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公开(公告)号:WO2007092610A3
公开(公告)日:2008-05-08
申请号:PCT/US2007003542
申请日:2007-02-07
Applicant: TIVAMED INC , PARMER JONATHAN B
Inventor: PARMER JONATHAN B
IPC: A61N1/39
CPC classification number: A61B18/1485 , A61B18/1206 , A61B18/18 , A61B2018/00023 , A61B2018/00559 , A61B2018/00702 , A61B2018/00791 , A61B2018/00875 , A61N7/022
Abstract: This invention relates generally to apparatus and methods for tightening tissue of the female genitalia by heating targeted connective tissue with radiant energy, while cooling the mucosal epithelial surface over the target tissue to protect it from the heat. Embodiments include a treatment tip that comprises both an energy delivery element and a cooling mechanism. As the treatment tip contacts the epithelial mucosa, the tip cools the mucosa by contact, and delivers energy through the epithelium to the underlying tissue, thereby creating a reverse thermal gradient. The effect of the applied heat is to remodel genital tissue by tightening it. Such remodeling may include a tighter vagina and a tighter introitus. The tightening may be a consequence of thermal denaturation of collagen as well as a longer term healing response in the tissue that includes an increased deposition of collagen.
Abstract translation: 本发明一般涉及通过加热具有辐射能的靶向结缔组织,同时在目标组织上冷却粘膜上皮表面以保护其免受热量而使得女性生殖器的组织收紧的装置和方法。 实施例包括包括能量输送元件和冷却机构两者的处理尖端。 当治疗尖端接触上皮粘膜时,尖端通过接触来冷却粘膜,并将能量通过上皮传递到下面的组织,从而产生反向热梯度。 施加热量的作用是通过收紧生殖器组织来改造生物组织。 这种重塑可能包括更严格的阴道和更紧密的口腔。 紧固可能是胶原蛋白的热变性以及组织中长期愈合反应的结果,其包括胶原蛋白沉积增加。
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公开(公告)号:WO2011034986A3
公开(公告)日:2011-06-30
申请号:PCT/US2010049045
申请日:2010-09-16
Applicant: VIVEVE INC , PARMER JONATHAN B , SMITH IAN F , CHENG CHUN-CHIH , HOWE PATRICK KARL , SULLIVAN SEAN YASUO , JACKSON JEROME , LEVY STANLEY JR , LUCAS SHERREE LEIGH , LOPEZ STEVEN MARC
Inventor: PARMER JONATHAN B , SMITH IAN F , CHENG CHUN-CHIH , HOWE PATRICK KARL , SULLIVAN SEAN YASUO , JACKSON JEROME , LEVY STANLEY JR , LUCAS SHERREE LEIGH , LOPEZ STEVEN MARC
CPC classification number: A61B18/1485 , A61B18/1233 , A61B90/06 , A61B2017/00084 , A61B2018/00023 , A61B2018/00559 , A61B2018/00589 , A61B2018/00642 , A61B2018/00678 , A61B2018/00702 , A61B2018/00791 , A61B2018/00904 , A61B2018/0091 , A61B2090/065 , A61H19/00 , A61H21/00 , A61H23/0245 , A61H2201/0153 , A61H2201/0207 , A61H2201/0214 , A61H2201/0221 , A61H2201/0242 , A61H2201/0292 , A61H2201/10 , A61H2201/5038 , A61H2201/5097 , A61H2230/50 , A61H2230/65
Abstract: This invention relates generally to apparatus and methods for tightening tissue of the female genitalia by heating targeted connective tissue with radiant energy, while cooling the mucosal epithelial surface over the target tissue to protect it from the heat. Embodiments include a handle and treatment tip that has both an energy delivery element and a cooling mechanism. The handle may be a two-handed handle allowing control even while rotating and maneuvering the treatment around the genital opening. The apparatus or system may also include an integrated controller, which may confirm tissue contact without applying RF energy, based only on the temperature of the applicator and the time since the last application of energy from the applicator.
