公开(公告)号：WO2011038487A1

公开(公告)日：2011-04-07

申请号：PCT/CA2010/001518

申请日：2010-09-29

Applicant: TSO3 INC. ,  ROBITAILLE , Simon ,  DUFRESNE , SyIvie ,  VALLIERES , Jean-Martin ,  MARTEL , Cynthia ,  LEBLOND , Helene ,  DASSIE , Nancy ,  GAGNE , Marie-Christine ,  MARTEL , Karine ,  BEDARD , Claudia ,  TREMBLAY , Bruno

Inventor： ROBITAILLE , Simon ,  DUFRESNE , SyIvie ,  VALLIERES , Jean-Martin ,  MARTEL , Cynthia ,  LEBLOND , Helene ,  DASSIE , Nancy ,  GAGNE , Marie-Christine ,  MARTEL , Karine ,  BEDARD , Claudia ,  TREMBLAY , Bruno

IPC: A61L2/20 ,  A61L2/24 ,  A61L2/26

CPC classification number: A61L2/202 ,  A61L2/20 ,  A61L2/208 ,  A61L2202/122 ,  A61L2202/13 ,  A61L2202/14 ,  A61L2202/24 ,  B65D23/001

Abstract: A method of sterilizing an article by sequentially exposing the article to hydrogen peroxide and ozone is disclosed. The article is exposed under vacuum first to an evaporated aqueous solution of hydrogen peroxide and subsequently to an ozone containing gas. The exposure is carried out without reducing the water vapor content of the sterilization atmosphere, the water vapor content being derived from the aqueous solvent of the hydrogen peroxide solution and from the decomposition of the hydrogen peroxide into water and oxygen. The complete sterilization process is carried out while the chamber remains sealed and without removal of any component of the sterilization atmosphere. For this purpose, the chamber is initially evacuated to a first vacuum pressure sufficient to cause evaporation of the aqueous hydrogen peroxide at the temperature of the chamber atmosphere. The chamber is then sealed for the remainder of the sterilization process and during all sterilant injection cycles. Keeping the chamber sealed and maintaining the hydrogen peroxide and its decomposition products in the chamber for the subsequent ozone sterilization step results in a synergistic increase in the sterilization efficiency and allows for the use of much lower sterilant amounts and sterilization cycle times than would be expected from using hydrogen peroxide and ozone in combination.

Abstract translation: 公开了通过将制品依次暴露于过氧化氢和臭氧来对制品进行灭菌的方法。 首先将制品在真空下暴露于蒸发的过氧化氢水溶液中，随后暴露于含臭氧气体。 曝光是在不降低灭菌气氛的水蒸汽含量的情况下进行的，水蒸汽含量来自过氧化氢溶液的水性溶剂，由过氧化氢分解成水和氧。 在室保持密封且不除去灭菌气氛的任何成分的情况下完成灭菌过程。 为此，腔室最初被抽空到第一真空压力，足以在室气氛的温度下引起过氧化氢水溶液的蒸发。 然后将腔室密封用于灭菌过程的剩余部分和所有灭菌剂注射循环期间。 保持室密封并将过氧化氢及其分解产物保持在室中用于随后的臭氧灭菌步骤导致灭菌效率的协同增加，并允许使用比预期的更低的杀菌剂量和灭菌循环时间 使用过氧化氢和臭氧组合使用。

公开(公告)号：WO2005030275A1

公开(公告)日：2005-04-07

申请号：PCT/CA2004/001637

申请日：2004-09-07

Applicant: TSO3 INC. ,  BÉDARD, Claudia ,  DUFRESNE, Sylvie ,  LEBLOND, Hélène ,  MARTEL, Cynthia ,  MARTEL, Karine

Inventor： BÉDARD, Claudia ,  DUFRESNE, Sylvie ,  LEBLOND, Hélène ,  MARTEL, Cynthia ,  MARTEL, Karine

IPC: A61L2/20

CPC classification number: A61L2/202

Abstract: The invention relates to an improvement in a method for sterilizing an article in a sterilizing chamber by exposing the article to humidified ozone in at least two consecutive sterilizing cycles, the improvement comprising, after the first of said consecutive sterilizing cycles and before the second of said consecutive sterilizing cycles, removing from the sterilizing chamber any condensed water present.

Abstract translation: 本发明涉及通过在至少两个连续的灭菌循环中将制品暴露于加湿的臭氧来消毒灭菌室中的物品的方法的改进，其改进包括在所述连续灭菌循环中的第一个之后和所述第二次灭菌循环之前 连续灭菌循环，从灭菌室中除去存在的任何冷凝水。