公开(公告)号：WO2003023402A1

公开(公告)日：2003-03-20

申请号：PCT/SE2002/001635

申请日：2002-09-12

Applicant: OSCARSSON, Sven ,  QUIST, Arjan ,  PAVLOVIC, Elisabeth ,  ÖHMAN, Ove

Inventor： OSCARSSON, Sven ,  QUIST, Arjan ,  PAVLOVIC, Elisabeth ,  ÖHMAN, Ove

IPC: G01N33/543

CPC classification number: B82B3/00 ,  G01N33/54353 ,  G01Q80/00

Abstract: Objects, such as molecules, macormolecules, nanoparticles, cells and organelles are immobilised to a surface by covalent bonds and in a site-specific manner using an external source of energy, acting on the surface in the presence of said objects, when said surface and said objects have been chemically derivatised to present groups capable of forming reactive moieties when subjected to said source of energy. The exact location of the immobilisation is determined either by exposing the surface to said source of energy in a highly localised manner, or by creating site-specific defects or a pattern, to which groups capable of forming reactive moieties when subjected to said source of energy are first arranged. Said pattern may be in the form of electrodes, arranged on the surface.

Abstract translation: 如分子，大分子，纳米颗粒，细胞和细胞器的物体通过共价键和位点特异性方式通过使用外部能量源固定在表面上，在所述物体存在时作用在表面上，当所述表面和 所述物体已被化学衍生化以呈现当经受所述能量源时能够形成活性部分的基团。 固定的确切位置是通过以高度局部化的方式将表面暴露于所述能量源或通过产生位点特异性缺陷或图案来确定，当经受所述能量源时能够形成反应性部分的基团 首先安排 所述图案可以是布置在表面上的电极的形式。