INCREASED ETHANOL PRODUCTION IN RECOMBINANT BACTERIA
    6.
    发明申请
    INCREASED ETHANOL PRODUCTION IN RECOMBINANT BACTERIA 审中-公开
    在重组细菌中增加乙醇生产

    公开(公告)号:WO2010010116A1

    公开(公告)日:2010-01-28

    申请号:PCT/EP2009/059421

    申请日:2009-07-22

    IPC分类号: C12P7/06 C12N15/04 C12R1/01

    摘要: The invention pertains to a recombinant bacterium with enhanced ethanol production characteristics when cultivated in a growth medium comprising glycerol. The recombinant bacterium comprises an inserted heterologous gene encoding glycerol dehydrogenase, and/or an up-regulated native gene encoding glycerol dehydrogenase. Particularly there is provided the recombinant bacterium BG1G1 of the Thermoanaerobacter mathranii species with an inserted heterologous gene encoding the E.C. 1.1.1.6 type, a NAD dependent glycerol dehydrogenase obtained from Thermotoga maritima.

    摘要翻译: 本发明涉及当在包含甘油的生长培养基中培养时具有增强的乙醇生产特性的重组细菌。 重组细菌包含编码甘油脱氢酶的插入异源基因和/或编码甘油脱氢酶的上调天然基因。 特别提供了具有编码E.C.1.1.1.6型的插入的异源基因的Thermoanaerobacter mathranii物种的重组细菌BG1G1,从Thermotoga maritima获得的NAD依赖性甘油脱氢酶。