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公开(公告)号:WO2023031910A1
公开(公告)日:2023-03-09
申请号:PCT/IL2022/050914
申请日:2022-08-22
Applicant: RAMBAM MEDTECH LTD.
Inventor: HADAD, Salim , LEFEL, Zvi
Abstract: A sterile closed system (20, 120) is provided that includes an airtight enclosure (40), an infusion-bag receptacle (44), medication-preparation tubing (48), one or more medication-preparation-tubing valves (50, 250), and an infusion-bag seal (46), which is configured to make an airtight seal with respective external surfaces of a medication port (36) and an IV tubing port (34) of an infusion bag (32). A medication- vial port (53) is configured to be sealingly coupled to a medication vial (30). The sterile closed system (20, 120) is configured such that a medication-port-interface needle (60), disposed within an enclosure interior (42) of the airtight enclosure (40), is sealingly couplable to the medication port (36) of the infusion bag (32), and an IV-tubing -port-interface spike (64), disposed within the enclosure interior (42), is sealingly couplable to the IV tubing port (34) of the infusion bag (32) without breaking the airtight seal between the infusion-bag seal (46) and the respective external surfaces of the medication port (36) and the IV tubing port (34) of the infusion bag (32). Other embodiments are also described.
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公开(公告)号:WO2022254423A1
公开(公告)日:2022-12-08
申请号:PCT/IL2022/050550
申请日:2022-05-25
Applicant: RAMBAM MEDTECH LTD.
Inventor: RON, Yonina , SANDOVSKY, Roei
Abstract: A needle assembly (20, 120, 220, 320) is provided that includes a needle (22) and a suture (24) coupled to the needle (22), and a needle guide tool (30, 130, 230, 330). The needle guide tool (30, 130, 230, 330) is configured to pass the needle (22) and the suture (24) through tissue of a body portion of a subject, and includes a needle guide (34, 134, 334), which is shaped so as to define a needle-guide surface (36, 136) that is configured to slidably contact a body-portion surface of the body portion without penetrating the body¬ portion surface. The needle guide tool (30, 130, 230, 330) also includes a proximal needle holder (40), which releasably holds the needle (22) such that a longitudinal segment (42, 142) of the needle (22) runs alongside the needle-guide surface (36, 136), such that sliding of the needle-guide surface (36, 136) distally along the body-portion surface advances the needle (22) within the body portion beneath the body -portion surface at a maximum depth set by the needle guide tool (30, 130, 230, 330). Other embodiments are also described.
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公开(公告)号:WO2022079710A1
公开(公告)日:2022-04-21
申请号:PCT/IL2021/051201
申请日:2021-10-07
Applicant: RAMBAM MEDTECH LTD.
Inventor: NAFTALI, Modi , SHAPIRA, Yinon
IPC: A61F2/16 , A61B17/122 , A61F9/007 , A61F9/00 , A61B17/04
Abstract: An ocular clip implant (22) used for securing an intraocular lens (IOL) (62) in an eye of a patient is provided which includes an IOL-engaging portion (26) disposed at a first end of the ocular clip implant (22). The IOL-engaging portion (26) is configured to grasp a portion of the IOL (62). An ocular-wall-engaging portion (28) is integrated with and disposed at a second end of the ocular clip implant (22). The ocular-wall-engaging portion (28) includes an anchor (29) transitionable from a first, straightened configuration to a second, non- straightened configuration to anchor the ocular clip implant (22) to a wall of the eye in order to secure the IOL (62) to the eye. Other embodiments are also described.
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公开(公告)号:WO2022013857A1
公开(公告)日:2022-01-20
申请号:PCT/IL2021/050844
申请日:2021-07-11
Applicant: RAMBAM MEDTECH LTD.
Inventor: FELD, Yair , KERNER, Arthur , TREYSTMAN, Alexander , ALMUZNINO, Gdaliahu , TSEFADIA, Issac
Abstract: A valve-splitting device (20, 120) for splitting a native or prosthetic valve cusp (4) is provided. The valve-splitting device (20, 120) includes a cover sheath (22) and a splitter (26, 126), which is removably disposed inside the cover sheath (22). The splitter (26, 126) includes a first over-the-wire cutter (30), which is shaped so as to define a guidewire lumen (40) that is configured to accept and slide over a guidewire (3); and a second opposing cutter (32, 132). The splitter (26, 126) is configured, upon distal advancement of the splitter (26, 126) out of a distal end of the cover sheath (22), to be opened such that the first over-the- wire cutter (30) and the second opposing cutter (32, 132) are separated from each other and are disposable on opposite sides of the cusp (4), such that closing the splitter (26, 126) by bringing the first over-the-wire cutter (30) and the second opposing cutter (32, 132) together cuts the cusp (4). Other embodiments are also described.
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公开(公告)号:WO2021152580A1
公开(公告)日:2021-08-05
申请号:PCT/IL2021/050085
申请日:2021-01-26
Applicant: RAMBAM MEDTECH LTD.
