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    INCONTINENCE TREATMENT DEVICE AND METHOD OF TREATING INCONTINENCE
    3.
    发明申请
    INCONTINENCE TREATMENT DEVICE AND METHOD OF TREATING INCONTINENCE 审中-公开
    不良治疗装置及其治疗方法

    公开(公告)号：WO2011157274A9

    公开(公告)日：2012-03-01

    申请号：PCT/DK2011050213

    申请日：2011-06-14

    Applicant: COLOPLAST AS ,  WITZMANN MICHAEL M ,  DEVENS DOUGLAS ADELBERT

    Inventor： WITZMANN MICHAEL M ,  DEVENS DOUGLAS ADELBERT

    IPC: A61F2/00 ,  A61F7/12

    CPC classification number: A61F2/0045 ,  A61B17/0401 ,  A61B2017/00805 ,  A61B2017/0464 ,  A61F2210/008 ,  A61F2210/009 ,  A61F2250/0007

    Abstract: An incontinence treatment device includes a urethral support and first and second connectors. The urethral support extends between a first end and a second end and has porosity that is configured to allow tissue in-growth through the urethral support. The first connector is attached to the first end of the urethral support and the second connector is attached to the second end of the urethral support. At least one of the first connector and the second connector is a cross- linked polymer connector having a glass transition temperature between 40-70 degrees Celsius. The cross-linked polymer connector has an initial length that is elongated to an implant length that is greater than the initial length. Means for heating the cross-linked polymer connector from an extracorporeal location through intact skin is provided, thereby shortening the cross-linked polymer connector.

    Abstract translation: 失禁治疗装置包括尿道支撑件和第一和第二连接器。 尿道支撑件在第一端和第二端之间延伸并且具有构造成允许组织通过尿道支撑生长的多孔性。 第一连接器连接到尿道支撑件的第一端，第二连接器连接到尿道支撑件的第二端。 第一连接器和第二连接器中的至少一个是玻璃化转变温度在40-70摄氏度之间的交联聚合物连接器。 交联聚合物连接器具有延伸到大于初始长度的植入物长度的初始长度。 提供了通过完整皮肤从体外位置加热交联聚合物连接器的手段，从而缩短了交联聚合物连接器。

    ADJUSTABLE OPTICAL ELEMENT WITH MULTIZONE POLYMERIZATION
    4.
    发明申请
    ADJUSTABLE OPTICAL ELEMENT WITH MULTIZONE POLYMERIZATION 审中-公开
    可调整的光学元件与多光子聚合

    公开(公告)号：WO2006096193A3

    公开(公告)日：2007-05-03

    申请号：PCT/US2005020699

    申请日：2005-06-09

    Applicant: MINU LLC ,  PEYMAN GHOLAM A

    Inventor： PEYMAN GHOLAM A

    IPC: A61B18/18

    CPC classification number: A61F2/147 ,  A61F2210/008 ,  A61F2250/0001 ,  A61F2250/0048 ,  A61L27/16

    Abstract: The present invention relates to an optical element for correcting refractive error in an eye. The optical element includes a first portion having a first volume that remains substantially constant when exposed to an energy, and a second portion having a second volume that is adapted to change when exposed to the energy. This optical element results in a device that can correct severe ametropic conditions, without ablating any portion of the element itself or the cornea.

    Abstract translation: 本发明涉及一种用于校正眼睛屈光不正的光学元件。 光学元件包括第一部分，其具有当暴露于能量时保持基本恒定的第一体积，以及具有适于在暴露于能量时改变的第二体积的第二部分。 该光学元件产生可以校正严重的变态条件而不消除元件本身或角膜的任何部分的装置。

    ROTATABLE CATHETER ASSEMBLY
    5.
    发明申请
    ROTATABLE CATHETER ASSEMBLY 审中-公开
    可旋转导管总成

    公开(公告)号：WO2005082280A1

    公开(公告)日：2005-09-09

    申请号：PCT/US2004/038596

    申请日：2004-11-17

    Applicant: SCIMED LIFE SYSTEMS, INC.

