DISPOSITIF D'AMPLIFICATION D'ADN OU ARN ET PROCEDE

    公开(公告)号:WO2022090880A1

    公开(公告)日:2022-05-05

    申请号:PCT/IB2021/059790

    申请日:2021-10-23

    Inventor: NAVARRO, Thierry

    Abstract: Dispositif d'amplification comprenant un compartiment de collecte relié à un compartiment de réaction par au moins un élément de liaison comprenant un mois un canal ou cavité, destiné à dupliquer en grand nombre une séquence d'ADN ou d'ARN d'un échantillon mélangé à une solution, dont une partie est transférée du compartiment de collecte vers le compartiment de réaction en actionnant l'élément de liaison de manière externe.

    A VOLUMETRIC PUMP COMPRISING A DRIVING MECHANISM
    2.
    发明申请
    A VOLUMETRIC PUMP COMPRISING A DRIVING MECHANISM 审中-公开
    包含驱动机构的体积泵

    公开(公告)号:WO2007141681A2

    公开(公告)日:2007-12-13

    申请号:PCT/IB2007051812

    申请日:2007-05-14

    Inventor: NAVARRO THIERRY

    CPC classification number: F04B7/0007 F04B9/047 F04B19/022

    Abstract: A volumetric pump comprises at least one piston (1) inside a cylindrical housing (2) and means to cause a relative to-and-fro linear movement between the cylindrical housing (2) and the piston (1) in order to produce a stroke of the volumetric pump. This pump further comprises a bi-directional angular rotatable disc (4) acting as a valve which connects alternately at least one inlet port and at least one outlet port (5, 5') to a least one pump chamber (6, 6') located inside the housing (2), and a driving mechanism arranged to dissociate at least partially the bi-directional angular movement of the rotatable disc (4) with the to-and-fro linear movement of the housing (2). This driving mechanism is arranged such that the rotatable disc (4) reaches an angular position at which it opens and/or closes the inlet and/or outlet ports (5, 5') when there is no relative to-and-fro linear movement between the cylindrical housing (2) and the piston (1).

    Abstract translation: 容积泵包括在圆柱形壳体(2)内部的至少一个活塞(1)和用于在圆柱形壳体(2)和活塞(1)之间引起相对的线性运动的装置,以产生冲程 的容积泵。 该泵还包括用作阀的双向角度可旋转盘(4),所述阀将至少一个入口端口和至少一个出口端口(5,5')交替连接至至少一个泵室(6,6'), 位于壳体(2)内部的驱动机构,以及驱动机构,其布置成使得壳体(2)的来回线性运动至少部分地解离旋转盘(4)的双向角运动。 该驱动机构被布置成使得当不存在相对来回的线性运动时,可旋转盘(4)到达其打开和/或关闭入口和/或出口(5,5')的角度位置 在圆柱形壳体(2)和活塞(1)之间。

    VOLUMETRIC PUMP
    3.
    发明申请
    VOLUMETRIC PUMP 审中-公开
    体积泵

    公开(公告)号:WO2008086349A1

    公开(公告)日:2008-07-17

    申请号:PCT/US2008/050506

    申请日:2008-01-08

    Abstract: In one embodiment, a volumetric pump in a medical fluid delivery system comprises at least one piston in a hollow cylinder, the pump having at least one inlet port through which a medical fluid can be sucked into a pump chamber during an instroke of said piston, and at least one outlet port through which the medical fluid can be expelled during an outstroke of the piston. The piston or the hollow cylinder can be actuated directly or indirectly by a rotor. This rotor transmits on the one hand a bi-directional linear movement to the piston or to the cylinder and on the other hand, a bi-directional angular movement either to the piston or to another rotable element in order to open and close alternately the inlet and outlet ports.

    Abstract translation: 在一个实施例中,医用流体输送系统中的容积泵包括中空圆柱体中的至少一个活塞,所述泵具有至少一个入口,在所述活塞发生期间,医用流体可以通过该吸入口吸入泵室中, 以及至少一个出口,在活塞的行程过程中医药流体可以通过该出口排出。 活塞或中空圆柱体可以由转子直接或间接地致动。 该转子一方面传递到活塞或缸体的双向线性运动,另一方面传递到活塞或另一可旋转元件的双向角运动,以便交替地打开和关闭入口 和出口端口。

    DISPOSITIF THERMORÉGULÉ DESTINÉ À MODIFIER LA CONSISTANCE D'UNE COMPOSITION ET PROCÉDÉ DE MISE EN OEUVRE DU DISPOSITIF
    5.
    发明申请
    DISPOSITIF THERMORÉGULÉ DESTINÉ À MODIFIER LA CONSISTANCE D'UNE COMPOSITION ET PROCÉDÉ DE MISE EN OEUVRE DU DISPOSITIF 审中-公开
    用于修饰组合物一致性的热调节装置和操作装置的方法