Inventor: KRITZMAN KADRON, Amnon , GRUENWALD, Ilan , YARMUT, Yehuda , HOLTZ, Arie Oscar , SINAI, Nir
Abstract: A user-controllable urinary catheter prosthesis (20) is provided for minimally - invasive insertion into a subject. The prosthesis (20) includes a proximal intra-urethral assembly (22), configured to be inserted entirely within a urethra (102) via a meatus (104). A user-activatable hydraulic activator (50) is disposed along a flexible intra-urethral catheter (30, 430), which is shaped so as to define a urinary outlet (40, 440) at a proximal end (41, 441) thereof. A distal bladder assembly (32, 132, 232, 332) is configured to be disposed in a bladder of the subject, and includes a bladder anchor (48). A hydraulic valve (60, 160, 260, 360) is configured to assume an open state, in which urine flow is allowed between the distal bladder assembly (32, 132, 232, 332) and the urinary outlet (40, 440); and a closed resting state, in which urine is entirely blocked from entering the distal bladder assembly (32, 132, 232, 332) and exiting the urinary outlet (40, 440). Application of pressure to the hydraulic activator (50) transitions the hydraulic valve (60, 160, 260, 360) from the closed resting state to the open state. Other embodiments are also described.
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公开(公告)号:WO2020188559A1
公开(公告)日:2020-09-24
申请号:PCT/IL2020/050312
申请日:2020-03-16
Applicant: RAMBAM MEDTECH LTD. , ZUR, Boaz , BACHAR, Yehuda
Inventor: ZUR, Boaz , BACHAR, Yehuda , ZUR, Gil
Abstract: A system and/or method are disclosed to inhibit sorption to a surface in a biological medium and/or biofouling by means of an alternating electric field. For example, one or more insulated electrodes may be positioned near the surface. For example, insulation may limit electric current flow between the biological medium and the electrode and/or between the surface and the electrode and/or between the electrodes. In some embodiments, the alternating charge in the vicinity of the surface may inhibit the buildup of biological films and/or sorption to the surface. For example, the system may be used to inhibit fouling of an implanted medical device (e.g. a catheter).
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公开(公告)号:WO2022113090A1
公开(公告)日:2022-06-02
申请号:PCT/IL2021/051424
申请日:2021-11-30
Inventor: GEPSTEIN, Lior , GRUBER, Amit , EDRI, Oded
Abstract: The present invention relates to products and methods for modulating cardiac function.
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公开(公告)号:WO2022101899A1
公开(公告)日:2022-05-19
申请号:PCT/IL2021/051323
申请日:2021-11-09
Applicant: RAMBAM MEDTECH LTD.
Inventor: RON, Yonina
Abstract: An extraocular muscle clip (22) for correcting strabismus includes upper and lower plates (24, 26) which are couplable together to sandwich and grasp extraocular muscle (42). A delivery tool (50) delivers the clip (22) and includes a shaft (52) and a muscle hook (56) that is slidable underneath the extraocular muscle (42) to position the lower plate (26) of the clip (22) underneath the muscle (42). An integrated blade (60) of the tool (50) cuts the extraocular muscle (42) subsequently to grasping of the muscle (42) by the upper and lower plates (24, 26) of the clip (22). One or more sutures (30) are coupled to the upper plate (24) and/or the lower plate (26) of the clip (22) and facilitate recoupling of the extraocular muscle (42) to a globe of the eye (40) following cutting of the extraocular muscle (42). Other embodiments are also described.
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公开(公告)号:WO2020240554A1
公开(公告)日:2020-12-03
申请号:PCT/IL2020/050582
申请日:2020-05-27
Applicant: RAMBAM MEDTECH LTD.
Inventor: HADAD, Salim , LEFEL, Zvi
IPC: A61J3/00 , A61J15/00 , A61J7/00 , A61J1/20 , A61M3/00 , A61M5/178 , A61M5/19 , A61M31/00 , A61M37/00
Abstract: A closed-system grinding syringe (10, 110) is provided for liquefying and delivering a solid dosage form (20), including a barrel (22), a fluid port (30) disposed on a bottom wall (28) of the barrel (22), and a plunger (32). A head (36) of the plunger (32) is insertable into and moveable within the barrel (22) such that (a) a portion of the barrel (22) defines a closed-system syringe chamber (46) between the bottom barrel wall (28) and a lower surface (64) of the plunger head (36), and (b) a plunger-head annular seal (42) forms a fluid-tight seal between an outer surface (44) of the plunger head (36) and a cylindrical inner surface (26) of the barrel (22). A solid-dosage-form support disc (60, 360) is disposed below a bottom plunger wall (38) so as to define a grinding compartment (62) between the lower surface (64) of the bottom plunger wall (38) and an upper surface (66) of the solid-dosage-form support disc (60, 360), and is shaped so as to define a plurality of holes (68, 368) through the solid-dosage-form support disc (60, 360).
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