    Inventor： EIDENSCHINK, Tracee

    IPC: A61F2/06

    CPC classification number: A61F2/856 ,  A61F2/954 ,  A61F2/958 ,  A61F2210/008 ,  A61F2250/0003 ,  A61M2025/0058 ,  A61M2025/1015 ,  A61M2025/1056

    Abstract: A catheter assembly comprises a catheter shaft (12, 14), a balloon (16) and a pair of collars (30, 32). The collars may be fixed or rotatable about a catheter shaft prior to exposure to an electric current. Where the collars are fixed to the shaft, the balloon is rotatable about the collars. When exposed to the electric current the collars expand to engage the waists of the balloon thereby sealing the balloon. Where the collars are rotatable about the shaft, the each waist of the balloon is engaged to a respective collars. When the rotatable collars are exposed to the electric current the collars expand to engage the shaft of the catheter thereby sealing the balloon.

    Abstract translation: 导管组件包括导管轴（12,14），气囊（16）和一对凸环（30,32）。 在暴露于电流之前，套环可以围绕导管轴固定或旋转。 在套环固定到轴上的情况下，气球可围绕轴环旋转。 当暴露于电流时，套环膨胀以接合气球的腰部，从而密封气球。 在套环可围绕轴旋转的情况下，球囊的每个腰部接合到相应的套环。 当可旋转的套环暴露于电流时，套环膨胀以接合导管的轴，从而密封气球。

    ADAPTIVE INTRAOCULAR LENS
    7.
    发明申请
    ADAPTIVE INTRAOCULAR LENS 审中-公开
    自适应眼科镜片

    公开(公告)号：WO2012067994A2

    公开(公告)日：2012-05-24

    申请号：PCT/US2011/060556

    申请日：2011-11-14

    Applicant: ELENZA, INC. ,  BLUM, Ronald David ,  MAZZOCCHI, Rudy

    Inventor： BLUM, Ronald David ,  MAZZOCCHI, Rudy

    IPC: A61F2/14

    CPC classification number: A61F2/1624 ,  A61F2/1613 ,  A61F2/1627 ,  A61F2/1635 ,  A61F2/1648 ,  A61F2210/008 ,  A61F2210/009

    Abstract: An implantable ophthalmic device with flexible, fluid-filled membranes provide dynamically variable optical power to restore lost accommodation in individuals suffering from presbyopia or aphakia without moving parts or reducing the amount of transmitted light. Actuating the device causes the fluid-filled membrane to change curvature, which produces a corresponding change in optical power. For instance, squeezing the edge of the membrane causes the center of the membrane to bulge by an amount proportional to the squeezing force. Alternatively, heating or applying a voltage to the membrane may cause the liquid in the membrane to undergo a phase transition accompanied by a corresponding change in volume that causes the membrane to inflate so as to change the optical power of the device.

    Abstract translation: 具有柔性流体填充膜的可植入眼科装置提供动态可变的光学功率，以恢复患有老花眼或无晶状体的个体的失去的适应性，而无需移动部件或减少透射光量。 驱动该装置导致流体填充的膜改变曲率，这产生相应的光功率变化。 例如，挤压膜的边缘导致膜的中心膨胀与挤压力成比例的量。 或者，加热或向膜施加电压可能导致膜中的液体经历伴随相应体积变化的相变，导致膜膨胀以改变装置的光功率。

    ADJUSTABLE OPTICAL ELEMENT WITH MULTIZONE POLYMERIZATION
    9.
    发明申请
    ADJUSTABLE OPTICAL ELEMENT WITH MULTIZONE POLYMERIZATION 审中-公开
    可调整的光学元件与多光子聚合

    公开(公告)号：WO2006096193A2

    公开(公告)日：2006-09-14

    申请号：PCT/US2005/020699

    申请日：2005-06-09

    Applicant: MINU LLC ,  PEYMAN, Gholam, A.

    Inventor： PEYMAN, Gholam, A.

    IPC: A61B18/18 ,  A61F2/16 ,  A61B17/20 ,  A61N1/30

    CPC classification number: A61F2/147 ,  A61F2210/008 ,  A61F2250/0001 ,  A61F2250/0048 ,  A61L27/16

    Abstract: The present invention relates to an optical element for correcting refractive error in an eye. The optical element includes a first portion having a first volume that remains substantially constant when exposed to an energy, and a second portion having a second volume that is adapted to change when exposed to the energy. This optical element results in a device that can correct severe ametropic conditions, without ablating any portion of the element itself or the cornea.