    公开(公告)号:WO2015121736A2

    公开(公告)日:2015-08-20

    申请号:PCT/IB2015/000138

    申请日:2015-02-11

    Abstract: L'invention se rapporte à un dispositif thermorégulé destiné à modifier la consistance d'une composition de départ comportant une préparation au moins partiellement mélangée à un liquide. Le dispositif est configuré pour recevoir à cet effet un réservoir (3; 203; 303; 403; 503; 603; 703) contenant la composition de départ, et possédant deux faces opposées dont au moins une face comprend une partie souple, le dispositif comportant un élément thermorégulé (2; 202; 302; 402) présentant une surface de contact prédéfinie agencée pour venir en contact avec l'une des faces opposées du réservoir (3; 203; 303; 403; 503), ainsi que des moyens de brassage pour malaxer la composition du réservoir (3; 203; 303; 403). Ces moyens de brassage comportent un mélangeur (10; 210; 310; 410) ainsi que des moyens d'entraînement (30; 230; 330) agencés pour amener le mélangeur (10; 210; 310; 410) en appui sur ladite partie souple du réservoir (3; 203; 303; 403; 503), lorsque celui-ci est disposé sur l'élément thermorégulé (2; 202; 302; 402) du dispositif, de sorte à créer une zone de compression locale (8; 208; 308) à l'intérieur du réservoir (3; 203; 303; 403; 503). Les moyens d'entraînement (30; 230; 330) sont en outre agencés pour ensuite déplacer le mélangeur (10; 210; 310; 410) par rapport à la partie souple du réservoir (3; 203; 303; 403; 503) afin de déplacer ladite zone de compression locale (8; 208; 308) à l'intérieur du réservoir (3; 203; 303; 403; 503) de manière à malaxer la composition du réservoir (3; 203; 303; 403; 503) au cours de l'opération de malaxage.

    Abstract translation: 本发明涉及一种用于改变起始组合物的稠度的调节装置,其包含至少部分地与液体混合的制剂。 为此目的,该装置构造成容纳包含起始组合物并具有两个相对面的贮存器(3; 203; 303; 403; 503; 603; 703),其中至少一个包括柔性部分,该装置包括 具有布置成与所述储存器(3; 203; 303; 403; 503)中的一个相对面接触的预定接触表面的调温元件(2; 202; 302; 402)以及用于混合的搅拌装置 储存器(3; 203; 303; 403)中的组成。 搅拌装置包括混合器(10; 210; 310; 410)以及驱动装置(30; 230; 330),驱动装置(30; 230; 330)被布置成用于使所述容器的所述柔性部分上的混合器(10; 210; 当储存器设置在装置的调温元件(2; 202; 302; 402)上时,以使得产生局部压缩区(8; 208; 503; 403; 403; 503) 308)在储存器(3; 203; 303; 403; 503)的内部。 驱动装置(30; 230; 330)也布置成相对于储存器(3; 203; 303; 403; 503)的柔性部分移动混合器(10; 210; 310; 410),以便 将所述局部压缩区(8; 208; 308)置于储存器(3; 203; 303; 403; 503)的内部,以便将储存器(3; 203; 303; 403; 403; 503)。

    FLUID DELIVERY SYSTEM COMPRISING A FLUID PUMPING DEVICE AND A DRIVE SYSTEM
    6.
    发明申请
    FLUID DELIVERY SYSTEM COMPRISING A FLUID PUMPING DEVICE AND A DRIVE SYSTEM 审中-公开
    包含流体泵装置和驱动系统的流体输送系统

    公开(公告)号:WO2011010198A3

    公开(公告)日:2011-12-08

    申请号:PCT/IB2010001683

    申请日:2010-07-06

    Abstract: A fluid pumping device comprising a pump housing (1; 101; 201; 301; 701; 901) containing a piston chamber (11; 101 '; 201 '; 310a, 301b; 701 '; 901 ' ) and a piston (2; 102; 202; 302, 302 '; 702; 902, 902 " ) moving back and forth inside the piston chamber, an inlet port (10i; 110i; 210i; 310i; 710i; 921) and an outlet port (10o; 110?; 210o; 310o; 710o; 920) allowing a fluid to be sucked into the piston chamber during an instroke of the piston and expelled from the piston chamber during an outstroke. The device further comprises a valve - switching element (9; 109; 201; 309; 701; 909 ) movably mounted against a valve base member (7; 107; 207; 307; 707; 907), which comprises a piston chamber aperture (12p; 112p; 212p; 312p, 312p 1; 712p; 912p) connected to the piston chamber and an inlet aperture (12i; 112i; 212i;312i;712i;912i) and an outlet aperture (12o; 112o; 212o; 312o; 712o; 912o) connected respectively to the inlet and outlet ports of the fluid pumping device. The element comprises a groove (14; 114; 214; 314, 314 '; 714; 914) or other recess (514) moving against the valve base member such that, a first communication allows leakage between the inlet aperture and the piston chamber aperture so that fluid is sucked from the inlet port, through the groove or recess, into the piston chamber during part of the piston instroke, while a second communication allows leakage between the piston chamber aperture and the outlet aperture expelling fluid out of the piston chamber, through the groove or recess and the outlet port during part of the piston outstroke.

