公开(公告)号：WO2005107829A3

公开(公告)日：2006-03-09

申请号：PCT/US2005014878

申请日：2005-04-29

Applicant: KENSEY NASH CORP ,  DEMEO JOSEPH ,  MCDADE ROBERT L ,  RINGEISEN TIMOTHY A ,  HEARN PATRICK E ,  TURNER AMANDA

Inventor： DEMEO JOSEPH ,  MCDADE ROBERT L ,  RINGEISEN TIMOTHY A ,  HEARN PATRICK E ,  TURNER AMANDA

IPC: A61F2/02 ,  A61F2/28 ,  A61F2/44 ,  A61L27/00 ,  A61L27/56

CPC classification number: A61B17/0642 ,  A61B17/7059 ,  A61B17/846 ,  A61B17/866 ,  A61F2/3094 ,  A61F2002/2817 ,  A61F2002/30014 ,  A61F2002/30032 ,  A61F2002/30036 ,  A61F2002/30062 ,  A61F2002/30235 ,  A61F2002/30563 ,  A61F2002/30578 ,  A61F2002/30677 ,  A61F2002/30904 ,  A61F2002/3092 ,  A61F2002/30971 ,  A61F2310/00293 ,  A61F2310/0097 ,  A61L27/56

Abstract: A high strength porous polymeric material manufactured by a compression and/or sintering process is disclosed. The material results in a network of interconnected collapsed pores, which forces thin overlapping walls and passages to be created. The network provides permeable access for fluid migration throughout the material. The strength and/or permeability are advantageous for medical devices and implants.

Abstract translation: 公开了通过压缩和/或烧结工艺制造的高强度多孔聚合材料。 该材料导致相互连接的塌陷孔的网络，这迫使薄的重叠壁和通道产生。 网络为整个材料的流体迁移提供可渗透性。 强度和/或渗透性对于医疗装置和植入物是有利的。

公开(公告)号：WO2005107829A2

公开(公告)日：2005-11-17

申请号：PCT/US2005/014878

申请日：2005-04-29

Applicant: KENSEY NASH CORPORATION ,  DEMEO, Joseph ,  MCDADE, Robert, L. ,  RINGEISEN, Timothy, A. ,  HEARN, Patrick, E. ,  TURNER, Amanda

Inventor： DEMEO, Joseph ,  MCDADE, Robert, L. ,  RINGEISEN, Timothy, A. ,  HEARN, Patrick, E. ,  TURNER, Amanda

IPC: A61L27/00

CPC classification number: A61B17/0642 ,  A61B17/7059 ,  A61B17/846 ,  A61B17/866 ,  A61F2/3094 ,  A61F2002/2817 ,  A61F2002/30014 ,  A61F2002/30032 ,  A61F2002/30036 ,  A61F2002/30062 ,  A61F2002/30235 ,  A61F2002/30563 ,  A61F2002/30578 ,  A61F2002/30677 ,  A61F2002/30904 ,  A61F2002/3092 ,  A61F2002/30971 ,  A61F2310/00293 ,  A61F2310/0097 ,  A61L27/56

Abstract: A high strength porous polymeric material manufactured by a compression and/or sintering process is disclosed. The material results in a network of interconnected collapsed pores, which forces thin overlapping walls and passages to be created. The network provides permeable access for fluid migration throughout the material. The strength and/or permeability are advantageous for medical devices and implants.

Abstract translation: 公开了通过压缩和/或烧结工艺制造的高强度多孔聚合材料。 这种材料导致相互连接的塌陷孔隙的网络，这促使要产生薄的重叠壁和通道。 网络为整个材料的流体迁移提供可渗透性。 强度和/或渗透性对于医疗装置和植入物是有利的。

公开(公告)号：WO2011002511A1

公开(公告)日：2011-01-06

申请号：PCT/US2010/001878

申请日：2010-06-30

Applicant: KENSEY NASH CORPORATION ,  CASTIGLIONE-DODD, Emme, M. ,  BRADICA, Gino ,  EBRAHIMI, Ali ,  RINGEISEN, Timothy, A. ,  WATTENGEL, William, Christian ,  MCDADE, Robert, L.

Inventor： CASTIGLIONE-DODD, Emme, M. ,  BRADICA, Gino ,  EBRAHIMI, Ali ,  RINGEISEN, Timothy, A. ,  WATTENGEL, William, Christian ,  MCDADE, Robert, L.

IPC: A61F2/28 ,  A61F2/30 ,  A61F2/00

CPC classification number: A61F2/28 ,  A61F2/30756 ,  A61F2002/30014 ,  A61F2002/30028 ,  A61F2002/30031 ,  A61F2002/30052 ,  A61F2002/30088 ,  A61F2002/30332 ,  A61F2002/3092 ,  A61F2002/30971 ,  A61F2002/4495 ,  A61F2210/008 ,  A61F2220/0033 ,  A61F2250/0018 ,  A61F2250/0043 ,  A61F2250/0051 ,  A61F2250/0056 ,  A61F2310/00365 ,  A61L27/24 ,  A61L27/48 ,  A61L27/50 ,  A61L27/52 ,  A61L27/56 ,  A61L2430/06

Abstract: Tissue implants prepared for the repair of tissues, especially avascular tissues such as cartilage. One embodiment presents an electric potential capable of receiving and accumulating desirable factors or molecules from surrounding fluid when exposed to dynamic loading. In another embodiment the implant promotes tissue conduction by retarding, restricting and controlling cellular invasion through use of gradients until competent tissue forms. Further embodiments of the tissue implants may be formed into a multi-phasic device that provides deep tissue mechanical stimulus by conduction of mechanical and fluid forces experienced at the surface of the implant.

Abstract translation: 组织植入物准备用于修复组织，特别是无血管组织如软骨。 一个实施例呈现出当暴露于动态载荷时能够从周围流体接收和积聚期望因子或分子的电势。 在另一个实施方案中，所述植入物通过使用梯度来延缓，限制和控制细胞侵袭直到感染组织形成来促进组织传导。 组织植入物的其它实施方案可以形成为通过在植入物表面经历的机械和流体力的传导而提供深层组织机械刺激的多相装置。