公开(公告)号：WO2007092610A3

公开(公告)日：2008-05-08

申请号：PCT/US2007003542

申请日：2007-02-07

Applicant: TIVAMED INC ,  PARMER JONATHAN B

Inventor： PARMER JONATHAN B

IPC: A61N1/39

CPC classification number: A61B18/1485 ,  A61B18/1206 ,  A61B18/18 ,  A61B2018/00023 ,  A61B2018/00559 ,  A61B2018/00702 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61N7/022

Abstract: This invention relates generally to apparatus and methods for tightening tissue of the female genitalia by heating targeted connective tissue with radiant energy, while cooling the mucosal epithelial surface over the target tissue to protect it from the heat. Embodiments include a treatment tip that comprises both an energy delivery element and a cooling mechanism. As the treatment tip contacts the epithelial mucosa, the tip cools the mucosa by contact, and delivers energy through the epithelium to the underlying tissue, thereby creating a reverse thermal gradient. The effect of the applied heat is to remodel genital tissue by tightening it. Such remodeling may include a tighter vagina and a tighter introitus. The tightening may be a consequence of thermal denaturation of collagen as well as a longer term healing response in the tissue that includes an increased deposition of collagen.

Abstract translation: 本发明一般涉及通过加热具有辐射能的靶向结缔组织，同时在目标组织上冷却粘膜上皮表面以保护其免受热量而使得女性生殖器的组织收紧的装置和方法。 实施例包括包括能量输送元件和冷却机构两者的处理尖端。 当治疗尖端接触上皮粘膜时，尖端通过接触来冷却粘膜，并将能量通过上皮传递到下面的组织，从而产生反向热梯度。 施加热量的作用是通过收紧生殖器组织来改造生物组织。 这种重塑可能包括更严格的阴道和更紧密的口腔。 紧固可能是胶原蛋白的热变性以及组织中长期愈合反应的结果，其包括胶原蛋白沉积增加。

公开(公告)号：WO2007092610A2

公开(公告)日：2007-08-16

申请号：PCT/US2007/003542

申请日：2007-02-07

Applicant: TIVAMED, INC. ,  PARMER, Jonathan, B.

Inventor： PARMER, Jonathan, B.

CPC classification number: A61B18/1485 ,  A61B18/1206 ,  A61B18/18 ,  A61B2018/00023 ,  A61B2018/00559 ,  A61B2018/00702 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61N7/022

Abstract: This invention relates generally to apparatus and methods for tightening tissue of the female genitalia by heating targeted connective tissue with radiant energy, while cooling the mucosal epithelial surface over the target tissue to protect it from the heat. Embodiments include a treatment tip that comprises both an energy delivery element and a cooling mechanism. As the treatment tip contacts the epithelial mucosa, the tip cools the mucosa by contact, and delivers energy through the epithelium to the underlying tissue, thereby creating a reverse thermal gradient. The effect of the applied heat is to remodel genital tissue by tightening it. Such remodeling may include a tighter vagina and a tighter introitus. The tightening may be a consequence of thermal denaturation of collagen as well as a longer term healing response in the tissue that includes an increased deposition of collagen.

Abstract translation: 本发明一般涉及通过加热具有辐射能的靶向结缔组织，同时在目标组织上冷却粘膜上皮表面以保护其免受热量而使得女性生殖器的组织收紧的装置和方法。 实施例包括包括能量输送元件和冷却机构两者的处理尖端。 当治疗尖端接触上皮粘膜时，尖端通过接触来冷却粘膜，并将能量通过上皮传递到下面的组织，从而产生反向热梯度。 施加热量的作用是通过收紧生殖器组织来改造生物组织。 这种重塑可能包括更严格的阴道和更紧密的口腔。 紧固可能是胶原蛋白的热变性以及组织中长期愈合反应的结果，其包括胶原蛋白沉积增加。