PROCESSES FOR THE PRODUCTION OF 2-ISOCEPHEM DERIVATIVES
    1.
    发明申请
    PROCESSES FOR THE PRODUCTION OF 2-ISOCEPHEM DERIVATIVES 审中-公开
    生产2-异构体衍生物的方法

    公开(公告)号:WO1996028453A1

    公开(公告)日:1996-09-19

    申请号:PCT/JP1996000538

    申请日:1996-03-06

    CPC classification number: C07D205/08 C07D501/00 Y02P20/55

    Abstract: A process for producing a 2-isocephem derivative which comprises treating, in a water-containing organic solvent, a 2-azetidinyl-3,4-dihalogeno-2-butenoic acid compound represented by general formula (1) with a thioacetic acid derivative showing basicity per se or a mixture of a base with a thioacetic acid derivative to thereby give a 3-halomethyl-2-isocephem derivative represented by general formula (2); and a process for producing a 2-oxaisocephem derivative which comprises treating, in a water-containing organic solvent, a 2-azetidinyl-3,4-dihalogeno-2-butenoic acid compound represented by general formula (1) with a base to thereby give a 3-halomethyl-2-oxaisocephem derivative represented by general formula (3); in formula (1), R represents hydrogen or optionally protected amino; R represents hydrogen or lower alkoxy, or R and R may form together a cyclic amino protecting group; R represents hydrogen or a carboxyl protecting group; W represents a leaving group; and X and Y may be the same or different and each represents halogeno; in formula (2), R , R , R and X are each as defined above; in formula (3), R , R , R and X are each as defined above.

    Abstract translation: 一种2-异头孢烯衍生物的制造方法,其特征在于,在含水有机溶剂中,将由通式(1)表示的2-氮杂环丁烷基-3,4-二卤代-2-丁烯酸化合物与硫代乙酸衍生物 碱性本身或碱与硫代乙酸衍生物的混合物,从而得到由通式(2)表示的3-卤代甲基-2-异头孢烯衍生物; 以及2-氧代硫代衍生物的制造方法,其包括在含水有机溶剂中用碱处理由通式(1)表示的2-氮杂环丁烷基-3,4-二卤代-2-丁烯酸化合物,由此 得到由通式(3)表示的3-卤甲基-2-氧代硫代头孢烯衍生物; 在式(1)中,R 1表示氢或任选保护的氨基; R 2表示氢或低级烷氧基,或者R 1和R 2可以一起形成环状氨基保护基; R 3表示氢或羧基保护基; W代表离去组; X和Y可以相同或不同,各自表示卤素; 在式(2)中,R 1,R 2,R 3和X各自如上所定义; 在式(3)中,R 1,R 2,R 3和X各自如上所定义。

    PROCESS FOR PRODUCING DIAZOMETHANE DERIVATIVE
    3.
    发明申请
    PROCESS FOR PRODUCING DIAZOMETHANE DERIVATIVE 审中-公开
    生产二唑衍生物的方法

    公开(公告)号:WO1995016666A1

    公开(公告)日:1995-06-22

    申请号:PCT/JP1994002124

    申请日:1994-12-16

    CPC classification number: C07C245/14

    Abstract: A process for producing a diazomethane derivative by oxidizing a hydrazone derivative in a two-phase system containing: a) an aqueous solution of a mixture of a caustic alkali and an alkali metal hypochlorite in respective concentrations of 4-14 w/w % and 3-10 w/w % based on the total weight of the solution; b) a hydrophobic organic solvent; c) an inorganic iodine compound, and d) a phase-transfer catalyst.

    Abstract translation: 通过在两相体系中氧化腙衍生物来制备重氮甲烷衍生物的方法,其包含:a)苛性碱和碱金属次氯酸盐的混合物的水溶液,其浓度分别为4-14w / w%和3 -10w / w%,基于溶液的总重量; b)疏水性有机溶剂; c)无机碘化合物,和d)相转移催化剂。

    BENZOSELENAZOLINE-SPIRO-VINYLPYRAN COMPOUND AND POLYMER COMPRISING THE SAME
    8.
    发明申请
    BENZOSELENAZOLINE-SPIRO-VINYLPYRAN COMPOUND AND POLYMER COMPRISING THE SAME 审中-公开
    苯并咪唑啉 - 螺环 - 乙烯基化合物和包含其的聚合物

    公开(公告)号:WO1991013072A1

    公开(公告)日:1991-09-05

    申请号:PCT/JP1991000202

    申请日:1991-02-18

    CPC classification number: C07D517/10 G03C1/685

    Abstract: A photochromic compound of general formula (Ia), wherein R1 represents C¿1? to C20 alkyl or aralkyl; R?2 to R5¿ each represents hydrogen, C¿1? to C6 alkyl, aryl, aralkyl, C1 to C5 alkoxy, halogeno, cyano, trichloromethyl, trifluoromethyl or nitro; R?6 and R7¿ each represents hydrogen, C¿1?-C6 alkyl, aryl, aralkyl, halogeno, cyano or nitro; and X represents oxygen or sulfur; a homopolymer of said compound; and a copolymer thereof with a vinylic compound of the general formula: CH2=CYZ, wherein Y represents H or CH3, and Z represents carboxyl, alkoxycarbonyl, cyano, carbamoyl, N,N-dimethylcarbamoyl, acetoxy, phenyl or methylphenyl.

    SECONDARY LITHIUM BATTERY
    9.
    发明申请
    SECONDARY LITHIUM BATTERY 审中-公开
    二次锂电池

    公开(公告)号:WO1990010316A1

    公开(公告)日:1990-09-07

    申请号:PCT/JP1990000209

    申请日:1990-02-21

    CPC classification number: H01M10/052 C08G79/025 H01M10/0565

    Abstract: This invention provides a secondary lithium battery comprising layered vanadium penta-oxide as a positive electrode active material (1), a substance which can occlude and release lithium ions as a negative electrode active material (3), and a polymer represented by formula (I) containing a lithium salt dissolved therein as an electrolyte (2), wherein m is a real number having a value ranging from about 5 to 25, and n is a real number having a value in the following range: 3 « n « 200,000. This battery is characterized in that both of the electrode active materials have a high energy density, that the electrolyte is flame-retardant, nonflowable and safe, and that the battery can retain its characteristics even at a low environmental temperature below the ice point.

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