公开(公告)号：WO2022226280A1

公开(公告)日：2022-10-27

申请号：PCT/US2022/025904

申请日：2022-04-22

申请人： DUKE UNIVERSITY ,  METABOLOMICS LABORATORY, BAKER HEART & DIABETE INSTITUTE ,  UNIVERSITY OF TEXAS HEALTH CENTER AT SAN ANTONIO ,  INDIANA ALZHEIMER DISEASE CENTER AND DEPT. OF RADIOLOGY AND IMAGINING SCIENCES ,  SUNY DOWNSTATE MEDICAL CENTER ,  INSTITUTE FOR SYSTEMS BIOLOGY ,  HELMHOLTZ ZENTRUM MUNCHEN- GERMAN RESEARCH CENTER FOR ENVIRONMENTAL HEALTH

发明人： KADDURAH-DAOUK, Rima, F. ,  LOUIE, Gregory ,  ARNOLD, Matthias ,  BAILLIE, Rebecca, A. ,  HAN, Xianlin ,  SAYKIN, Andrew, J. ,  NHO, Kwangsik ,  MORENO, Herman, W. ,  FUNK, Cory ,  BALONI, Priyanka ,  KASTENMUELLER, Gabi ,  MEIKLE, Peter

IPC分类号： G01N33/48 ,  C12Q1/68 ,  G01J3/00 ,  G01N33/50 ,  G01N33/52 ,  G01N33/567

摘要： Described herein are compositions and methods for assessing and modulating ceramide and sphingomyelin in neurological disorders.