Abstract translation: 本发明一般涉及通过加热具有辐射能的靶向结缔组织,同时在目标组织上冷却粘膜上皮表面以保护其免受热量而使得女性生殖器的组织收紧的装置和方法。 实施例包括具有能量输送元件和冷却机构的手柄和处理尖端。 手柄可以是双手柄,即使在旋转和操纵生殖器开口周围的治疗的同时也能够进行控制。 该装置或系统还可以包括集成控制器,其可以仅基于施加器的温度和自上次施加来自施加器的能量以来的时间来确认组织接触而不施加RF能量。
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公开(公告)号:WO2011034986A2
公开(公告)日:2011-03-24
申请号:PCT/US2010/049045
申请日:2010-09-16
Applicant: VIVEVE, INC. , PARMER, Jonathan, B. , SMITH, Ian, F. , CHENG, Chun-Chih , HOWE, Patrick, Karl , SULLIVAN, Sean, Yasuo , JACKSON, Jerome , LEVY, Stanley, Jr. , LUCAS, Sherree, Leigh , LOPEZ, Steven, Marc
Inventor: PARMER, Jonathan, B. , SMITH, Ian, F. , CHENG, Chun-Chih , HOWE, Patrick, Karl , SULLIVAN, Sean, Yasuo , JACKSON, Jerome , LEVY, Stanley, Jr. , LUCAS, Sherree, Leigh , LOPEZ, Steven, Marc
CPC classification number: A61B18/1485 , A61B18/1233 , A61B90/06 , A61B2017/00084 , A61B2018/00023 , A61B2018/00559 , A61B2018/00589 , A61B2018/00642 , A61B2018/00678 , A61B2018/00702 , A61B2018/00791 , A61B2018/00904 , A61B2018/0091 , A61B2090/065 , A61H19/00 , A61H21/00 , A61H23/0245 , A61H2201/0153 , A61H2201/0207 , A61H2201/0214 , A61H2201/0221 , A61H2201/0242 , A61H2201/0292 , A61H2201/10 , A61H2201/5038 , A61H2201/5097 , A61H2230/50 , A61H2230/65
Abstract: This invention relates generally to apparatus and methods for tightening tissue of the female genitalia by heating targeted connective tissue with radiant energy, while cooling the mucosal epithelial surface over the target tissue to protect it from the heat. Embodiments include a handle and treatment tip that has both an energy delivery element and a cooling mechanism. The handle may be a two-handed handle allowing control even while rotating and maneuvering the treatment around the genital opening. The apparatus or system may also include an integrated controller, which may confirm tissue contact without applying RF energy, based only on the temperature of the applicator and the time since the last application of energy from the applicator.
Abstract translation: 本发明一般涉及用于通过加热具有辐射能量的靶向结缔组织来收紧女性生殖器的组织的装置和方法,同时冷却目标组织上的粘膜上皮表面以保护其免受热量。 实施例包括具有能量输送元件和冷却机构的手柄和处理尖端。 手柄可以是双手柄,即使在旋转和操纵生殖器开口周围的治疗时也可以进行控制。 该设备或系统还可以包括集成控制器,该集成控制器可以仅基于施用器的温度和自施加器最后一次施加能量以来的时间来确认组织接触而不施加RF能量。 p>
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公开(公告)号:WO2007092610A2
公开(公告)日:2007-08-16
申请号:PCT/US2007/003542
申请日:2007-02-07
Applicant: TIVAMED, INC. , PARMER, Jonathan, B.
Inventor: PARMER, Jonathan, B.
CPC classification number: A61B18/1485 , A61B18/1206 , A61B18/18 , A61B2018/00023 , A61B2018/00559 , A61B2018/00702 , A61B2018/00791 , A61B2018/00875 , A61N7/022
Abstract: This invention relates generally to apparatus and methods for tightening tissue of the female genitalia by heating targeted connective tissue with radiant energy, while cooling the mucosal epithelial surface over the target tissue to protect it from the heat. Embodiments include a treatment tip that comprises both an energy delivery element and a cooling mechanism. As the treatment tip contacts the epithelial mucosa, the tip cools the mucosa by contact, and delivers energy through the epithelium to the underlying tissue, thereby creating a reverse thermal gradient. The effect of the applied heat is to remodel genital tissue by tightening it. Such remodeling may include a tighter vagina and a tighter introitus. The tightening may be a consequence of thermal denaturation of collagen as well as a longer term healing response in the tissue that includes an increased deposition of collagen.
Abstract translation: 本发明一般涉及通过加热具有辐射能的靶向结缔组织,同时在目标组织上冷却粘膜上皮表面以保护其免受热量而使得女性生殖器的组织收紧的装置和方法。 实施例包括包括能量输送元件和冷却机构两者的处理尖端。 当治疗尖端接触上皮粘膜时,尖端通过接触来冷却粘膜,并将能量通过上皮传递到下面的组织,从而产生反向热梯度。 施加热量的作用是通过收紧生殖器组织来改造生物组织。 这种重塑可能包括更严格的阴道和更紧密的口腔。 紧固可能是胶原蛋白的热变性以及组织中长期愈合反应的结果,其包括胶原蛋白沉积增加。
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