    Abstract translation: 一种液体泵送装置,包括容纳活塞室(11; 101'; 201'; 310a,301b; 701'; 901')的泵壳体(1; 101; 201; 301; 701; 901) 102; 202; 302,302'; 702; 902,902“),在所述活塞室内前后移动,入口端口(10i; 110i; 210i; 310i; 710i; 921)和出口端口 ; 210o; 310o; 710o; 920),允许在活塞发生期间将流体吸入活塞室,并且在行程过程中从活塞室排出,该装置还包括阀开关元件(9; 109; 201 其包括活塞室孔径(12p; 112p; 212p; 312p,312p1; 712p; 912p),其可移动地安装在阀底部构件(7; 107; 207; 307; 707; 907) 连接到活塞室和分别连接到流体的入口和出口的入口孔(12i; 112i; 212i; 312i; 712i; 912i)和出口孔(12o; 112o; 212o; 312o; 712o; 912o) 抽水装置 凹槽(14; 114; 214; 314,314'; 714; 914)或其他凹部(514),其抵靠阀底部构件移动,使得第一通信允许入口孔和活塞室孔之间的泄漏,使得流体从入口通过槽或凹槽被吸入活塞 在第二通信过程中,在活塞行程的一部分期间,第二通信允许活塞室孔和出口孔之间的泄漏通过槽或凹部和出口端口排出活塞室。

    FLUID DELIVERY SYSTEM COMPRISING A FLUID PUMPING DEVICE AND A DRIVE SYSTEM
    7.
    发明申请
    FLUID DELIVERY SYSTEM COMPRISING A FLUID PUMPING DEVICE AND A DRIVE SYSTEM 审中-公开
    包含流体泵装置和驱动系统的流体输送系统

    公开(公告)号:WO2011010198A2

    公开(公告)日:2011-01-27

    申请号:PCT/IB2010/001683

    申请日:2010-07-06

    Abstract: There is described a fluid pumping device comprising a pump housing (1; 101; 201; 301; 701; 901 ) containing at least one piston chamber (11; 101 '; 201 '; 310a, 301 b; 701 '; 901') and at least one piston (2; 102; 202; 302, 302'; 702; 902, 902") arranged to move back and forth inside the piston chamber, at least one inlet port (10i; 110i; 210i; 310i; 710i; 921 ) and at least one outlet port (10o; 110o; 210o; 310o; 710o; 920) arranged so that a fluid can be sucked through the inlet port into the piston chamber during an instroke of the piston and expelled from the piston chamber through the outlet port during an outstroke of the piston. The fluid pumping device further comprises a valve-switching element (9; 109; 201; 309; 701; 909) that is movably mounted against a valve base member (7; 107; 207; 307; 707; 907), said valve base member comprising at least one piston chamber aperture (12p; 112p; 212p; 312p, 312p'; 712p; 912p) connected to the piston chamber and at least one inlet aperture (12i; 112i; 212i; 312i; 712i; 912i) and at least one outlet aperture (12o; 112o; 212o; 312o; 712o; 912o) connected respectively to the inlet and outlet ports of the fluid pumping device. The valve-switching element comprises at least one groove (14; 114; 214; 314, 314'; 714; 914) or other recess (514) arranged to move against the valve base member such that, said groove or recess creates a first communication allowing leakage between the inlet aperture and the piston chamber aperture so that fluid is sucked from the inlet port, through the groove or recess, into the piston chamber during at least a part of the piston instroke, while said groove or recess creates a second communication allowing leakage between the piston chamber aperture and the outlet aperture so that fluid is expelled out of the piston chamber, through the groove or recess and the outlet port during at least a part of the piston outstroke.

