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公开(公告)号：WO2011104687A1
公开(公告)日：2011-09-01
申请号：PCT/IB2011/050792
申请日：2011-02-24
Applicant: RINAT NEUROSCIENCE CORPORATION , LIN, Chia-Yang , LEE, Li-Fen , ZHAI, Wenwu
Inventor： LIN, Chia-Yang , LEE, Li-Fen , ZHAI, Wenwu
CPC classification number: C07K16/2866 , A61K2039/505 , C07K2317/14 , C07K2317/34 , C07K2317/51 , C07K2317/515 , C07K2317/52 , C07K2317/565 , C07K2317/76 , C07K2317/92
Abstract: The present invention provides antagonizing antibodies that bind to interleukin-7 receptor (IL-7R). The invention further provides a method of obtaining such antibodies and antibody-encoding nucleic acids. The invention further relates to therapeutic methods for use of these antibodies and antigen-binding portions thereof for the treatment and/or prevention of type 2 diabetes and immunological disorders, including type 1 diabetes, multiple sclerosis, rheumatoid arthritis, graft-versus-host disease, and lupus.
Abstract translation: 本发明提供了结合白细胞介素-7受体（IL-7R）的拮抗性抗体。 本发明还提供了获得这样的抗体和抗体编码核酸的方法。 本发明还涉及这些抗体及其抗原结合部分用于治疗和/或预防2型糖尿病和免疫学障碍（包括1型糖尿病，多发性硬化症，类风湿性关节炎，移植物抗宿主病）的治疗方法 ，和狼疮。
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公开(公告)号：WO2011100307A1
公开(公告)日：2011-08-18
申请号：PCT/US2011/024173
申请日：2011-02-09
Applicant: GOOGLE INC. , SONI, Punit , LEE, Steven J. , MAVINKURVE, Sanjay , GILBERT, Fred , WHITT, Carlos E. , VAZQUEZ, Ana Maria Ulin , LEE, Li-Wei , WILSON, Marc Peter Tarca , BALEZ, Mathieu P. , KENNBERG, Aleksandr
Inventor： SONI, Punit , LEE, Steven J. , MAVINKURVE, Sanjay , GILBERT, Fred , WHITT, Carlos E. , VAZQUEZ, Ana Maria Ulin , LEE, Li-Wei , WILSON, Marc Peter Tarca , BALEZ, Mathieu P. , KENNBERG, Aleksandr
IPC: G06F3/00
Abstract: Some techniques feature a computer-implemented method for messages associated with a user location. The method involves determining, by a mobile computing device, an estimated geographic location of the mobile computing device. The method includes receiving, at the mobile computing device, one or more messages associated with an area within the estimated geographic location, where the one or more messages include messages posted by users of a system that associates messages that those users posted about the area within the estimated geographic location. The method involves providing, on a display of the mobile computing device, one or more posted message icons that are presented in a layer over a map, where the one or more posted message icons represent the one or more posted messages. In a system, the one or more posted messages may not appear on mobile devices after a predetermined amount of time from their respective postings.
Abstract translation: 一些技术的特征在于用于与用户位置相关联的消息的计算机实现的方法。 该方法包括由移动计算设备确定移动计算设备的估计地理位置。 该方法包括在移动计算设备处接收与估计的地理位置内的区域相关联的一个或多个消息，其中一个或多个消息包括系统的用户发布的消息，该消息将那些用户在该区域内张贴的消息相关联 估计的地理位置。 该方法包括在移动计算设备的显示器上提供在地图上的层中呈现的一个或多个发布的消息图标，其中一个或多个发布的消息图标表示一个或多个发布的消息。 在系统中，一个或多个发布的消息在它们各自的发布之后的预定时间量之后可能不会出现在移动设备上。
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3.发明申请SYSTEMS AND METHODS FOR REDUCING DRAG AND/OR VORTEX INDUCED VIBRATION 审中-公开用于减少DRAG和/或VORTEX诱导振动的系统和方法
公开(公告)号：WO2010129222A3
公开(公告)日：2011-04-07
申请号：PCT/US2010032383
申请日：2010-04-26
Applicant: SHELL OIL CO , SHELL INT RESEARCH , ALLEN DONALD WAYNE , HENNING DEAN LEROY , LEE LI
Inventor： ALLEN DONALD WAYNE , HENNING DEAN LEROY , LEE LI
CPC classification number: E21B17/012 , E21B17/01 , F15D1/10
Abstract: A system for reducing drag and/or vortex induced vibration of a structure, the system comprising a multiple finned device comprising from at least one long fin having a first average height and at least one short fin having a second average height, wherein the height is a radial distance extending outwardly from the structure, and wherein the first average height is at least 10% larger than the second average height.
