公开(公告)号：WO2012033359A2

公开(公告)日：2012-03-15

申请号：PCT/KR2011006647

申请日：2011-09-08

Applicant: SK INNOVATION CO LTD ,  KANG SIN YOUNG ,  KOO MIN SU ,  CHO IN HO ,  LEE JOON SIK ,  PARK EUN HEE ,  PARK JOONG MIN ,  PARK JAE YEON ,  CHU YOUNG HWAN ,  KIM DONG HYUN ,  PARK WOO CHAN ,  LEE SEUNG YEOP ,  RYU JAE WOOK

Inventor： KANG SIN YOUNG ,  KOO MIN SU ,  CHO IN HO ,  LEE JOON SIK ,  PARK EUN HEE ,  PARK JOONG MIN ,  PARK JAE YEON ,  CHU YOUNG HWAN ,  KIM DONG HYUN ,  PARK WOO CHAN ,  LEE SEUNG YEOP ,  RYU JAE WOOK

IPC: C12P7/52 ,  C07C59/01 ,  C12N1/20 ,  C12R1/145

CPC classification number: C12P7/62 ,  C07C51/02 ,  C07C51/48 ,  C12P7/52 ,  C07C53/124

Abstract: Disclosed is a method of preparing alkyl butyrate, which comprises: (a) producing a fermented liquid containing butyrate salt through a fermentation process using butyric acid-producing strains; (b) obtaining an extracted liquid containing butyric acid from a continuous extracting apparatus using an extraction solvent, after converting the butyrate salt into butyric acid by adding an inorganic acid except for carbonic acid or carbon dioxide into the fermented liquid, wherein the continuous extracting apparatus includes a plurality of extraction terminals which are installed inside an extraction column and perform a reciprocating motion vertically, and the fermented liquid and the extracted liquid are supplied to upper and lower portions of the column, respectively; and (c) reacting the extracted liquid and alcohol having a carbon number of 4 or less or a mixture thereof in an esterification reactor to convert a resultant product into alkyl butyrate. According to the present invention, butyric acid existing in microbic culture fluid can be efficiently extracted, and furthermore, competitively priced alkyl butyrate can be prepared without an additional process of separating the extracted solvent while minimizing energy consumption.

Abstract translation: 公开了一种制备丁酸烷基酯的方法，该方法包括：（a）通过使用丁酸生产菌株的发酵工艺生产含有丁酸盐的发酵液体; （b）通过向所述发酵液中添加除碳酸或二氧化碳以外的无机酸，将所述丁酸盐转化为丁酸后，从连续提取装置使用提取溶剂得到含有丁酸的提取液，其中，所述连续提取装置 包括多个提取终端，所述提取终端被安装在提取柱内部并且竖直地进行往复运动，并且所述发酵液和提取液分别被提供给所述柱的上部和下部; （c）使提取的液体和碳数为4或更少的醇或其混合物在酯化反应器中反应以将所得产物转化为丁酸烷基酯。 根据本发明，可以有效地提取存在于微生物培养液中的丁酸，并且此外，可以制备竞争价格的丁酸烷基酯，而无需另外的分离提取的溶剂的工艺，同时使能量消耗最小化。

公开(公告)号：WO2009134023A3

公开(公告)日：2010-01-21

申请号：PCT/KR2009001939

申请日：2009-04-15

Applicant: POSTECH ACAD IND FOUND ,  HWANG SEOK HWAN ,  LIM JUN TAEK ,  LEE SEUNG YEOP ,  CHO KYUNG JIN

Inventor： HWANG SEOK HWAN ,  LIM JUN TAEK ,  LEE SEUNG YEOP ,  CHO KYUNG JIN

IPC: C02F3/20

CPC classification number: C02F3/101 ,  C02F3/006 ,  C02F3/06 ,  C02F2209/02 ,  C02F2209/06 ,  C02F2209/22 ,  Y02W10/15

Abstract: The present invention relates to a biofilm reactor containing a spiral structure and a water treatment device using the same. The biofilm reactor of the present invention comprises: a water inlet pipe; an air inlet pipe; and an outlet pipe which discharges water and air that has entered through the inlet pipes and passed through the inside of the reactor. In order to induce the flow of air bubbles from the air inlet pipe and raise the oxygen transfer rate by increasing residence time, the spiral structure is inserted inside the reactor, wherein the spiral structure forms a spiral flow path from the air inlet pipe to the outlet pipe. Also, since the biofilm is formed on the spiral structure through adhesion of microorganisms, the microorganism growth conditions for both suspended growth and attached growth are prepared at the same time. Moreover, dissolved oxygen concentration in water is efficiently increased without consumption of power for stirring. Also, the invention has an effect of increasing and maintaining the concentration of microorganisms.

