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公开(公告)号：WO2023086478A1
公开(公告)日：2023-05-19
申请号：PCT/US2022/049552
申请日：2022-11-10
摘要： The present disclosure is directed toward measurement systems capable of optical analysis of a test sample. Embodiments in accordance with the present disclosure include a sample holder having a plurality of projections that extend from a planar surface, where the projections and planar surface collectively define an open sample-collection surface that enables an interrogation signal direct access to the test sample. The projections can be dimensioned and arranged to collectively define a geometric anti-reflection surface that is substantially non-reflective for the interrogation signal even at large angles of incidence. In some embodiments, the sample holder is configured as a reflective element that enables multiple passes of the interrogation signal through the test sample. In some embodiments, the sample holder is configured as a transmissive element. In some embodiments, the projections themselves are reflective.
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公开(公告)号：WO2023049384A1
公开(公告)日：2023-03-30
申请号：PCT/US2022/044588
申请日：2022-09-23
申请人： IHNS, Jurgen
发明人： IHNS, Jurgen
摘要： An apparatus (100) for assisting diagnosis of a dermatological phenomenon (12) includes a variable wavelength light source (110). A camera (120) captures images of the dermatological phenomenon (12). A computer (130) controls the variable wavelength light source (110) and the camera (120). The computer (130) is programmed to: cause the light source (110) to illuminate the dermatological phenomenon with different wavelengths each at different times; capture an image of the dermatological phenomenon illuminated with each of the different wavelengths to generate a set of images (140); execute a neural network that has been trained with images of dermatological phenomena types with the set of images (140) to generate a probability that the set of images (140) corresponds to a selected phenomenon type; and indicate the probability that the dermatological phenomenon (12) corresponds to at least one of dermatological phenomena types.
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公开(公告)号：WO2022257139A1
公开(公告)日：2022-12-15
申请号：PCT/CN2021/099838
申请日：2021-06-11
申请人： 深圳市大疆创新科技有限公司
IPC分类号： G01J3/00
摘要： 本申请实施例提供了一种植物状态确定方法，包括：获取植物对应的第一高光谱图像；从所述第一高光谱图像中提取目标波段对应的图像数据，以生成第二高光谱图像；根据所述第二高光谱图像，确定所述植物的状态信息。本申请实施例提供的方法，可以快速、准确的确定出植物的状态信息。
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公开(公告)号：WO2022226280A1
公开(公告)日：2022-10-27
申请号：PCT/US2022/025904
申请日：2022-04-22
申请人： DUKE UNIVERSITY , METABOLOMICS LABORATORY, BAKER HEART & DIABETE INSTITUTE , UNIVERSITY OF TEXAS HEALTH CENTER AT SAN ANTONIO , INDIANA ALZHEIMER DISEASE CENTER AND DEPT. OF RADIOLOGY AND IMAGINING SCIENCES , SUNY DOWNSTATE MEDICAL CENTER , INSTITUTE FOR SYSTEMS BIOLOGY , HELMHOLTZ ZENTRUM MUNCHEN- GERMAN RESEARCH CENTER FOR ENVIRONMENTAL HEALTH
发明人： KADDURAH-DAOUK, Rima, F. , LOUIE, Gregory , ARNOLD, Matthias , BAILLIE, Rebecca, A. , HAN, Xianlin , SAYKIN, Andrew, J. , NHO, Kwangsik , MORENO, Herman, W. , FUNK, Cory , BALONI, Priyanka , KASTENMUELLER, Gabi , MEIKLE, Peter
摘要： Described herein are compositions and methods for assessing and modulating ceramide and sphingomyelin in neurological disorders.
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公开(公告)号：WO2022152714A1
公开(公告)日：2022-07-21
申请号：PCT/EP2022/050479
申请日：2022-01-12
发明人： PROF. UHL, Rainer
摘要： The present invention is directed to a microscope device comprising a microscope objective (1); one or more light sources; at least 3 dichroic beam splitters (5, 10, 16) and at least 2 cameras (4, 9) characterized in that the light generated by the light source interacts with the sample (3) thereby producing a sample beam wherein - a first image having a spectral range of light (A) is separated from the sample beam with a first dichroic beam splitter (5) and guided via reflection element (8) to the light detector (4) of the first camera (9), thereby resulting in residual image X - a second image having a spectral range of light (B) is separated from residual image X with a second dichroic beam splitter (10) and guided via reflection element (13) to light detector (4) of the first camera (9) thereby resulting in residual image Y - a third image having a spectral range of light (C) is separated from residual beam Y with a third dichroic beam splitter (16) and guided via reflection element (19, 20) to the light de-tector (4) of the second camera (17) thereby resulting in residual image D - guiding residual image D as forth spectral range of light via reflection element (18) to the light detector (4) of the second camera (17).