Abstract translation: 一种用于减少结构的阻力和/或涡流引起的振动的系统，所述系统包括多个带翅片的装置，其包括具有第一平均高度的至少一个长翅片和具有第二平均高度的至少一个短鳍片，其中， 从所述结构向外延伸的径向距离，并且其中所述第一平均高度比所述第二平均高度大至少10％。
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公开(公告)号：WO2010126971A2
公开(公告)日：2010-11-04
申请号：PCT/US2010/032713
申请日：2010-04-28
Applicant: SHELL OIL COMPANY , SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. , ALLEN, Donald Wayne , ARMSTRONG, Stephen Paul , DEHNE, Julie Ann , HENNING, Dean Leroy , LEE, Li , MCMILLAN, Damon Michael , WEST, Christopher Steven , MCMILLAN, Janet Kay
Inventor： ALLEN, Donald Wayne , ARMSTRONG, Stephen Paul , DEHNE, Julie Ann , HENNING, Dean Leroy , LEE, Li , MCMILLAN, Damon Michael , WEST, Christopher Steven
CPC classification number: B63B39/005 , E21B17/012
Abstract: A system for reducing drag and/or vortex induced vibration of a structure, the system comprising a multiple sided device comprising from 4 to 6 sides; and at least one blade located extending from the multiple sided device.
Abstract translation: 一种用于减少结构的阻力和/或涡流引起的振动的系统，所述系统包括包括4至6个侧面的多边设备; 以及至少一个位于从所述多边设备延伸的刀片。
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公开(公告)号：WO2009089446A3
公开(公告)日：2009-09-11
申请号：PCT/US2009030592
申请日：2009-01-09
Applicant: JOHNSON CONTROLS TECH CO , SCHREIBER JEB , KOHLER JAY A , DE LARMINAT PAUL , YANIK MUSTAFA KEMAL , MCQUADE WILLIAM F , KAUFFMAN JUSTIN , POULSEN SOREN BIERRE , WANG LEE LI , KULANKARA SATHEESH
Inventor： SCHREIBER JEB , KOHLER JAY A , DE LARMINAT PAUL , YANIK MUSTAFA KEMAL , MCQUADE WILLIAM F , KAUFFMAN JUSTIN , POULSEN SOREN BIERRE , WANG LEE LI , KULANKARA SATHEESH
CPC classification number: F25B41/04 , F25B39/028 , F25B2339/0242 , F25B2400/13 , F28D3/02 , F28D3/04 , F28D7/16 , F28D21/0017 , F28D2021/0071 , F28F9/22 , F28F25/06 , F28F2280/02
Abstract: An evaporator (168) in a vapor compression system (14) (168) includes a shell (76), a first tube bundle (78); a hood (86); a distributor (80); a first supply line (142); a second supply line (144); a valve (122) positioned in the second supply line (144); and a sensor (150). The distributor (80) is positioned above the first tube bundle (78). The hood (88) covers the first tube bundle (78). The first supply line (142) is connected to the distributor (80) and an end of the second supply line (144) is positioned near the hood (88). The sensor (150) is configured and positioned to sense a level of liquid refrigerant (82) in the shell. The valve (122) regulates flow in the second supply line in response to the level of liquid refrigerant (82) from the sensor (150).
Abstract translation: 蒸汽压缩系统（14）（168）中的蒸发器（168）包括壳体（76），第一管束（78）; 罩（86）; 分销商（80）; 第一供应管线（142）; 第二供应管线（144）; 位于所述第二供应管线（144）中的阀（122）; 和传感器（150）。 分配器（80）位于第一管束（78）上方。 罩（88）覆盖第一管束（78）。 第一供应管线（142）连接到分配器（80），并且第二供应管线（144）的端部位于罩（88）附近。 传感器（150）被构造和定位成感测外壳中的液体制冷剂（82）的水平。 响应于来自传感器（150）的液体制冷剂（82）的水平，阀（122）调节第二供应管线中的流量。
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Patent Agency Ranking6.发明申请SYSTEMS AND METHODS FOR REDUCING DRAG AND/OR VORTEX INDUCED VIBRATION 审中-公开用于减少DRAG和/或VORTEX诱导振动的系统和方法
公开(公告)号：WO2009046166A1
公开(公告)日：2009-04-09
申请号：PCT/US2008/078541
申请日：2008-10-02
Applicant: SHELL OIL COMPANY , SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. , ALLEN, Donald Wayne , HENNING, Dean Leroy , LEE, Li
Inventor： ALLEN, Donald Wayne , HENNING, Dean Leroy , LEE, Li
IPC: F15D1/10
CPC classification number: F15D1/10 , B63B21/502 , B63B39/005 , B63B2021/504 , B63B2035/442 , E02B17/0017 , F16L1/123
Abstract: A system for reducing drag and/or vortex induced vibration of a structure, the system comprising a multiple finned device comprising from 4 to 6 fins substantially aligned along a longitudinal axis of the structure.
