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公开(公告)号:WO2009033056A1
公开(公告)日:2009-03-12
申请号:PCT/US2008/075448
申请日:2008-09-05
Applicant: BIOSCALE, INC. , ARENAS, Jaime, E. , CHOI, Hyun-Goo , DICKERSON, William, Matthew , HEMBREE, Sarah, Beth , MADISON, Lara, Louise , MASTERS, Brett, P. , MILLER, Michael, F. , WANG, Wayne, U.
Inventor: ARENAS, Jaime, E. , CHOI, Hyun-Goo , DICKERSON, William, Matthew , HEMBREE, Sarah, Beth , MADISON, Lara, Louise , MASTERS, Brett, P. , MILLER, Michael, F. , WANG, Wayne, U.
IPC: G01N33/543 , G01N29/02
CPC classification number: G01N29/022 , B01L9/52 , G01N33/54373 , G01N2291/014 , G01N2291/0255 , G01N2291/0256 , G01N2291/02809 , G01N2291/02836 , G01N2291/0427
Abstract: The technology provided herein generally relates to reusable detection surfaces and methods for reusing a detection surface after using the detection surface in an assay for an analyte. In particular, the present application relates to a detection surface of an acoustic device, like flexural plate wave (FPW) device, wherein a first capture agent capable of binding an analyte is linked to the detection surface and remains linked to the detection surface upon removal of the bound analyte by chemical wash. Thus the detection surface can be reused in further assays. Furthermore the application claims a kit and a reusable cartridge with a fluid chamber, an acoustic device with detection surface and a first capturing agent.
Abstract translation: 本文提供的技术通常涉及可重复使用的检测表面和用于在分析物的测定中使用检测表面后重新使用检测表面的方法。 特别地,本申请涉及一种声学装置的检测表面,例如弯曲板波(FPW)装置,其中能够将分析物结合的第一捕获剂与检测表面连接,并且在去除时保持与检测表面的连接 的化学洗涤结合的分析物。 因此,检测表面可以再次用于进一步的检测。 此外,本申请要求具有流体室的套件和可重复使用的盒,具有检测表面的声学装置和第一捕获剂。