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公开(公告)号：WO2021123039A1
公开(公告)日：2021-06-24
申请号：PCT/EP2020/086852
申请日：2020-12-17
发明人： KOGER, Birgit
IPC分类号： B01L7/00 , G01J3/00 , G01N21/64 , B01L2200/143 , B01L2300/0627 , B01L2300/1816 , B01L2300/1822 , B01L3/5082 , B01L7/52 , G01N2021/6441 , G01N21/0332 , G01N21/6452 , G01N2201/0694 , G01N2201/1241
摘要： The present disclosure provides a real-time thermocycler, comprising: a well for storing a sample comprising a target and fluorescence molecules, a thermal unit for adjusting a temperature of the sample, an excitation unit for exciting the fluorescence molecules of the sample via radiation, a detection unit for detecting a fluorescence signal from the sample, and a controller for controlling the excitation unit to adjust an intensity of the excitation of the sample based on information about the target, such that the fluorescence signal is in a working range of the detection unit.
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公开(公告)号：WO2021084023A1
公开(公告)日：2021-05-06
申请号：PCT/EP2020/080434
申请日：2020-10-29
申请人： KINGS COLLEGE LONDON
摘要： An apparatus and method for determining at least one scattering coefficient of at least one section of at least one tooth, the apparatus comprising a patterned light generator system configured to generate at least one pattern of infrared light, a patterned light delivery system configured to deliver the at least one pattern of infrared light to the at least one section of the at least one tooth along a patterned light delivery axis, a polarising beam filtering system and a detection system configured to detect the at least one pattern of infrared light backscattered from the at least one section of the at least one tooth along a backscattered light detection axis, wherein the polarising beam filtering system is configured such that the patterned light delivery axis and the backscattered light detection axis are co-aligned onto the at least one section of the at least one tooth.
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公开(公告)号：WO2021047947A1
公开(公告)日：2021-03-18
申请号：PCT/EP2020/074312
申请日：2020-09-01
申请人： ETH ZURICH , UNIVERSITÄT ZÜRICH
发明人： CLAVIEN, Pierre-Alain , DUTKOWSKI, Philipp , HEFTI, Max , SCHULER, Martin , BECKER, Dustin , RUDOLF VON ROHR, Philipp
摘要： The invention relates to a method for evaluating damage of an organ tissue, in particular ischemic damage/injury of an organ tissue, with the steps of measuring the concentration of at least one marker molecule in the perfusate of the organ tissue, wherein the measured concentration of the at least one marker molecule in the perfusate is used in at least one computer based prediction algorithm for generating at least one success score, wherein the success score has been previously defined based on at least one parameter value of at least one pre-defined parameter; wherein the at least one parameter value is determined after a transplantation of the organ tissue; and wherein based on the at least one success score at least one signal and/or at least one set of data is generated for facilitating the decision, if the organ tissue is suitable for transplantation or not.
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9.发明申请
公开(公告)号：WO2020117460A1
公开(公告)日：2020-06-11
申请号：PCT/US2019/061961
申请日：2019-11-18
摘要： Described herein is a process for correcting an observed color difference between a color at a first gloss and the color at a second gloss different than the first gloss, said process comprising the steps of: (a) determining a first correction caused by a lightness (Y-value) of the color a first gloss; (b) determining a second correction caused by an inclusion of a first surface diffusion in gloss readings; (c) based on the first and second corrections, determining a specular correction caused by a difference in specular reflections from the color at the first gloss and the color at the second gloss; (d) determining tristimulus corrections based on the specular correction; (e) preparing corrected tristimulus values of the color at a second gloss; and (f) producing a paint composition for the color at the second gloss using the corrected tristimulus values.
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公开(公告)号：WO2020113183A1
公开(公告)日：2020-06-04
申请号：PCT/US2019/063877
申请日：2019-11-29
申请人： IN DIAGNOSTICS, INC.
发明人： FLORESCU, Octavian
摘要： The single-use disposable spectrophotometer described herein can measure one or more blood chemistry analytes from a drop of whole blood. A passive filtration system takes whole blood and delivers plasma along with a dissolved reporter molecule to one or more spectrophotometers which can operate with narrow band optical spectrum centered on an optical detection frequency. The spectrophotometer detects the changes in absorption of the plasma as a result of a chemistry reaction to determine the concentration or activity of one or more analytes.
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