公开(公告)号：WO2006134467A1

公开(公告)日：2006-12-21

申请号：PCT/IB2006/001581

申请日：2006-06-06

Applicant: PFIZER INC. ,  DRESS, Klaus, Ruprecht ,  NAIR, Sajiv, Krishman ,  SIU, Michael ,  TAYLOR, Wendy, Dianne

Inventor： DRESS, Klaus, Ruprecht ,  NAIR, Sajiv, Krishman ,  SIU, Michael ,  TAYLOR, Wendy, Dianne

IPC: C07D417/12 ,  C07D213/75 ,  A61K31/4439 ,  A61P9/00

CPC classification number: C07D213/75 ,  C07D417/12

Abstract: The present invention relates to novel compounds, to pharmaceutical compositions comprising the compounds described herein, their pharmaceutically acceptable salts, hydrates and solvates, as well as to the use of the compounds in medicine and for the preparation of a medicament which acts on the human 11-β-hydroxysteroid dehydrogenase type 1 enzyme (11βHSD1).

Abstract translation: 本发明涉及新化合物，其包含本文所述的化合物，其药学上可接受的盐，水合物和溶剂合物的药物组合物，以及该化合物在医药中的用途以及用于制备作用于人11 -β-羟基类固醇脱氢酶1型酶（11βHSD1）。