Abstract translation: 一种用于减小结构的阻力和/或涡流引起的振动的系统，所述系统包括多个带翅片的装置，所述多个翅片装置包括基本上沿着所述结构的纵向轴线对齐的4至6个翅片。
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7.发明申请SYSTEMS AND METHODS FOR REDUCING DRAG AND/OR VORTEX INDUCED VIBRATION 审中-公开用于减少DRAG和/或VORTEX诱导振动的系统和方法
公开(公告)号：WO2008064104A2
公开(公告)日：2008-05-29
申请号：PCT/US2007/084920
申请日：2007-11-16
Applicant: SHELL OIL COMPANY , SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. , ALLEN, Donald Wayne , HENNING, Dean Leroy , LEE, Li , MCMILLAN, David Wayne
Inventor： ALLEN, Donald Wayne , HENNING, Dean Leroy , LEE, Li , MCMILLAN, David Wayne
IPC: B64C23/06
CPC classification number: B63B21/502 , B63B2021/504 , E02B17/0017 , F15D1/10 , F16L1/123
Abstract: There is disclosed a system for reducing drag and/or vortex induced vibration of a structure, the system comprising a fairing moveable from a short fairing configuration to a long fairing configuration.
Abstract translation: 公开了一种用于减小结构的阻力和/或涡流引起的振动的系统，该系统包括可从短的整流罩构型移动到长的整流罩构造的整流罩。
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公开(公告)号：WO2008064102A3
公开(公告)日：2008-05-29
申请号：PCT/US2007/084918
申请日：2007-11-16
Applicant: SHELL OIL COMPANY , SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. , ALLEN, Donald Wayne , HENNING, Dean Leroy , LEE, Li , MCMILLAN, David Wayne
Inventor： ALLEN, Donald Wayne , HENNING, Dean Leroy , LEE, Li , MCMILLAN, David Wayne
IPC: B63B21/66
Abstract: There is disclosed a system for reducing drag and/or vortex induced vibration of a structure, the system comprising a fairing comprising a dampening mechanism adapted to dampen the rotation of the fairing about the structure.
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公开(公告)号：WO2007059026A1
公开(公告)日：2007-05-24
申请号：PCT/US2006/043979
申请日：2006-11-13
Applicant: SHELL OIL COMPANY , ALLEN, Donald Wayne , LEE, Li , MCMULLEN, Clay Douglas
Inventor： ALLEN, Donald Wayne , LEE, Li , MCMULLEN, Clay Douglas
IPC: G01M5/00
CPC classification number: G01M5/0025 , B63B9/00 , E21B17/01 , G01M5/0041 , G01M5/0066
Abstract: There is disclosed a system comprising a structure, from 1 to 10 dynamic tension sensors, adapted to monitor a dynamic tension level of at least one point along a length of the structure, and a controller adapted to calculate a dynamic bending stress or strain level at a plurality of points along the length of the structure as a function of time. In some embodiments, the system also includes a vessel connected to the structure, wherein the vessel is floating in a body of water.
Abstract translation: 公开了一种系统，其包括结构，1至10个动态张力传感器，其适于监测沿着结构的长度的至少一个点的动态张力水平，以及控制器，适于计算动态弯曲应力或应变水平 沿着结构长度的多个点作为时间的函数。 在一些实施例中，系统还包括连接到结构的容器，其中容器浮在水体中。
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10.发明申请SYSTEMS AND METHODS FOR REDUCING DRAG AND/OR VORTEX INDUCED VIBRATION 审中-公开用于减少DRAG和/或VORTEX诱导振动的系统和方法
公开(公告)号：WO2006138354A3
公开(公告)日：2007-04-12
申请号：PCT/US2006023131
申请日：2006-06-14
Applicant: SHELL OIL CO , ALLEN DONALD WAYNE , LEE LI , MENON RAGHUNATH GOPAL , WORTHEN RACHEL ANNA
Inventor： ALLEN DONALD WAYNE , LEE LI , MENON RAGHUNATH GOPAL , WORTHEN RACHEL ANNA
IPC: E02D5/60
CPC classification number: E02D27/52
Abstract: There is disclosed a system for reducing drag and/or vortex induced vibration of a structure, the system comprising a fairing defining a plurality of perforations, wherein the fairing is suitable for placement around the structure, the perforations defining a porosity of the fairing of at least 1%.
Abstract translation: 公开了一种用于减小结构的阻力和/或涡流引起的振动的系统，该系统包括限定多个穿孔的整流罩，其中整流罩适于放置在结构周围，穿孔限定了整流罩的孔隙度 至少1％。
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