Abstract translation: 本发明涉及含有螺旋结构的生物膜反应器和使用其的水处理装置。 本发明的生物膜反应器包括：进水管; 进气管; 以及排出已经通过入口管进入并通过反应器内部的水和空气的出口管。 为了引入空气入口管的气泡流动，通过增加停留时间来提高氧气传输速率，将螺旋结构插入反应器内，其中螺旋结构形成从空气入口管到 出口管。 此外，由于通过微生物的粘附在螺旋结构上形成生物膜，所以同时制备用于悬浮生长和附着生长的微生物生长条件。 此外，水中的溶解氧浓度有效地增加而不消耗搅拌功率。 此外，本发明具有增加和维持微生物浓度的作用。

公开(公告)号：WO2011115416A2

公开(公告)日：2011-09-22

申请号：PCT/KR2011001815

申请日：2011-03-15

Applicant: DBIO INC ,  SUNG CHANG KEUN ,  MO EUN KYOUNG ,  KIM SEUNG MI ,  YANG SEON AH ,  LEE CHUNG HA ,  JO HYUN HO ,  KIM HYUN HO ,  LEE SEUNG YEOP

Inventor： SUNG CHANG KEUN ,  MO EUN KYOUNG ,  KIM SEUNG MI ,  YANG SEON AH ,  LEE CHUNG HA ,  JO HYUN HO ,  KIM HYUN HO ,  LEE SEUNG YEOP

IPC: A61K36/41 ,  A61P25/32

CPC classification number: A61K36/41

Abstract: The present invention relates to a Sedum sarmentosum fraction, which has excellent alcohol breakdown and hangover relief performance. An ethyl acetate fraction of the alcohol extract of Sedum sarmentosum facilitates the activities of ADH and ALDH, which are liver enzymes associated with alcohol metabolism, and thus relieves hangover symptoms such as thirst, general weakness, fatigue or the like, which are side effects caused by alcohol intake. The activation of ADH and ALDH enables ethanol to be quickly broken down into acetic acid which is the end product of alcohol metabolism, thereby reducing liver damage caused by alcohol intake, and improving resistance to a variety of diseases caused by alcohol intake.

Abstract translation: 本发明涉及一种具有优异的酒精分解和宿醉缓解性能的Sedum sarmentosum级分。 Sedum sarmentosum的酒精提取物的乙酸乙酯部分有助于ADH和ALDH的活性，其是与酒精代谢相关的肝酶，从而减轻了引起的副作用的解渴症状，一般无力，疲劳等等的宿醉症状 通过酒精摄入。 ADH和ALDH的激活使乙醇快速分解成乙醇，这是乙醇代谢的最终产物，从而减少酒精摄入引起的肝脏损伤，改善对酒精摄入引起的各种疾病的抵抗力。

公开(公告)号：WO2012033359A3

公开(公告)日：2012-05-31

申请号：PCT/KR2011006647

申请日：2011-09-08

Applicant: SK INNOVATION CO LTD ,  KANG SIN YOUNG ,  KOO MIN SU ,  CHO IN HO ,  LEE JOON SIK ,  PARK EUN HEE ,  PARK JOONG MIN ,  PARK JAE YEON ,  CHU YOUNG HWAN ,  KIM DONG HYUN ,  PARK WOO CHAN ,  LEE SEUNG YEOP ,  RYU JAE WOOK

Inventor： KANG SIN YOUNG ,  KOO MIN SU ,  CHO IN HO ,  LEE JOON SIK ,  PARK EUN HEE ,  PARK JOONG MIN ,  PARK JAE YEON ,  CHU YOUNG HWAN ,  KIM DONG HYUN ,  PARK WOO CHAN ,  LEE SEUNG YEOP ,  RYU JAE WOOK

IPC: C12P7/52 ,  C07C59/01 ,  C12N1/20 ,  C12R1/145

CPC classification number: C12P7/62 ,  C07C51/02 ,  C07C51/48 ,  C12P7/52 ,  C07C53/124

Abstract: Disclosed is a method of preparing alkyl butyrate, which comprises: (a) producing a fermented liquid containing butyrate salt through a fermentation process using butyric acid-producing strains; (b) obtaining an extracted liquid containing butyric acid from a continuous extracting apparatus using an extraction solvent, after converting the butyrate salt into butyric acid by adding an inorganic acid except for carbonic acid or carbon dioxide into the fermented liquid, wherein the continuous extracting apparatus includes a plurality of extraction terminals which are installed inside an extraction column and perform a reciprocating motion vertically, and the fermented liquid and the extracted liquid are supplied to upper and lower portions of the column, respectively; and (c) reacting the extracted liquid and alcohol having a carbon number of 4 or less or a mixture thereof in an esterification reactor to convert a resultant product into alkyl butyrate. According to the present invention, butyric acid existing in microbic culture fluid can be efficiently extracted, and furthermore, competitively priced alkyl butyrate can be prepared without an additional process of separating the extracted solvent while minimizing energy consumption.