    Abstract translation: 描述了一种流体泵送装置,其包括容纳至少一个活塞室(11; 101'; 201'; 310a,301b; 701'; 901')的泵壳体(1; 101; 201; 301; 701; 901) 以及至少一个活塞(2; 102; 202; 302,302'; 702; 902,902“),其被布置成在所述活塞室内前后移动,至少一个入口端口(10i; 110i; 210i; 310i; 710i ; 921)和至少一个出口端口(100; 110o; 210o; 310o; 710o; 920),其布置成使得流体能够在所述活塞触发期间通过所述入口吸入所述活塞室中并从所述活塞室排出 所述流体泵送装置还包括阀开关元件(9; 109; 201; 309; 701; 909),所述阀开关元件可移动地安装在阀基部件(7; 107; 207)上 ; 307; 707; 907),所述阀底部构件包括连接到活塞室的至少一个活塞室孔(12p; 112p; 212p; 312p,312p'; 712p; 912p)和至少一个入口孔 re(12i; 112 1; 212 1; 312I; 712i; 912i)和分别连接到流体泵送装置的入口和出口的至少一个出口孔(12o; 112o; 212o; 312o; 712o; 912o)。 阀切换元件包括至少一个凹槽(14; 114; 214; 314,314'; 714; 914)或其他凹槽(514),其布置成抵靠阀底座元件移动,使得所述凹槽或凹槽产生第一 通信允许入口孔和活塞室孔之间的泄漏,使得流体在活塞启动的至少一部分期间从入口通过凹槽吸入活塞室,而所述凹槽或凹槽产生第二 通信允许在活塞室孔和出口孔之间泄漏,使得流体在活塞行程的至少一部分期间通过凹槽或凹部和出口排出活塞室。

    A VOLUMETRIC PUMP COMPRISING A DRIVING MECHANISM

    公开(公告)号:WO2007141681A3

    公开(公告)日:2007-12-13

    申请号:PCT/IB2007/051812

    申请日:2007-05-14

    Inventor: NAVARRO, Thierry

    Abstract: A volumetric pump comprises at least one piston (1) inside a cylindrical housing (2) and means to cause a relative to-and-fro linear movement between the cylindrical housing (2) and the piston (1) in order to produce a stroke of the volumetric pump. This pump further comprises a bi-directional angular rotatable disc (4) acting as a valve which connects alternately at least one inlet port and at least one outlet port (5, 5') to a least one pump chamber (6, 6') located inside the housing (2), and a driving mechanism arranged to dissociate at least partially the bi-directional angular movement of the rotatable disc (4) with the to-and-fro linear movement of the housing (2). This driving mechanism is arranged such that the rotatable disc (4) reaches an angular position at which it opens and/or closes the inlet and/or outlet ports (5, 5') when there is no relative to-and-fro linear movement between the cylindrical housing (2) and the piston (1).

    VOLUMETRIC PUMP WITH RECIPROCATED AND ROTATED PISTON
    9.
    发明申请
    VOLUMETRIC PUMP WITH RECIPROCATED AND ROTATED PISTON 审中-公开
    具有旋转和旋转活塞的体积泵

    公开(公告)号:WO2006056828A1

    公开(公告)日:2006-06-01

    申请号:PCT/IB2005/002423

    申请日:2005-08-12

    Inventor: NAVARRO, Thierry

    CPC classification number: F04B19/022 F04B7/06 F04B9/02 F04B9/04

    Abstract: A volumetric pump (1) comprising at least one piston (2) in a hollow cylinder (3), said pump (1) having at least one inlet port (10) through which a liquid (15) can be sucked into a pump chamber (3) during an instroke of said piston (2), and at least one outlet port (11) through which the liquid (15) can be expelled during an outstroke of the piston (2). Said piston (2) or the hollow cylinder (3) of the volumetric pump (1) can be actuated directly or indirectly by at least one rotor (5). This rotor (5) transmits, on the one hand a bi-directional linear movement to the piston (2) or to the cylinder (3) causing said piston (2) to slide back and forth inside said cylinder (3) or following the axis of said piston (2), and on the other hand, a bi-directional angular movement either to the piston (2) or to a disc (24) in order to open and close alternately the inlet and outlet ports (10, 11).

    Abstract translation: 一种在中空圆筒(3)中包括至少一个活塞(2)的容积泵(1),所述泵(1)具有至少一个入口(10),液体(15)可以通过所述入口端口吸入泵室 (3)在所述活塞(2)的冲程期间,以及至少一个出口(11),所述液体(15)在所述活塞(2)的行程过程中可被排出。 容积泵(1)的所述活塞(2)或中空圆筒(3)可以由至少一个转子(5)直接或间接地致动。 该转子(5)一方面向活塞(2)或气缸(3)传递双向直线运动,使所述活塞(2)在所述气缸(3)内前后滑动 所述活塞(2)的轴线,另一方面是活塞(2)或盘(24)的双向角运动,以便交替地打开和关闭入口和出口(10,11 )。

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