    Abstract translation: 本发明涉及一种用于校正眼睛屈光不正的光学元件。 光学元件包括第一部分，其具有当暴露于能量时保持基本恒定的第一体积，以及具有适于在暴露于能量时改变的第二体积的第二部分。 该光学元件产生可以校正严重的变态条件而不消除元件本身或角膜的任何部分的装置。

    ARTIFICIAL NUCLEUS PULPOSUS AND METHOD OF INJECTING SAME
    10.
    发明申请
    ARTIFICIAL NUCLEUS PULPOSUS AND METHOD OF INJECTING SAME 审中-公开
    人造髓核及其注射方法

    公开(公告)号：WO2004064673A9

    公开(公告)日：2004-09-10

    申请号：PCT/US2004001321

    申请日：2004-01-16

    Applicant: PSINERGI CORP ,  DULAK GARY R ,  BHALANI ANIL ,  MOLLOY PAUL A

    Inventor： DULAK GARY R ,  BHALANI ANIL ,  MOLLOY PAUL A

    IPC: A61B17/00 ,  A61F20060101 ,  A61F2/00 ,  A61F2/30 ,  A61F2/44 ,  A61F2/46 ,  A61L27/26 ,  A61F

    CPC classification number: A61F2/4611 ,  A61B17/00234 ,  A61F2/441 ,  A61F2/4601 ,  A61F2002/30088 ,  A61F2002/30583 ,  A61F2002/444 ,  A61F2002/4635 ,  A61F2210/008 ,  A61F2210/0085 ,  A61L27/26

    Abstract: The present invention relates to an artificial nucleus pulposus implant that is injected minimally invasively into the nucleus cavity of the annulus fibrosus to restore the normal anatomical and physiological function of the spine in the affected disc segment. In one aspect of the invention, a device is disclosed for delivering a phase changing biomaterial to a tissue site, the device comprising a dispenser including (i) a plunger having a proximal portion and a distal portion, an inlet end and an outlet end, (ii) a dispensing actuator attached to the proximal portion of the plunger, and (iii) a cartridge adapted to be inserted into the inlet end of the plunger for containing the phase changing biomaterial in a fluid state. The dispenser may be mechanically, pneumatically or hydraulically actuated. The dispenser may further comprise a nozzle attached to the cartridge for dispensing the biomaterial to the tissue site. In another aspect, the device may further comprise a tissue cavity access unit providing a conduit having an inlet end in fluid communication with the nozzle, and an outlet end adapted to deliver the biomaterial to the tissue site. The biomaterial may transition from the fluid state to a solid state after a set amount of time, a temperature change or an exposure to an external stimuli such as radiation, UV light or an electrical stimuli. The cartridge may be a dual-chambered cartridge for storing different fluid biomaterials in the two chambers. In another aspect of the invention, a process for producing the artificial nucleus pulposus implant in the nucleus cavity of the annulus fibrosus is disclosed, the process comprising the steps of (a) obtaining access to the nucleus cavity; (b) injecting the artificial nucleus pulposus into the nucleus cavity; and (c) permitting the biomaterial to transition from a fluid state to a solid state in-situ after a given condition.

    Abstract translation: 本发明涉及人造髓核植入物，其被微创地侵入到纤维环的髓核腔中，以恢复受影响的椎间盘节段中脊柱的正常解剖和生理功能。 在本发明的一个方面中，公开了一种用于将相变生物材料递送至组织部位的装置，该装置包括分配器，该分配器包括（i）具有近端部分和远端部分，入口端和出口端的柱塞， （ii）连接到柱塞的近侧部分的分配致动器，以及（iii）适于插入柱塞的入口端以用于容纳处于流体状态的相变生物材料的筒。 分配器可以机械地，气动地或液压地致动。 分配器可进一步包括附接到药筒的喷嘴，用于将生物材料分配到组织部位。 在另一方面，该装置可进一步包括组织空腔通路单元，其提供具有与喷嘴流体连通的入口端和适于将生物材料递送至组织部位的出口端的导管。 在设定的时间量，温度变化或暴露于诸如辐射，UV光或电刺激的外部刺激之后，生物材料可以从流体状态转变为固态。 盒可以是用于在两个腔室中存储不同的流体生物材料的双腔盒。 在本发明的另一方面中，公开了一种用于在纤维环的髓核中产生人造髓核植入物的方法，该方法包括以下步骤：（a）进入髓核腔; （b）将人造髓核注入髓核腔; 和（c）允许生物材料在给定条件后原位从流体状态过渡到固态。

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