CH 2)n -NH 2,其中n具有上述含义。 所述衍生物可用作有机化合物的标记物,以便通过化学发光或荧光检测它们。

    MILIEU DE CONSERVATION D'ORGANES, DE TISSUS BIOLOGIQUES OU DE CELLULES VIVANTES
    4.
    发明申请
    MILIEU DE CONSERVATION D'ORGANES, DE TISSUS BIOLOGIQUES OU DE CELLULES VIVANTES 审中-公开
    用于保存器官,生物组织或生命细胞的介质

    公开(公告)号:WO2011018485A1

    公开(公告)日:2011-02-17

    申请号:PCT/EP2010/061713

    申请日:2010-08-11

    发明人: TRAN, Quang

    IPC分类号: C12N5/071 A01N1/02

    CPC分类号: C12N5/0621 A01N1/0215

    摘要: La présente invention a pour objet un nouveau milieu de conservation d'organes, de tissus biologiques ou de cellules vivantes, en particulier de cornées humaines vivantes, comprenant de la Natamycine comme antifongique, l'utilisation d'un tel milieu ainsi qu'un procédé de conservation utilisant un tel milieu.

    摘要翻译: 本发明涉及一种用于保存器官,生物组织或活细胞,特别是活人角膜的新型培养基,包括使用这种培养基的游霉素作为抗真菌剂,以及使用这种培养基的保存方法 中。

    METHOD FOR DETECTING A MUTATION INVOLVED IN ALZHEIMER'S DISEASE AND NUCLEOTIDE SEQUENCES FOR IMPLEMENTING SAME
    5.
    发明申请
    METHOD FOR DETECTING A MUTATION INVOLVED IN ALZHEIMER'S DISEASE AND NUCLEOTIDE SEQUENCES FOR IMPLEMENTING SAME 审中-公开
    用于检测阿尔茨海默氏病涉及的突变的方法和用于实施其的核苷酸序列

    公开(公告)号:WO1996025517A1

    公开(公告)日:1996-08-22

    申请号:PCT/FR1996000263

    申请日:1996-02-19

    IPC分类号: C12Q01/68

    CPC分类号: C12Q1/6883 C12Q2600/156

    摘要: Method for detecting, in a DNA preparation, a mutation involved in Alzheimer's disease, by determining the presence, in the apolipoprotein E gene, of one of the following nucleotide sequences, designated as SEQ ID N DEG 1, SEQ ID N DEG 3 and SEQ ID N DEG 5: SEQ ID N DEG 1: TGC GGC CGC; SEQ ID N DEG 3: TGC GAC CGC; SEQ ID N DEG 5: CGC GAC CGC. The determination is achieved by polymerase chain reaction (PCR) or sequencing techniques.

    摘要翻译: 在DNA制剂中通过测定载脂蛋白E基因中存在以下核苷酸序列之一(命名为SEQ ID NO:1,SEQ ID NO:3和SEQ ID NO:3)的方法,在DNA制备中检测参与阿尔茨海默氏病的突变 ID N DEG 5:SEQ ID N DEG 1:TGC GGC CGC; SEQ ID N DEG 3:TGC GAC CGC; SEQ ID N DEG 5:CGC GAC CGC。 通过聚合酶链反应(PCR)或测序技术测定。