公开(公告)号：WO1990008125A2

公开(公告)日：1990-07-26

申请号：PCT/EP1990000105

申请日：1990-01-19

Applicant: NATTERMANN, A. & CIE. GMBH ,  GÜNTHER, Bernd, Rainer ,  LOSCH, Rainer ,  LAUTENSCHLÄGER, Hans ,  STEINER, Klaus

Inventor： NATTERMANN, A. & CIE. GMBH

IPC: C07C59/01

CPC classification number: C07C59/01 ,  C07C51/367 ,  C07C51/38 ,  C07C59/245

Abstract: The invention refers to a novel method for the preparation of 8-hydroxyoctanoic acid by reaction of 6-chlorohexanol with a dialkyl malonate ester, thermal decarboxylation of the malonic acid derivative and isolation of the 8-hydroxyoctanoic acid as the free acid or as an alkali metal salt.

Abstract translation: 本发明涉及一种新的方法用于通过6-氯己醇的反应与丙二酸二烷基酯，在形式的8-羟基辛酸的丙二酸衍生物和隔离的热脱羧的酯制备8-羟基辛酸 游离酸或碱金属盐。